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Biomedical subjects

M Lengyel

Publications and source records attributed to M Lengyel.

At least 91 records · Page 5Linked to original sources

Echocardiographic criteria for the diagnosis of congestive (dilated) cardiomyopathy.

M-mode echocardiograms of 29 patients with congestive cardiomyopathy verified by either complete angiographic study or autopsy were compared with those of normal persons in order to find indices which separate individual cases. Three indices to be used as echocardiographic criteria of congestive cardiomyopathy are proposed: E-point separation over 10 mm, left ventricular end-diastolic dimension over 55 mm, and per-cent fractional shortening below 20%. It is suggested that segmental wall motion disturbances cannot be considered as criteria for congestive cardiomyopathy. In 76 patients with clinically suspected congestive cardiomyopathy the diagnosis was supported by the combination of the above-mentioned criteria. The authors recommend the use of these criteria for screening of the disease in the population.

Adult↗

Follow-up study in congestive (dilated) cardiomyopathy.

A follow-up study was carried out in 98 patients with congestive cardiomyopathy using clinical data and M-mode echocardiography. 59 patients survived (mean follow-up period 18 months), 39 patients died (mean survival period 12.6 months). Median survival time was 3 years. Prognosis was unfavorably affected by ECG signs (left bundle branch block, atrial fibrillation, ventricular premature beats), functional class 4, and left ventricular dysfunction presented by mitral E-point separation over 25 mm, left atrial dimension of 50 mm or more and posterior wall systolic thickening less than 50%. Age, excessive alcohol intake, left ventricular enddiastolic dimension or wall thickness did not affect prognosis. M-mode restudies preformed in 59 patients included a variable course within 2 years after first presentation but a progressive impairment of left ventricular function in mor than 2 years of follow-up.

Adolescent↗

Mural thrombus in left ventricular aneurysm: incidence, role of angiography, and relation between anticoagulation and embolization.

One hundred consecutive patients undergoing left ventricular aneurysmectomy were reviewed to determine the incidence of associated mural thrombus, the accuracy of angiography in detecting thrombus, and any effect of anticoagulant therapy on the incidence of thrombus and embolism. Thrombus was present in 48% of cases and was located in antero-apical aneurysms in all but two cases. Angiography resulted in correct diagnosis of thrombus with a sensitivity of only 31% and a predictive accuracy of 54%. Presence of mural thrombus correlated inversely with duration of anticoagulant therapy. Embolism occurred in 5% of patients with left ventricular aneurysm.

Adult↗

Aortic root motion for the assessment of left ventricular function in acute myocardial infarction.

In a group of patients with various cardiac disorders positive correlation between aortic root motion amplitude and stroke volume was observed: (y=3.41 + 0.061 chi, r=0.719n=27), where y is the aortic wall motion amplitude in mm and chi is the stroke volume in ml. During the serial investigation of 40 patients with acute myocardial infarction aortic root systolic motion amplitude was significantly different between patients groups, selected by the categories of Killip (1967). Biggest amplitudes were found in patients with complicated course, smallest amplitudes in cardiogenic shock. Aortic root systolic motion increased in a parallel direction with the clinical improvement of the patients. Aortic root echos are easily detectable, independent from segmental dysfunction, therefore useful in monitoring of left ventricular function of patients with acute myocardial infarction.

Acute Disease↗