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Biomedical subjects

M Knoke

Publications and source records attributed to M Knoke.

At least 73 records · Page 4Linked to original sources
PubMed1977

[Results of oral methionine loads in normal subjects and patients with liver diseases using an analyzer short program].

Control subjects and patients with liver diseases (cirrhosis, fatty liver) were given an oral methionine load with 100 mg L-Met/kg body weight. Amino acid chromatography was made by a short-program particularly suitable for the diagnosis of hereditary disorders of methionine metabolism. Met-tolerance in blood plasma as well as cystathionine, homocystine and the mixed disulfide homocysteine-cysteine in plasma and urine were investigated. Methylmalonic acid excretion in the urine was determined by gas chromatography. Patients with liver diseases showed some pathological changes of methionine tolerance after the load. However, cystathionine and homocysteine could not be demonstrated. No methylmalonic acid excretion occurred in normal subjects and patients with liver diseases after the methionine load.

Adolescent↗
PubMed1976

[Intestinal microbial flora and resorption].

An abundant microbial growth in the small intestine is called "overgrowth syndrome". The dysbiosis existing hereby is to be characterized by the prevailing of certain sorts of germs. A series of typical symptoms is explained by the metabolic activity of microorganisms, in which case disturbances of absorption are uppermost. Morphological and histochemical changes of the intestinal mucous membrane as well as disturbances of the bile acid metabolism and the absorption of carbohydrates, fats and vitamin B12 are explained. Finally the author deals with the microflora in conditions of malabsorption.

Animals↗