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Biomedical subjects

P Brunner

Publications and source records attributed to P Brunner.

At least 73 records · Page 4Linked to original sources
PubMed1980

[Topography of posttraumatic fat embolism. Histological and statistical investigation of Gough-sections of the lung (author's transl)].

In 50 fat-stained and foil-mounted Gough-sections of entire lungs in accidental death cases the topographic areas of fat-embolic blood vessel occlusions were estimated. For control, the same investigations were made in cases of nontraumatic death. Accumulation of fat-embolism was found in the arterior thirds of the upper and middle areas of the lung, while in the basal, the central, and the posterior parts the incidence of fat-embolic occlusions is significantly rarer. Similar results, although to a lesser degree, were found in the lungs of non-traumatized patients. A statistical study evaluated whether right or left lobe, sex, age, or time of survival after trauma influence the incidence and intensity of fat-embolic occlusions in the lung. The results were discussed.

Accidents↗
PubMed1978

[Pericarditis of the heart niches (author's transl)].

Pericarditis of the Niches of the Heart (PNH) is an inflammatory process, progressing in stages, at the base of the pericardium. It is acquired during life and results finally in the formation of callosities. Lymphozytes, plasma cells, blood capillaries, and histiozytes as collagen fibres of various density characterize the PNH histologically. In 104 (48%) of 216 examined pericardiums of all age groups, PNH could be shown. The frequency of occurrence increases with age. No correlation to any fundamental disease was found. Mechanical influences are the primary cause of the origin of PNH. The pulsations affecting the plica of the base of the pericard as well as frictional, tensional and shear forces may initiate the process via small lesions of the serosa.

Acute Disease↗
PubMed1977

[Mechanisms of bronchial self-cleaning. Surface studies on the bronchial mucosa, bronchial basement membrane and subepithelial connective tissue. A scanning electronmicroscopic study].

Bronchial mucosa and bronchial basement membranes of man and of healthy slaughter animals were examined with the scanning electron microscope. The surface relief of the normal human bronchus mucosa is composed of a system of bulge-like prominences and valleys. There are parallel recesses and narrow valleys which run parallel to the longitudinal axis of the bronchus. Man and pig have the same kind of surface relief in bronchus. A fundamental different type of surface area relief is exhibited by the cow and the sheep. The bronchial basement membrane is a homogeneous plate with dune-like prominences and trough-shaped depressions. Often one can see perforations of variable size. The structures of the basement membranes have a great variability and no species-specifity. There are the same types of dysplasias in the bronchus mucosa in man and in animals. The differences are based upon in the wideness of the expansion and in the grade of the dysplasias in man.

Animals↗
PubMed1977

[Pulmonal silicone-embolism. Light microscopic, electron microscopic and enzymehistochemical investigations in the rabbit lung (author's transl)].

Artificial silicone-embolism in rabbits was produced by injection of Baysilon-antifoam into the ear vein. Electron microscopic and histochemical observations of the lung were made, concerning the toxicity and elimination of the embolic material. At 13 months after injection the embolic silicone was not significantly reduced in amount. The rabbit lung is unable to eliminate chemically inert silicone by enzymatic degestion. We noted serious defects of endothelial cells and pneumocytes, destruction of capillaries and local atelectases. These defects are preponderantly mechanical in origin, but may be caused by lack of substrate or energy in cells deprived of their blood supply. Atelectases are interpreted as a result of break-down in surfactant-synthesis.

Animals↗