[Thalamic bleeding--its C.T. findings and treatment (author's transl)].
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Biomedical subjects
Publications and source records attributed to M Shah.
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Classification of intracerebral hematoma (lateral type) with C.T. was tried. And also, the relationship among the location of the hematoma, the shift of the lenticulostriate arteries and the prognosis of hemiparesis was verified. The results were as follows; 1) The location of the hematoma was classified into four types: 1. anterior type (the hematoma mainly located in the anterior limb of internal capsula). 2. Posterior type (the hematoma mainly located in the posterior limb of internal capsula). 3. lateral type (the hematoma mainly located just below the insula). 4. spread to the all direction type. 2) The lenticulostriate arteries was divided into three portions: L1 portion is the part from the origin at the middle cerebral artery to the knee point, L3 is the part of the distal portion of the lenticulostriate arteries, and L2 portion in the part between L1 and L3 portions. L1 portion was mainly shifted medially in the anterior type of the hematoma. L2 portion was mainly shifted medially in the lateral type of the hematoma. L3 portion was mainly shifted in the posterior type of the hematoma. L1, L2, L3, all portions were shifted medially in the type in which the hematoma spread to all directions 3) The prognosis of the hemiparesis was best in the lateral type of the hematoma, and next in the anterior type. In the posterior type and all spread type, it was worst.
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Two hundred term healthy neonates were examined and 14 anthropometric measurements were taken in the face and ear region. Difference between the sexes was observed in ear length, ear breadth, and philtrum. Significant correlation was found between ear placement and ear length; and outer and inner canthal distances (p less than 0.001). The paper provides baselines data for facial growth measurements and discusses the utility of these measurements in detecting dysmorphogenesis in neonates.
Gastroesophageal reflux (GER) is a common condition affecting children. The clinical presentation varies widely from innocuous spitting up to life threatening apnea. Various diagnostic tests are available to document the etiology, presence or complications of GER. In most cases, conservative approach is sufficient. In complicated cases, pharmacotherapy is indicated while surgical therapy is reserved for resistant cases with complications.
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The causes of conjunctivitis and keratoconjunctivitis in 388 patients who attended eye casualty departments in Karachi, Pakistan, during a 5 month period were investigated. Most of these infections were diagnosed as adenovirus (291, 75%) or bacterial (71, 18.3%). Of the remainder, 9 cases (2.3%) were caused by herpes simplex virus and 7 (1.8%) by Chalmydia trachomatis. There was no evidence of typical active trachoma in this urban population. Bacteria or Candida albicans were also grown from 44 of the adenovirus cases (15%). Many of the bacteria grown from eyes in this study were resistant to antibiotics, probably because of inadequate and/or inappropriate self-medication with antibiotics in this community.
Behavioral and sociodemographic correlates of high fat/calorie food consumption were examined in a population-based sample of working adults (N = 2038 men; N = 2335 women). Relative weight, dieting history, and cigarette smoking were significantly related to total energy intake from high fat/calorie foods. Relative weight was positively related to the intake of meat, eggs, fried potatoes, and fats. Current dieting to lose weight was associated with a lower intake of all foods, except alcohol and fats. These foods were unrelated to dieting status in men and positively related to dieting status in women. Physical activity and smoking were related to higher intake of high fat/calorie foods. Smokers consumed fewer sweet foods than nonsmokers, however. These results underscore the importance of controlling for dieting status, as well as other behavioral and demographic variables, in population studies of dietary intake. They also suggest factors that may be important in the etiology of unhealthy eating patterns and potential targets for dietary intervention.
In this article, we initially review several problems associated with the design and interpretation of certain types of experiments currently used to study wound healing, drawing attention to the fact that applications for standard statistical techniques in the analysis of the experimental results are often of limited value. We then argue that, because of the special nature of wound healing data, curve fitting of empirical model equations can often provide a convenient way to summarize treatment effects with large data sets. The various ways in which this technique could be used to facilitate the interpretation of experimental wound healing results are then explored. To illustrate this approach, we then took several wound healing experiments and introduced possible models that could be used, paying particular attention to simple equations with the smallest possible number of parameters. For each equation, the way that the parameters of the model could be interpreted with regard to the biologic effects represented is given. Examples are given to show the application of each model discussed theoretically in the interpretation of some typical experimental data sets.
BACKGROUND: Since 1988, all blood donations in the United States have been screened for antibodies to human T-lymphotropic virus type I (HTLV-I). However, the sensitivity of current serologic tests for the detection of HTLV type II (HTLV-II) antibodies and the diagnostic utility of direct tests for HTLV-I and -II using polymerase chain reaction (PCR) are poorly defined. STUDY DESIGN AND METHODS: Five hundred sixty-nine HTLV-I- or -II-seropositive and 687 age- and sex-matched seronegative samples from a high-risk population at an inner-city emergency department were selected. All samples were tested with four HTLV enzyme immunoassays (EIAs), one Western blot assay and one type-specific Western blot assay, one HTLV type-specific EIA, and a research HTLV-I/II PCR kit. RESULTS: Sensitivity of the various EIAs ranged from 95.1 to 99.5 percent, and specificity ranged from 97.2 to 99.4 percent. PCR performed in duplicate without selective retesting had lower sensitivity (85.1 %) and specificity (88.0%). However, PCR detected 20 (3.2%) HTLV-I-positive and 47 (7.5%) HTLV-II-positive samples among the 627 samples that were negative in all EIAs. The type-specific EIA and PCR assay had the highest rate of concordance in classifying samples as either HTLV-I or II, with the type-specific EIA and type-specific Western blot having the next highest rates of concordance. CONCLUSION: In this sample set from a population at high risk for HTLV-II, screening with HTLV-I/II PCR had lower sensitivity and specificity than that with EIAs. However, 4.1 to 10.8 percent of samples were PCR positive but seronegative for HTLV-I or -II, and their true infection status remains undetermined.
Medical records of 134 patients with Staphylococcus aureus bacteremia at the Cincinnati General Hospital during 1975-1977 were reviewed. Bacteremia was community-acquired in 48 patients and hospital-acquired in 73 patients. In addition, 13 patients were on chronic hemodialysis. In 22 patients, bacteremia was associated with an infected intravenous catheter; all except one of these patients acquired the infection in the hospital. Thus 21 of 73 (29%) episodes of hospital-acquired S aureus bacteremia were associated with an infected intravenous catheter. Four of the 22 patients with intravenous catheter-associated bacteremia had endocarditis (18%). The overall incidence of endocarditis in this study was 16% (21 of 134 patients). This contrasted with the much higher incidence of endocarditis (64%) in Staphylococcal bacteremia reported from this same hospital in patients during 1940-1954. Possible reasons for this difference are discussed.