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Biomedical subjects

N Soehendra

Publications and source records attributed to N Soehendra.

At least 163 records · Page 9Linked to original sources
PubMed1985

[Endoscopic injection treatment].

Nowadays injection treatment is not only used for sclerosing esophageal varices but also for stopping hemorrhage from mucosal lesions. This method is equally effective for treatment of hemorrhages after polypectomies and papillotomies. New indications for this method are benign and malignant stenoses of the esophagus. Good results in sclerosing of varices and of stopping hemorrhage have been confirmed very often; however further experience is needed in the treatment of stenoses.

Ampulla of Vater↗
PubMed1984

[Stress tolerance of patients with hemorrhage from ulcus ventriculi sive duodeni].

448 patients with severe haemorrhage from gastroduodenal ulcera during the last 15 years are presented. Within this period indication, organisation and the choice of method have changed in 3 phases. Included are the endoscopic diagnosis and treatment with very good results. As a result of endoscopy there is a negative selection of patients for surgery causing a depression of the results after surgical treatment. The propagation for early indication even in high risk patients still has validity.

Duodenal Ulcer↗
PubMed1983

[Infiltrating injection in the management of post-papillotomy hemorrhages].

Treatment was required in nine cases (1.7%) of haemorrhage after endoscopic sphincterotomy performed in 508 patients during 1981/82. Infiltrations with adrenalin (1: 10 000) and 1% polidocanol solution resulted in immediate arrest of haemorrhages in all cases. The endoscopic intervention could thus be completed successfully without further delay. The haemostatic effect was, without exception, permanent. There were no specific complications or late reactions.

Cholangitis↗
PubMed1983

[Cholesterol content of bile-duct stones].

The cholesterol content of bile-duct stones from 40 patients after cholecystectomy was compared with 22 gall-bladder stones. There were 18 (82%) cholesterol-rich stones (cholesterol content more than 60% of dry weight) among gall-bladder stones, but only 12 (30%) among bile-duct stones. Eight bile-duct stones (20%) contained fibrous material, a further seven (18%) had a cholesterol-rich nucleus and cholesterol-poor outer layer. These findings indicate that residual fibres or small migrated gall-bladder stones can form the nidus for the growth of choledochal stones. The cholesterol content of bile-duct stones did not correlate with the age of the patient, time since cholecystectomy or cholesterol saturation of hepatic bile.

Aged↗
PubMed1983

Morphological alterations of the esophagus after endoscopic sclerotherapy of varices.

With the combined peri- and intravascular sclerosing technique esophageal varices can be completely eliminated in an average of three treatment sessions. In order to check the success of the procedure, endoscopic and histological findings at the various stages of treatment after sclerosing with 1% Polidocanol were compared. Clinical and autopsy findings are in agreement. After sclerosing, necroses of the mucosa and intramural inflammations occur regularly in the first week. The varices are thrombosed. Later, the inner wall of the esophagus is cicatricially changed. Histologically the fibroses extend transmurally and in some parts even reach the musculature.

Adolescent↗
PubMed1983

Bile acid pattern and cholesterol saturation of bile after cholecystectomy and endoscopic sphincterotomy.

The effect of endoscopic sphincterotomy on bile acid composition and cholesterol saturation of bile has been studied in cholecystectomized patients. Individual bile acids and biliary lipids were measured in hepatic bile of 13 cholecystectomized females aged 56.8 +/- 16.6 years more than 9 months (mean 16.7 +/- 8.8 months) after sphincterotomy and of 12 cholecystectomized females aged 59.3 +/- 11.5 years who served as controls. The sphincterotomy group exhibited a significantly (p less than 0.01) higher percentage of chenodeoxycholic acid in bile--39.2 +/- (SD) 7.7%--than the controls with cholecystectomy only (29.1 +/- 7.4%), but showed no differences in the proportion of cholic acid (32.4 +/- 6.2 vs. 33.6 +/- 7.8%). The percentages of the secondary bile acids, deoxycholic acid (25.0 +/- 8.8 vs. 32.3 +/- 8.3%), and lithocholic acid (1.7 +/- 0.8 vs. 2.6 +/- 2.3%) were lower, but these differences were not statistically significant. The biliary lipid composition in the sphincterotomy group was not different from that in the controls, resulting in a similar cholesterol saturation index in both groups (1.87 +/- 0.60 vs. 2.02 +/- 0.60 according to Carey and Small; 1.45 +/- 0.32 vs. 1.55 +/- 0.32 according to Hegardt and Dam). These findings do not demonstrate any alterations of the bile composition after sphincterotomy which may be expected to have undesirable effects on the biliary and/or gastrointestinal system.

Adult↗
PubMed1983

[Methods of injection in hemostasis of the gastrointestinal tract].

Endoscopic sclerotherapy to stop acute gastrointestinal haemorrhage is simple as well as inexpensive in comparison to laser or electrocoagulation. In this paper a report on our experiences during the last five years is given. 187 patients with different bleeding sites in the upper and lower digestive tract have been treated. In 85.6% a definite haemostasis could be achieved. In 9.1% the result was of short duration. The method did not succeed in 5.3%. No complication was observed.

Acute Disease↗
PubMed1983

[Cause of pulmonary disorder following sclerosing therapy].

In order to elucidate pulmonary changes after sclerotherapy of esophageal varices animal experiments were performed. Polidocanol was injected into the submucosa of the distal esophagus and into a branch of the pulmonary artery. The submucous infiltration of the lower esophagus often causes congestive pulmonary alterations near the injection area. The subsequent disturbances of gas exchange as well as the negative inotropic effect of Polidocanol demands therapy in a number of cases.

Animals↗
PubMed1983

[Experiences with fiber endoscopy sclerosing of esophageal varices with polidocanol].

Endoscopic sclerosing of oesophageal varices is only a palliative measure, which should be performed when the bleeding came to a standstill. The aim of treatment is to sclerose all visible varices in the oesophagus. This can be done with intervals in 4 to 5 weeks. Anaesthesia is not necessary. We observed perforations in 1%, stenosis of the oesophagus in 10% (n = 414 cases), treated in the last 4 years. The results obtained until now confirm our impression that, at present, injection sclerotherapy is the method of choice.

Adolescent↗
PubMed1982

[Endoscopic injection for haemostasis in the gastrointestinal tract].

Haemostasis by endoscopic injection was attempted in 169 patients with acute gastrointestinal haemorrhage between 1976 and 1982. Despite various caused initial haemostasis in the upper and lower digestive tract was achieved in 95%. Recurrences were seen in 10%. Definitive haemostasis thus was 85%. Best results were obtained in Mallory-Weiss syndrome, angiodysplasia and post-polypectomy haemorrhage. The success rate for gastroduodenal ulcers was around 75 to 80%. Until now no complications have been observed. Apart from effectiveness, the injection method has the advantage of simplicity and little technical needs over other procedures.

Endoscopy↗