A comparison of identical twins in relation to three dental anomalies: multiple supernumerary teeth, juvenile periodontosis, and zero caries incidence.
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to M Berg.
Explore the source record for details and available documents.
The calcitonin secretion from the thyroid C-cells was studied with a peroperative method. The calcitonin concentrations in thyroid venous effluent and peripheral veins were determined in patients who underwent operations because of thyroid and parathyroid disease. In normocalcemia the thyroid vein level of calcitonin was significantly higher than that in peripheral vein. In chronic hypercalcemia no gradient over the thyroid was demonstrable. After injection of pentagastrin into a thyroid artery a very pronounced, but transient, increase in calcitonin concentration was registered. No difference in peak value between normo- and hypercalcemia was demonstrable. The peripheral vein level was unchanged. The peroperative method is very sensitive. A marked peak in thyroid vein corresponds to unchanged values in peripheral vein. The method invites further studies with other secretagogues and receptor-blocking substances.
The 17 cases of sudden deafness in children and juveniles treated in the HNO-Universitäts-Klinik Erlangen between August 1977 and December 1980 are analyzed and correlations of symptoms and possible etiologies are discussed. There is no unique clinical picture. Vascular reasons do not play an important role contrary to adult patients. Unexpectedly viral infections are not of great importance. Young patients who had a sensorineural hearing loss prior to the sudden deafness seem to have a bad prognosis for therapy. Vestibular involvement seems to be of no meaning for a successful therapy in children and juveniles.
The psychic structure of 30 patients suffering from sudden deafness and of 35 patients suffering from otosclerosis was tested by the FPI. Additionally the intelligence was tested by the MWT-B. It could be shown that deafness on one ear does not cause any significant change of personality. Patients with sudden deafness and additional organic diseases did not show any psychic changes or these changes are due to a basic disease. Patients suffering from idiopathic sudden deafness can be differentiated into two groups: the first group consists of patients with no psychic disease; these patients show a good recovering tendency from sudden deafness. The second group consists of patients with a slightly neurotic personality which is in full accordance with those of psychosomatic patients. In these case the organic therapy did not lead to recovery.
In a series of 390 cases with suspicion of acoustic neurinomas 78 such tumors could be diagnosed, including 12 early stage neurinomas. This relatively high detection quote of small neurinomas is due to a special diagnostical programme: Every patient with unilateral and sensorineural hearing loss, independent of vertigo anamnesis or of the result of x-rays must be further examined by a vestibular tests. All 78 patients with acoustic neuroma had pathological vestibular findings. The positional test turned out to be the most sensitive examination in the early diagnosis of acoustic neuromas and yields a still higher incidence than the thermic test: 95% of the patients with a neuroma showed pathological findings in the positional test. Every patient suffering from an unidentified unilateral and sensorineural hearing loss combined with a pathological result in the positional tests must be further checked by a cisternomeatography or computerized tomography using airinsufflation. Every fifth of these patients showed typical signs of an acoustic neuroma in the neuroradiological tests. 68 neuromas are operated today and verified histologically, 10 patients are still waiting for surgical treatment.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Wilson's disease is an autosomal recessive disorder characterized by progressive cirrhosis or neurological signs. Early detection and prompt treatment can reverse the relentless course of the disease. Treatment with D-penicillamine substantially improves the outlook for such patients unless side effects preclude its use. We report the use of triethylene tetramine dihydrochloride (Trien), a new non-sulfhydryl-chelating agent, in a girl who was unable to tolerate D-penicillamine in spite of steroid coverage. The drug has been well tolerated without side effects for approximately 2 1/2 years. Our patient's favorable clinical response would suggest that Trien is a safe alternative agent for the treatment of Wilson's disease when D-penicillamine is not tolerated.
Two groups of pregnant adolescents enrolled in the St. Paul, Minnesota Maternal and Infant Care Project were involved in this study. A retrospective analysis of obstetrical summary sheets of delivered pregnant adolescents was conducted to demonstrate the relationship of the availiability of a comprehensive, interdisciplinary program of prenatal care in a regular public school setting to the achievement of early and continuous prenatal care and to the minimizing of obstetrical complications of the pregnant adolescents who were students in the school. A total sample of 36 students who received prenatal care in the school clinic (study group) from 1973 to 1976 was compared with a random sample of 36 adolescent patients (matched for race) who received care at a non-school clinic (comparison group). The data demonstrated that the study group initiated care earlier and had more total prenatal visits than did the comparison group. Also demonstrated were fewer obstetrical complications in the study group than in the comparison group. The comparison group had more low birth weight infants and more complicated deliveries than did the study group. Therefore, the results of this study support the initial objective and may have significance for educators and health personnel.
Estimation of duration has been shown to be a function of the amount and manner of organization of information processed during an interval. It was assumed that the use of an organizational schema to encode information reduces the actual amount of information stored. It was predicted that the use of an organizational schema will result in relatively shorter estimates of duration. Eighteen undergraduate subjects made estimates of intervals (.58 to 3.0 sec.) during which they watched film animations of moving geometric forms. In a second condition the same subjects were instructed to organize the animation as representing social interaction. An interaction showed that the use of an organizational schema to encode information resulted in smaller estimates for the longer intervals.
Explore the source record for details and available documents.
The auditory nerve of five cats was sectioned unilaterally. Its proximal stump was immediately sutured to the proximal stump of the simultaneously severed facial nerve to study afferent sensory nerve regeneration. After time intervals of nine to 18 months, the nerve anastomosis was tested by electrical stimulation of the anastomosis and by recording evoked cortical responses at the auditory cortex. Electrophysiologic evidence of both fiber regeneration within the sectioned auditory nerve and of the reestablishment of a functional synapse at the cochlear nucleus was obtained. Further support of the concept of a possible auditory nerve grafting was added by the histologic examination of the nerve anastomosis and of the cochlear nuclei, which showed signs of the outspreading of axons from the facial nerve through the auditory nerve and through the barrier of the brain stem into the areas of the cochlear nuclei.
An analytical procedure for the simultaneous determination of pethidine and norpethidine in plasma by selected ion monitoring is described. The method has a capacity of 15--20 analyses per hour and can be used to determine pethidine and norpethidine down to 25 ng ml(-1) and 5 ng ml(-1), respectively. The selected ion monitoring method has been compared with a method based on electron capture detection after analysis of pethidine and norpethidine in spiked plasma samples and in plasma from patients. The two methods are capable of performing selective and accurate determinations of pethidine and norpethidine, in the concentration ranges obtained in man after a single therapeutic dose of pethidine.
Explore the source record for details and available documents.
A device consisting of a hearing protector headset and a modified hearing aid is used as a protective hearing aid for normal hearing subjects. Understanding of sufficiently redundant speech is remarkably improved, especially for noise level of about 20 dB above speech level. Tests have been made with the "Freiburger Zahlentest" and amplified "party noise" up to noise levels of 105 dBSPL. As an example: the above mentioned device enables the wearer to understand speech of 85 dB with 105 dB loud speech similar background noise while still the ears are charged with no more than 90 dB at all. Application for hyperacusis and recruitment patients is discussed.
The acetylation of procainamide and sulfadimidine has been measured simultaneously in plasma and urine in 20 healthy human volunteers by a specific G.L.C. method, after single and multiple oral dral doses of procainamide retard tablets. A distinct bimodality (9 rapid and 11 slow acetylators) was apparent from the concentrations of procainamide and N-acetylprocainamide both in urine and plasma, which was in complete agreement with data about sulfadimidine acetylation. The influence of acetylator phenotype on the relative concentrations of procainamide and N-acetylprocainamide in plasma as cn 5 additional healthy subjects after a single oral dose of procainamide. The present results show that acetylator phenotype can now be determined using procainamide as the test substance, and for this purpose multiple doses offer hardly any advantage over a single dose of the drug. However, because the separation between rapid and slow acetylators is less pronounced for procainamide than for sulfadimidine, precise criteria must be established for the conditions of the test, and the influence of diseases, such as renal insufficiency, should be taken into consideration.
Explore the source record for details and available documents.