Search PubMed⌕ Search

Biomedical subjects

N Ogino

Publications and source records attributed to N Ogino.

At least 73 records · Page 4Linked to original sources
PubMed1988

Involvement of fibronectin in in vitro regeneration of retinal pigment epithelium.

Argon laser photocoagulation was placed on the confluent monolayer of cultured chick retinal pigment epithelial cells as a model of the regeneration process of retinal pigment epithelium after laser burn. The intense fibrillar net immunofluorescent pattern of fibronectin appeared on the burnt area from 2 h after the laser application, before the beginning of tissue reconstruction. Fibronectin was observed for several days, then became undetectable before the complete regeneration of retinal pigment epithelial cells. This indicates that fibronectin is involved in the early regeneration process of retinal pigment epithelium.

Animals↗
PubMed1987

Subretinal strands. Tissue culture and histological study.

Subretinal strands in proliferative vitreoretinopathy removed during vitreous surgery in ten cases were studied histologically; tissue culture was taken from five of the ten cases to obtain more material for investigation. Tissue culture was successful in all five cases. The cultured tissue just next to the original strand preserved the characteristics of the original tissue, whereas the portion distal from the original strand did not. Definite and/or suspected retinal pigment epithelial cells (RPE) were found in seven of ten original strands and four of five samples of cultured material. RPE were considered to be a predominant component of subretinal strands.

Culture Techniques↗
PubMed1987

Retinal pigment epithelial cells produce fibronectin.

Antichick fibronectin antiserum, noncross-reactive to bovine fibronectin, was prepared to determine the production of fibronectin by cultured chick retinal pigment epithelial cells which were grown in the presence of fetal bovine serum. The typical fibrillary net pattern of fibronectin was observed by an indirect immunofluorescent technique when this specific antiserum reacted with cultured chick retinal pigment epithelial cells. Cultured chick retinal pigment epithelial cells were shown to produce fibronectin.

Animals↗
PubMed1987

Cell components in proliferative vitreoretinopathy: immunofluorescent double staining of cultured cells from proliferative tissues.

Intermediate filament proteins in cultured cells from epiretinal membranes of 5 cases of proliferative vitreoretinopathy and subretinal strands of 2 cases were immunohistologically characterized. Double staining technique after colcemid treatment revealed that either keratin-positive or vimentin-positive cells were found with different ratios depending on the cases. Both positive and both negative cells were also observed. Desmin and glial fibrillary acidic protein were totally negative.

Adult↗
PubMed1987

Idiopathic epiretinal membranes with spontaneous posterior vitreous separation.

A posterior fundus examination around the macula was performed for the patients diagnosed spontaneous posterior vitreous separation. Of 898 eyes, 358 eyes had epiretinal membranes. The presence of membranes did not correlate to sex. The 2-fold greater incidence was observed in the aged group and emmetropic patients. For the progression, age, sex or refractive error alone was not significant, while aged, emmetropic patients showed greater incidence. The longer duration of the membrane existence also indicated the greater progression.

Age Factors↗
PubMed1987

Juvenile retinal detachment.

The features and prognoses of 802 cases (908 eyes) of retinal detachment from 8 months to 19 years of age were studied with the patients divided into three age groups: 65 eyes in group I (0-9), 259 eyes in group II (10-14), and 584 eyes in group III (15-19). Eyes in group I were different from the others in many respects. In group I, traumatic detachments, preoperative complications, four-quadrant detachments, and eyes with undetected breaks were more frequent, and the prognosis was worse than in the other groups. Holes with lattice degenerations were most frequent in group III eyes having no history of trauma. Group III resembled adult retinal detachment and group II was thought to be the transitional type.

Adolescent↗
PubMed1986

Omental transposition and skin graft in patients for advanced or recurrent breast cancer.

Nine patients, including 4 with primary advanced breast cancer (stage IV) and 5 with local recurrent cancer, underwent chest wall reconstruction using an omental flap and mesh skin grafting. In 2 of these patients the defect of bony chest wall was reconstructed with an acryl-resin plate and omental flap. The postoperative course in all patients was uneventful, except for a slight necrosis on the transposed mesh skin. Flail chest or dyspnea did not occur in those with a bony chest wall reconstruction. The immediate postoperative performance status in 6 of 9 patients and also quality of life improved.

Adenocarcinoma↗
PubMed1986

Effects of phenothiazines on cultured retinal pigment epithelial cells.

Phenothiazines (chlorpromazine, trifluoperazine, prochlorperazine, and fluphenazine) showed dose-dependent inhibition of phagocytosis of latex particles by cultured chick retinal pigment epithelial cells at concentrations of 10(-5)-10(-14) mol/l. Calmodulin antagonists (W-5, W-7, W-12, and W-13) showed similar effects as phenothiazines at concentrations of 10(-5)-10(-14) mol/l. These reactions were partially reversible at a concentration of 10(-9) mol/l. Cells cultured for 3 days in the presence of 10(-5) mol/l chlorpromazine or 10(-5) mol/l W-7 demonstrated morphologic alterations in their microvilli which were similar to those seen after cytochalasin B treatment, i.e., thinning and elongation of the microvilli with honeycomb-like changes.

Animals↗