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Biomedical subjects

M Eriksson

Publications and source records attributed to M Eriksson.

At least 487 records · Page 27Linked to original sources
PubMed1976

The bioavailability of oral penicillin V. A comparative study of the absorption of different salts of penicillin V in children.

Different salts of penicillin V (pc-V): potassium pc-V (Calciopen and Kåvepenin), calcium pc-V (Penicals) and benzathine pc-V (Meropenin) were given to 37 children (age 2 months to 4 years) with upper respiratory infections. The gastro-intestinal absorption of the drug given in a mixture was followed for three hours after administration by determination of the serum levels from capillary samples. Administration of the mixtures containing the potassium pc-V resulted in a more rapid absorption and in significantly higher plasma concentrations at 30 min than did administration of the preparations containing the calcium and benzathine salts. In four children with coeliac disease, verified by intestinal biopsy, the absorption of potassium pc-V (Calciopen) was compared with that of calcium pc-V (Penicals). A decreased absorption was found and this was most pronounced when the calcium salt was given.

Calcium↗
PubMed1976

The intravenous infusion of co-trimoxazole in cases of septicaemia: tolerance and results of treatment.

The tolerance to co-trimoxazole given by intravenous infusion was investigated in 25 patients suspected to be suffering from septicaemia. One patients developed allergic skin manifestations and two had increased difficulties with cardiac insufficiency, probably on account of the infusion. The other patients tolerated well. The results of treatment of 11 patients with septicaemia were good in 8 cases. In 2 cases, the poor results of the treatment can be explained by the presence of undrained abscesses in these patients. Good concentrations of the components in the serum were achieved by the treatment.

Adolescent↗
PubMed1975

Case report: septicaemia due to Yersinia enterocolitica in a non-compromised host.

A case of septicaemia due to Yersinia enterocolitica serotype 3, biotype 4, in a non-compromised host is described. The patient showed severe signs of gram-negative septicaemia. Treatment with sulphamethoxazole-trimethoprim (Bactrim) was unsuccessful in spite of full sensitivity, bactericidal and synergistic effects in vitro. Tetracycline gave full restitution.

Aged↗
PubMed1975

Influence of diarrhea on the oral absorption of penicillin V and ampicillin in children.

Oral ampicillin and penicillin V was given to 23 and 42 children, respectively, with upper respiratory infections. The absorption of the drugs was followed on one of the first days of treatment for 3 hours after administration by taking capillary samples and determining the serum levels. Approximately 60% of the children were tested for oral absorption during convalescence, 6-8 days after the initiation of the treatment. Diarrhea was evident in more than 60% of the children during treatment with both ampicillin and penicillin V. Diarrhea of short duration did not have influence on the absorption of the antibiotics. Only when persistent diarrhea over the whole therapy period existed, absorption of penicillin V was decreased.

Administration, Oral↗
PubMed1973

Drugs and pregnancy.

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Abnormalities, Drug-Induced↗