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Biomedical subjects

N Soehendra

Publications and source records attributed to N Soehendra.

At least 181 records · Page 10Linked to original sources
PubMed1981

[Surgery in pregnancy from an endoscopy viewpoint].

Gastrointestinal endoscopy with flexible instruments is also a suitable method for pregnant women. Pregnancy is generally not a contraindication for use of the endoscopy, and additional special preparations are usually not necessary. In cases with unclear upper abdominal pain the esophagogastro-duodenoscopy with thin instruments is more suitable than X-ray examination. An indication for the coloscopy can occur in patients with relapsing peranal hemorrhage or diarrhea. For obstructive jaundice ERCP with PTC is the diagnostic method of choice.

Cholangiopancreatography, Endoscopic Retrograde↗
PubMed1981

Early post-operative endoscopy after biliary tract surgery.

Immediate post-operative complications such as obstructive jaundice, biliary fistulae or gastrointestinal hemorrhage, occurring after biliary tract surgery can be diagnosed endoscopically. The causes of bile flow obstruction and leakage from the common bile duct can be identified using ERC. In many cases the diagnosis can be followed by endoscopic treatment, therefore obviating re-laparotomy. Between 1972 and 1979 we carried out early post-operative ERC or esophago-gastro-duodenoscopy in a total of 94 patients after biliary tract surgery. In 75 patients with residual gallstones and 4 cases with overlooked stenoses of the papilla, successful papillotomies were carried out. The procedure was unsuccessful in one case with an extremely narrow papilla. Complete removal of stones was achieved in 72 cases. In two other patients with gastroduodenal stress ulcers, bleeding was stopped by submucosal infiltration.

Bile Duct Diseases↗
PubMed1981

Pancreatic oncofetal antigen in pancreatic juices. Partial chemical characterization and diagnostic application of a pancreatic cancer-associated antigen.

Antisera were raised in rabbits to an antigenic structure present in fetal pancreas tissue, pancreatic tumor tissue, and pancreatic juices and in sera obtained from pancreatic cancer patients. The first chemical data indicate that this pancreatic oncofetal antigen is distinct from CEA, NCA, and NCA2 and is not glycolipid in nature. Immunoelectrophoretic analyses demonstrate that pancreatic oncofetal antigen is a protein or a glycoprotein, which displays microheterogeneity. The apparent molecular weight of the basic unit of pancreatic oncofetal antigen is estimated to about 40 K. So far 234 pancreatic juices have been investigated for pancreatic oncofetal antigen. Pancreatic oncofetal antigen was detected within the pancreatic juices from 59 of 74 (80%) pancreatic carcinoma patients but could be traced in only 16%-26% of samples obtained from patients with other diseases.

Adult↗
PubMed1981

[Viscero-cutaneous hemangiomatosis].

A 3 1/2-year-old girl with multiple hemangiomas of the skin developed a severe anemia soon after birth due to intestinal hemorrhage. She required multiple blood transfusions for the next 3 years. At the time of operation 32 hemangiomas in the duodenum, small and large bowel were resected. The postoperative course was uneventful, the child had no further blood less. An extensive hemangioma in the lower esophagus was left in place.

Child↗
PubMed1980

[Endoscopic control of gastrointestinal bleeding by sclerosing injections. Application to peptic ulcers and polypectomies (author's transl)].

Three endoscopic methods are available to control gastrointestinal bleeding. Electrocoagulation suffers from two defects: the depth of cauterization is difficult to assess, and removal of the catheter, which sometimes adheres to the tissues, may cause re-bleeding. Laser coagulation is relatively more effective but costly. Sclerosing injections using 1% polidocanol are easier and cheaper. The authors have applied the latter method to 63 cases of gastrointestinal haemorrhage, including 37 peptic ulcers, 4 angiodysplasias of the stomach, 2 cases of Mallory-Weiss syndrome, 1 bleeding erosion and 19 haemorrhages consecutive to the excision of gastric or colonic polyps. Bleeding was stopped in 61 cases and remained under control in 52; it recurred in 9 patients. Two patients required emergency surgery.

Endoscopy↗
PubMed1980

[Fiberscopic obliteration of esophageal varices (author's transl)].

We are reporting our 2 years experience in the fiberscopic sclerotherapy of esophageal varices. 170 patients from 15-83 years of age were treated (61 females and 109 males), the majority being around 50 years of age. In 162 cases, the cause of the portal hypertension was cirrhosis of the liver and in 8 cases thrombosis of the splenic or portal vein. 47 patients were treated during acute bleeding, 101 in the interval, and 22 prophylactically. Using the modified intravascular technique, most varices could be sclerosed after a maximum of three treatments. In 83%, acute hemorrhages were stopped. The hospital mortality amounted to 30%, while in the interval group only it was 5%. None of the prophylactically treated patients died during their stay in hospital. The mortality after an average of 11.2 months amounted to 11.8%: The main cause was liver failure. Bleeding reoccurred in 11.2% and resulted in death in every fifth case. The most common complication, namely stenosis, arose in 16 cases and 4 of these necessitated dilation therapy. Esophagothoracic fistulae occurred in 2 cases and could be cured by siphon drainage. The rate of complication amounted to 10.6%, without any lethal outcome.

Adolescent↗
PubMed1980

Palliative bile duct drainage - a new endoscopic method of introducing a transpapillary drain.

An endoscopic method for placing an internal drain in the bile-duct is described. Compared to the nasobiliary suction-tube this method has the advantage that it guarantees the physiological flow of the bile into the duodenum, and that the patient is in no way inconvenienced. For high-risk or inoperable cases the method can be considered as an alternative to choledochoduodenostomy.

Ampulla of Vater↗
PubMed1980

Diagnosis of pancreatic carcinoma by means of endoscopic retrograde pancreatography and pancreatic cytology.

Endoscopic retrograde pancreatography (ERP) combined with pancreatic juice cytology, was performed in 14 patients with pancreatic carcinoma confirmed at subsequent laparotomy. ERP demonstrated duct abnormalities that were diagnosed as carcinoma in 86% of the cases and as suggestive of carcinoma in another 14%. Cytology was positive in 86% and suspicious in 7%. By combining both methods, all 14 carcinomas were correctly identified. Thus, in our hands, ERP and pancreatic juice cytology proved to be the most sensitive and reliable methods in detecting pancreatic carcinoma. On the basis of these promising results it is proposed that pancreatic juice cytology, which is a no-risk method, should be employed in all elderly patients with unexplained abdominal complaints, to screen them for early pancreatic carcinoma.

Carcinoma↗
PubMed1979

[Bile-duct-stenosis after operation of the common bile-duct with T-tubes (author's transl)].

3 stenosis of the bile duct were observed in a postoperative study out of 25 patients, who underwent operations of the bile-duct-system and had T-tubes. These patients had no complaints. One patient had a reanastomosis of the bile duct, the stenosis was in the area of the anastomosis. The T-tubes of 2 patients were postoperatively under traction, which might have favoured the stenosis. The possibilities of intravenous cholangiography and endoscopic-retrograde cholangiography are discussed.

Biliary Tract↗
PubMed1979

[G. I. diagnostics; its ranking and interdisciplinary organisation (author's transl)].

The complicated and expensive diagnostic apparatus available today has to be applied in an orderly sequence. This order depends on certain prerequisites, e.g. on the disease, urgent complications, patient tolerance, apparatus potential, hospital structure and organisation etc. The more rational the indication is to use certain methods, the more efficient will be the results. The appropriate concepts and suggestions for certain general and specific examples, used by us at present are demonstrated. Complicated and expensive diagnostic procedures have to be decided primarily on an interdisciplinary level. The increased costs of these procedure are balanced by a decrease in hospital stay and fewer operative explorations too. At other places different actions will be taken for equally good reasons.

Gastrointestinal Diseases↗
PubMed1978

[Modern endoscopy in surgery].

Our own endoscopic experience in surgical gastroenterology is based on 5000 esophago-gastro-duodenoscopies, 650 coloscopies and 1200 endoscopic retrograde cholangio-pancreaticographies. Endoscopic diagnosis and therapy is pre-, intra-, and postoperatively well established today. Improvements of preoperative diagnosis in certain surgical diseases let hope for further successes in this field. Endoscopic procedures and operations reduce the patient's risks to a minimum. Well established endoscopic technique may substitute and support certain surgical procedures.

Endoscopy↗
PubMed1978

Surgical emergency cases--endoscopic treatment.

For gastrointestinal surgery endoscopy gains more and more importance. Besides the desired improvement of pre-, intra- and postoperative diagnosis multiple therapeutic procedures proved to be practicable. Of special interest are those methods, which can be used successfully in emergency cases. Here the foreign body dislodgement, the stopping of hemorrhage and the introduction of tubes in cases of ileus or dehiscence of the suture have to be mentioned. The endoscopic treatment is very often a complementary or palliative one and not so much an alternative. These methods are applied to patients at high risk.

Adolescent↗