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Biomedical subjects

M Moser

Publications and source records attributed to M Moser.

At least 379 records · Page 21Linked to original sources
PubMed1981

[Maintenance of a steady level of vigilance during the electronystagmographic investigation (author's transl)].

During electronystagmography (ENG) a magnetic tape is used and with it simple arithmetical problems including the solutions are presented in time intervals of 15 seconds, the solutions being correct or incorrect in a random succession. The test person holds a simple electric bell in this hand having been instructed to press the bell-button once or twice, depending whether the announced solution is correct or not. During the recording of the ENG these signals are made visible as rectangular impulses on a separate trace, thus allowing control over the degree of cooperation of the test person. To prove the value of the described procedure 20 normal persons were investigated after sleep deprivation of one night with and without presentation of arithmetical problems, both investigations changing alternately. The evaluation of the parameters of ENG clearly demonstrates a significant difference in both experimental procedure, particularly in respect of frequency and angular velocity at the slow nystagmus phase. The described method has not only proved valuable for increasing vigilance but also not for maintaining a steady level of vigilance during the electronystagmographic investigation.

Arousal↗
PubMed1980

[Irritation of vestibular center and "ecriture centrale" (author's transl)].

To confirm the value of the écriture centrale during the pendular test clinical and animal experiments were performed. The écriture centrale was recorded in 12% of 710 subjects otoneurologically examined, mainly in groups with commotio or contusio cerebri, diseases of the brain and vertebrobasilar insufficiency. Also écriture centrale was a sign of functional disturbacne after lumbar occiptal puncture without organic lesion and in boxers. In six rabbits écriture centrale was observed after occipital puncture.

Animals↗
PubMed1980

[Central disequilibrium in boxers (author's transl)].

In 20 boxers the vestibular examination was made with pendular test. In 75% central vestibular changes of the per-rotatary nystagmus reaction were observes. Only in 3 cases the electronystagmogram was unremarkable. In 4 cases the EEG was normal although the nystagmus reaction was pathologic indicating central disorders.

Adult↗
PubMed1980

[Measurement of the colloid osmotic pressure from plasma density by means of the mechanical oscillator technique (author's transl)].

The colloid osmotic pressure of plasma is a clinically and physiologically important variable. Like the plasma density, it is a function of the total concentration of plasma proteins. Thus, plasma colloid osmotic pressure can be determined from measurement of the plasma density. Minor variations are caused by variations of the albumin-globulin ratio and, much less frequently, by increased concentration of low molecular substances in the plasma. The direct measurement of the colloid osmotic pressure is a time consuming and complex procedure. The determination of the plasma density using the mechanical oscillator technique is a simple and fast procedure. From our results we were able to derive and prove the applicability of an equation which permits the calculation of the colloid osmotic pressure from the measured values of the plasma density. The plasma volume needed for the measurement is 0.2 ml, the measuring time amounts to a few seconds.

Blood Proteins↗
PubMed1980

[Histamine reduction by means of oncolytically active and oncolytically non-active clostridial strains (author's transl)].

Spores and vegetative forms of oncolytically active and oncolytically non-active clostridial strains were tested for histamine reducing activity (isolated ileum of guinea pig used for testing, waterbath method acc. to Magnus, Fig. 1). Culture media and the washed intact material did not show any or only very little effectiveness. On the other hand the fractionated, charges diminished histamine standard solutions except for very little remaining activity in the case of all strains. This effect was stronger in vegetative forms than in spores (Fig. 2). The histamine effect on the isolated organ was generally increased by means of culture media as well as by the washed intact material. In this respect, preparations of non-lytic strains showed a slightly higher effectiveness than preparations of lytic clostridial strains (Fig. 2). It was shown in earlier investigations (cf. bibliography) that the charges of clostridial strains decompose plasmakinin (synthetic bradykinin) at varying rates. Reduction of histamine activity by means of clostridia could lead to a decrease of the microcirculation and capillary-permeability in the tumor tissue (as hypothesized for bradykinin) and thereby favour its disintegration.

Animals↗
PubMed1980

[The assessment results of patients with neurootological symptoms (author's transl)].

Neurootological symptoms in 710 patients were assessed by otorhinolaryngological examination, audiometry, vestibulometry, electroencephalography, echoencephalogram, ophthalmological and neurological examination, skull, temporal bone and cervical spine X-rays, electrocardiography, and lumbar puncture. Where abnormal findings occurred further assessments such as brain-scan, vertebral angiography, Xenon clearance and computerized axial tomography were done. Analysis of the case histories showed that there were 45 patients with organic lesions of the brain, 79 with cerebrovascular disease, 68 with postconcussional syndrome, 88 with cervical spine disease, 56 with the Menière syndrome, 36 with disturbed circulatory control, 141 with heretodegenerative hearing loss, acoustic trauma, Bell's palsy or psychosomatic vertigo, and 97 patients who could not be classified. These large numbers of serious problems confirms that it necessary to thoroughly investigate as described patients with neurootological symptoms.

Blood Circulation↗