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Biomedical subjects

M Franz

Publications and source records attributed to M Franz.

At least 163 records · Page 9Linked to original sources
PubMed1982

Scanning electron microscope study of adult Brugia malayi.

The fine structures of the surface of Brugia malayi obtained from Mastomys natalensis are demonstrated by scanning electron microscopy. The head of the parasite is bulbous in shape. The amphidial openings lie beside small elevations. The surface structure of the inner papillae is smooth with a small elevation in the middle. The outer papillae are grooved. the cuticular annulation in the midbody region of the female worm is narrower than that of the male cuticle. In the posterior region of the female worm there are tubercles and in one worm a lateral papilla was found near the anus. In both sexes the inconspicuous phasmidial openings are situated in a lateral position close to the caudal tip. In the posterior region of the male worm there is an area with tubercles, the area rugosa and numerous perianal and caudal papillae, which vary in their number and distribution. The surface structures are very similar to those of Brugia pahangi.

Anal Canal↗
PubMed1982

The fine structure of adult Onchocerca volvulus. I. The cuticle, the hypodermis and the muscle cell of the male worm.

The fine structure of the cuticle, the hypodermis and the muscle cells of five male worms from Liberia and of two male worms, at least five years old, from Upper Volta is described. The cuticle in the lateral regions is thicker and consists of more layers than in the dorsal and ventral regions. The innermost zone of the hypodermis contains a wide labyrinth of extracellular clefts. The muscle cells are of the shallow coelomyarian type. Bacteria were found in the hypodermis of worms from Liberia and Upper Volta. The hypodermis and the muscle cells contained various other inclusions and particles. Some of them were formed by aggregations of regularly arranged membranes and lamellae. Although all the worms had been alive at the moment of fixation, severe degenerative alterations of the hypodermis and the muscle cells could be observed. Only the cuticular morphology was more or less constant in all seven worms.

Animals↗
PubMed1982

The fine structure of adult Onchocerca volvulus. II. The intestine and the reproductive system of the male worm.

The morphology of the gut and the genital duct of five male worms from Liberia and two male worms at least five years old, from Upper Volta are described. The lumen of the intestine can be distended vesicularly or it can be reduced to a cleft which is filled with microvilli. The intestinal epithelium contains concentric spherules or dense bodies with piles of lamellae. In parts of the intestine of a live worm the cells can be completely disintegrated. The wall of the testis consists of a squamous epithelium which contains numerous dense bodies on the luminal side. The wall of the vas deferens is a squamous or cuboid epithelium which contains glycogen and various particles. In the ejaculatory duct the epithelial cells are linked together by desmosomes at their luminal side. The brownish appearance of some organs under the light microscope is related to the accumulation of iron containing particles.

Animals↗
PubMed1981

The dietitian: a key member of the diabetes team.

For diabetes management and education to be effective goals should be set by a team of health professionals with the input and cooperation of the individual with diabetes. The dietitian needs to be an active member of the team. To participate effectively, the dietitian must be knowledgeable not only about nutrition and food but also about the total diabetes management program. The systems approach of assessment, planning, implementation, and evaluation can then be used for effective nutritional counseling. This approach will provide the dietitian with the means to apply her special skills and knowledge.

Counseling↗
PubMed1980

Simultaneous recording of monophasic action potentials and contractile force from the human heart.

Cardiac monophasic action potentials (MAPs) and contractility have been simultaneously measured in man while the heart rate was being changed by right atrial pacing. A new non-suction electrode was used for safe and long-term recording of MAPs from the endomyocardium. Abrupt changes in cycle-length were followed first by a fast, then a slow response in the adaptation of MAP-duration and of contractility (LV dp/dt max) to the new steady state. After increasing the heart rate then slow phase of MAP shortening appears to be related to the slow staircase of contractility, whereas after the step decrease of frequency no such a relation could be observed. The consistency of these results with those obtained in corresponding in-vitro experiments indicates that this methodical approach may be suitable for assessing the process of E-C coupling in the human heart.

Action Potentials↗
PubMed1980

Scanning electron microscope study on larvae of Wuchereria bancrofti from the vector and from experimental rodent hosts.

The surface structures of larvae of Wuchereria bancrofti from Liberia were examined by scanning electron microscopy. For this study microfilariae from man, first-stage, second-stage, and third-stage larvae from the vector Aedes aegypti, and fourth-stage larvae from the experimental rodent hosts Mastomys natalensis and Meriones unguiculatus were available. From these larvae the structure of the anterior ends, the cuticle in the midbody regions, and the posterior ends are presented. As an obvious structure at the anterior end of the microfilaria and the first-stage larva there is a cephalic cap with a hook on its left side. Three spines are found on the right side close behind the border of the cap. The amphidial openings are found immediately beside the cephalic cap. A simply formed oval mouth is found in the second-stage larva. A small elevation is situated on each side of the mouth. On the anterior end of the third-stage larva there are eight papillae. The four outer papillae are round, the four inner papillae are cone-shaped. The caudal extremity of this larva carries three characteristic bubble like papillae. The mouth of the fourth-stage larva from the experimental rodent host is surrounded by an oral field. The cephalic papillae are indented and the amphidial openings are associated with papillary protuberances. The cuticle of these larvae is regularly annulated. On the caudal extremity, the dorsal papilla is reduced.

Aedes↗
PubMed1980

Electron microscope study of the cuticle of male and female Onchocerca volvulus from various geographic areas.

Male and female Onchocerca volvulus from Liberia, Upper Volta, Tanzania and Guatemala were examined by scanning and by transmission electron microscopy. In the cuticle of the female a basal, a median and a cortical layer can be differentiated. The outer limitation of the cuticle is an irregularly folded surface membrane. Excluding the anterior region the entire cuticle of the worm is covered by a coat. A regular fine honey-comb structure of the surface is found in the anterior region of the female. The morphology of the mouth, the amphidial openings, the papillae and the vulva, as well as the anus and the phasmidial openings, are presented. The cuticle of the male is also composed of a basal, a median and a cortical layer. The surface membrane shows a regular honey-comb pattern, which covers the entire worm with the exception of the anterior and posterior ends, but no coat was found. The cephalic region looks like that of the female. Papillae are arranged around the anus and the caudal tip. The variability of these papillae regarding their number and distribution is presented. The type of the two spicules and of the canal of the longer one is illustrated. The comparison of the worms from Liberia, Upper Volta, Tanzania and Guatemala revealed no morphological differences. Groups of males were examined statistically for differences of the distribution of the posterior papillae, but no geographical differences could be proven.

Animals↗
PubMed1979

Some observations on onchocerciasis including sowda in the Yemen Arab Republic.

A pilot study on onchocerciasis and sowda was carried out in the south-western region of the Yemen Arab Republic. Of 61 persons examined in eight villages 35 (= 57%) were found positive for microfilariae by the skin-snip method, 13 had typical manifestations of sowda, 17 had other onchocercal-suggestive skin lesions and five had subcutaneous nodules. A single larva of Simulium damnosum s.I. was collected in Wadi Barakani. Numerous larvae and pupae of S. ruficorne and S. hargreavesi were taken in fast-flowing streams in four localities. The examination of microfilariae and adult worms by scanning electron microscopy as well as the histochemical staining of microfilariae for the demonstration of acid phosphatase activity confirmed that the concerned filaria belongs to the species Onchocerca volvulus. No morphological differences could be detected between the smaller number of the examined worms from the Yemen and the extensive parasite material from Liberia, West Africa.

Adolescent↗
PubMed1977

Behavior of leucocytes and colony-forming units (CFU-C) in blood of chronic uremic patients during hemodialysis and hemodiafiltration.

In a comparison of the effects of hemodialysis and diafiltration, we found that the transient decrease of circulating granulocytes seen in hemodialysis did not occur during diafiltration. We assume that this is the consequence of effective removal of a humoral leucotoxin by hemofiltration. The CFU-C changes observed parallelled the alterations in the granulocyte count both in hemodialysis and in hemodiafiltration.

Adult↗
PubMed1975

Muscle receptors with group IV afferent fibres responding to application of bradykinin.

In 60 anaesthetized cats the discharge characteristics of single group IV afferent fibres from skeletal muscle at rest, during local mechanical stimulation of the muscle, and in response to injections of bradykinin have been studied. 250 group IV fibres from the gastrocnemius-soleus muscle have been identified by their conduction velocity. Of these fibres 121 have been recorded from the dorsal root and 129 from the muscle nerve. A resting discharge was present in 52% of the dorsal root fibres and in 57% of the fibres recorded peripherally. Out of 203 units subjected to local mechanical stimulation of the muscle 9 responded to light, innocuous pressure; 129 fibres required strong, presumably noxious stimulation to be excited. The rest of 65 fibres could not be activated by the mechanical stimuli used. Intraarterial injection of bradykinin excited 88 out of 184 group IV fibres. Intramuscular injection of bradykinin was also found to be an effective stimulus. External application of bradykinin to the intact and to the dissected muscle nerve regularly had no excitatory effect on fibres being sensitive to intraarterially administered bradykinin. Injections of vasoactive drugs (nylidrine, noradrenaline) failed to affect the activity of group IV fibres responding to bradykinin. It is concluded that bradykinin is a potent stimulant for the intramuscular endings of afferent group IV fibres; the effective concentration lying within the range observed in pathologically altered tissues. This sensitivity to bradykinin together with a high mechanical threshold suggests that muscular group IV afferent units participate in the reception of muscular pain.

Animals↗