Monitoring of tissue perfusion and cellular function.
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Biomedical subjects
Publications and source records attributed to M Kessler.
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Barroom patrons consumed their drinks in significantly less time and with fewer sips than subjects observed in a laboratory. The former most often drank beer while the latter preferred mixed drinks.
The pO2-multiwire electrode measures the intercapillary oxygen tension. The pO2 histogram, which results from such measurements gives precise information about the question as to whether microcirculation is disturbed or not. Thus, pathological changes in respiration and volume can be recognized earlier than with classical methods. The latter registers the mainly central variables which are compensated for a longer period of time. The local pO2 measurement allows individual regulation of respiratory therapy and monitors the response of oxygen therapy. Using this method oxygen deficiency as well as overdosage of oxygen supply can be averted. Thus, important diagnostic and therapeutic indications can be identified.
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The routine therapy of metastasizing mammary carcinoma at the present time is reported. The course of the treatment is considered in every case in connection with the mental problems of the patient which are partly caused by the often drastic treatment measures carried out. The methods of local radiation therapy, which is combined with ablative hormonal methods or, in cases of progressive metastasization, with added exogenous hormones, estrogens, androgens or anabolics, is explained in detail. The final part of the paper is devoted to the currently used polychemotherapy which replaces the hormonal methods in progressive metastasization.
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