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Biomedical subjects

M Kamiya

Publications and source records attributed to M Kamiya.

At least 181 records · Page 10Linked to original sources
PubMed1986

[Bladder carcinoma with sarcomatous changes].

A 78-year-old man underwent surgery to remove a bladder tumor. The bladder contained two solid pedunculated tumors, which existed independently. Histopathologic examination revealed that of most the tumor was composed of spindle-shaped sarcomatous tissue sometimes containing multinucleated giant cells. Transitional cell carcinoma (Grade 3) was also found at the stalk of the tumor with squamous metaplasia. The squamous metaplasia, which gradually changed into sarcomatous tissue, was also found at many parts of the tumor, but no definite transition of the transitional cell carcinoma into sarcomatous tissue was noted. Therefore, the sarcomatous change of carcinoma in our case was brought about by way of squamous metaplasia of transitional cell carcinoma. The tumor could be given the diagnosis of so-called "carcinosarcoma". The pathologic significance of "carcinosarcoma" was briefly discussed.

Aged↗
PubMed1986

I-cell disease. A case report and review of the literature.

I-cell disease has been reported by many authors but the electron microscopic findings have been reported only rarely. The patient under study was a female infant with a normal delivery after 38 weeks' normal intrauterine life. She showed the physical findings characteristic of I-cell disease, and the diagnosis was made by the analyses of lysosomal enzymes. The child died at the age of 2 years and 3 months due to respiratory insufficiency. By electron microscopy, various-shaped membrane-bound vacuoles were observed in the cytoplasm of various cells such as hepatocytes, myocardial muscle cells, epithelial cells of the renal glomeruli, proximal renal tubular cells, fibroblasts, and chondrocytes. By histochemical analyses we found that these intracytoplasmic storage vacuoles contained glycosaminoglycan and proteoglycan.

Astrocytes↗
PubMed1985

Prolonged expulsion of adult Trichinella spiralis and eosinophil infiltration in mast cell-deficient W/Wv mice.

Eosinophil infiltrations were observed in the intestine and the muscle of both Trichinella spiralis-infected (WBxC57BL/6)F1-W/Wv mice and their littermates, WBB6F1-+/+, +/W, +/Wv, almost to the same extent. W/Wv mice did not show infiltration of subepithelial mast cells and globule leucocytes in response to T. spiralis infection. Increased numbers of these cells were observed in their littermates. Worms in W/Wv mice were retained for longer periods than those in littermates. Also, no difference was noted in the production of specific serum antibodies between W/Wv mice and their littermates, as determined by passive cutaneous anaphylaxis (PCA) for specific IgE and by indirect haemagglutination (IHA). These results suggest a possible participation of SMC, GL and eosinophils in the expulsion of adult T. spiralis.

Animals↗
PubMed1985

Gestation period of the laboratory reared volcano rabbit (Romerolagus diazi).

The period of gestation of the volcano rabbit (Romerolagus diazi) was measured. Females were cohabited within one hour after confirmation of coitus or were separated from the males after cohabiting overnight. In 12 females which gave birth 20 times in total, the gestation period was 39 days in 35%, 40 days in 50% and 41 days in 15%; 85% of animals showed a gestation period of 39 or 40 days.

Animals↗
PubMed1984

Expulsion of Trichinella spiralis from the intestine of W/Wv mice reconstituted with haematopoietic and lymphopoietic cells and origin of mucosal mast cells.

The involvement of haematopoietic and lymphopoietic cells in the expulsion of Trichinella spiralis from the intestine of mice, and the origin of the subepithelial mast cells (SMCs) and the globule leucocytes (GLs) were determined using SMC- and GL-deficient WBB6F1-W/Wv and WCB6F1-S1/S1d mice. On day 12 after infection with T. spiralis, SMCs and GLs appeared in W/Wv mice injected with spleen and bone marrow cells from normal +/+ mice, but not in W/Wv mice injected with thymus, mesenteric lymph node and Peyer's patch cells from +/+ mice or in S1/S1d mice injected with spleen cells from normal mice. On day 22 after infection, GLs and SMCs with giant granules were found in W/Wv mice injected with spleen cells of C57BL/6J-bgJ/bgJ mice in which GLs and SMCs contained giant granules. These results suggested that the precursor cells of SMCs and GLs were located in the haematopoietic tissues. In W/Wv mice reconstituted with SMCs and GLs, expulsion of T. spiralis from the intestine was as rapid as that of the normal mice, but in W/Wv mice injected with lymphopoietic cells and S1/S1d mice which had been injected with normal spleen cell, expulsion of T. spiralis was less rapid. The result suggested that haematopoietic cells containing SMC- and GL-precursor cells might be involved in the expulsion of T. spiralis from the intestine of mice.

Animals↗