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Biomedical subjects

N Okazaki

Publications and source records attributed to N Okazaki.

At least 181 records · Page 10Linked to original sources

Acoustic analysis of the inflation sound in Eustachian catheterization.

To check the reliability of the Eustachian tube catheterization as a test of tubal dysfunction, a soundspectrographic analysis of inflation sound was carried out in 130 tubes. A close correlation between each tubal condition classified by objective tests and their soundspectrographic features indicated the reliability of the test. The origin of an inflation sound in obstructive tubes which displayed three sonagraphic types was examined by a tubal model. It was revealed that the stenotic sound mainly originated from turbulent air at the tubal orifice.

Catheterization↗

Significance of levator muscle sling formation in cleft palate surgery: evaluation by electrical stimulation.

The effect of levator muscle sling formation in cleft palate surgery was evaluated by electrical stimulation of the muscle at surgery. Palatal movement before and after sling formation was recorded through a force transducer. After muscle sling formation, the soft palate was elevated more effectively toward the retropharynx and its mobility increased remarkably. The surgical procedure, which had been proposed on the basis of anatomic considerations, was proved to be effective for improving velopharyngeal function.

Cleft Palate↗

Role of the tensor veli palatini muscle in movement of the soft palate.

To examine the role of the tensor veli palatini muscle in palatal movement, we conducted 1) quantitative measurement of palatal movement by selective stimulation of the tensor and levator muscles, and 2) EMG recording of the two muscles during phonation. The results were: 1) negligible palatal movement upon tensor stimulation, despite a marked velar elevation by levator stimulation; and 2) little EMG activity of the tensor and marked EMG activity of the levator during phonation. It was concluded that the tensor plays no role in the palatal function.

Animals↗

Hepatocellular carcinoma associated with erythrocytosis. A nine year survival after successful chemotherapy and left lateral hepatectomy.

A case of hepatocellular carcinoma associated with erythrocytosis is described. The patient was successfully treated with a combination chemotherapy of 5-fluorouracil, mitomycin C, cyclophosphamide and chromomycin A3, which was followed by a left lateral hepatectomy, and has survived for more than 9 years after the operation without any signs of recurrence. With the regression of hepatic tumor by the anticancer chemotherapy, the remission of erythrocytosis was observed, indicating that the tumor was producing erythropoietin. The data suggest also that erythrocytosis could be a marker for evaluation of chemotherapeutic effects in some patients with hepatocellular carcinoma.

Carcinoma, Hepatocellular↗