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Biomedical subjects

N Mygind

Publications and source records attributed to N Mygind.

At least 163 records · Page 9Linked to original sources

Scanning electron microscopy of the human nasal mucosa.

Nasal biopsies are taken from normals and from patients suffering from perennial rhinitis, nasal polyps, hay fever or atrophic rhinitis. The biopsies from the inferior nasal turbinate are studied in a scanning electron microscope. In conclusion, allergic reactions have only a slight, direct influence on the ultrastructure of the mucous membrane. Contrary to this, the surface of the nasal mucosa is characteristically altered in atrophic rhinitis. By chance it was observed how flagellated bacteria invades the mucous membrane by fastening to the epithelial cells, which consequently are expelled.

Bacteria↗

Local effect of intranasal beclomethasone dipropionate aerosol in hay fever.

The effect of a daily dose of 400 mug beclomethasone dipropionate aerosol intranasally has been investigated in a double-blind cross-over trial in 29 patients with hay fever. The effect on the nasal symptoms was so pronounced in 25 patients that further symptomatic treatment was unnecessary. Beclomethasone dipropionate aerosol had, on the other hand, no direct effect on itching in the eyes, which is in accordance with the fact that biochemical investigations did not show any sign of suppression of the adrenal function. It is concluded that beclomethasone dipropionate aerosol intranasally is an effective and apparently harmless way of controlling the nasal symptoms in hay fever.

17-Ketosteroids↗