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Biomedical subjects

M Adloff

Publications and source records attributed to M Adloff.

At least 109 records · Page 6Linked to original sources
PubMed1980

Electrosurgery and wound healing: an experimental study in rats.

Many surgeons are hesitant in the use of electrocautery on the gastrointestinal tract. The aim of the present study is to compare wound healing following incisions made by scalpel and diathermy in the rat. Healing was assessed by bursting strength measurements and histology. This study revealed no difference in strength by bursting measurements between scalpel and diathermy incision. Histologically there is not a lag in healing in the gastrointestinal tract following electroincision. It is concluded that in abdominal surgery, diathermy can be used without detriment to the strength of any suture line and with no difference in its final healing.

Animals↗
PubMed1980

[Papillary and adenomatous polyps of the gallbladder. Clinical, radiological, and anatomical study, and report on 6 cases (author's transl)].

Papillary and adenomatous polyps of the gallbladder are frequently confused with cholesterol pseudotumors. They are rare tumors and are usually diagnosed only after histological examination of a specimen removed at operation. Their course is uncertain and they are potentially malignant lesions, as shown by one of these cases. The frequent association with lithiasis, which in fact can induce malignant changes, is a point in favour of the need for surgical therapy.

Aged↗
PubMed1980

[Mechanical sutures in digestive tract surgery: preliminary results (author's transl)].

Intestinal sutures decompose by means of a series of regular steps which can be replaced, from the efficacy, regularity, and rapidity points of view, by a mechanical process. Employing a mechanical suture constitutes a new aspect of digestive tract suturing which requires preliminary training in the use of the method, as strict rules must be followed if a catastrophy is to be avoided. The authors have used different forceps (T.A., G.I.A., and E.E.A.) since 1977, and report the results obtained in 438 patients, including 237 operations for closing visceral sections and 354 anastomoses of all types. An analysis of these results confirms the feasibility and immense value of this new suturing technique.

Digestive System Surgical Procedures↗
PubMed1980

[Comparative study on anastomotic surfaces obtained after using mechanical suture in digestive surgery (author's transl)].

The authors studied the theoretical values of the anastomotic surfaces obtained after using mechanical suture clips of American origin in digestive surgery. The EEA clip enables circular anastomoses to be obtained immediately. The anastomotic surface is defined by the capsule used, whatever the diameter of the digestive tube. The TA clip determined, by using the triangulation principle, anastomoses that have a tendency to become circular. The anastomotic surface varies as a function of the digestive tube diameter and may reach much higher values. With the GIA clip, laterolateral anastomoses can be obtained which are complete by closure of the outgoing orifice of the apparatus. Large variations in anastomosis surface are obtained according to the method used to close the orifice. This study supplies a new aspect of mechanical sutures. It gives the surgeons, who agrees with this suturing method, a supplementary element of choice for the anastomotic procedure.

Biophysical Phenomena↗
PubMed1980

Prethoracic omentopexy in rats with experimentally induced portal hypertension.

The effectiveness of prethoracic omentopexy was tested in an experimental study performed upon rats. Cirrhosis was induced by injecting carbon tetrachloride three months before the omentopexy procedure. Biochemical effects were studied together with sequential measurements of portal vein pressure and portograms before and after omentopexy. The procedure provides significant portal decompression by the 15th postoperative day with the presence of functioning portosystemic communications between the omental and internal mammary veins.

Animals↗
PubMed1979

[Intestinal polyposis (author's transl)].

Recto-colonic polyposis is typical of pre-malignant lesions. Recognition and the application of appropriate treatment offer true prophylaxis against recto-colonic carcinoma in sufferers. Careful study should be made of other family members, the only way in which latent forms may be discovered before the stage of malignant change.

Colonic Neoplasms↗
PubMed1979

Primary carcinoma of the gallbladder: review of 25 cases.

The records of 25 patients with carcinoma of the gallbladder occurring during a 5 year period were reviewed. The frequent relation of the disease with cholelithiasis and benign tumors has been widely recognized. Stones were present in the gallbladder in 92 per cent of the patients. In the majority of cases, a diagnosis of carcinoma of the gallbladder was not made clinically. The most common preoperative diagnosis was benign biliary tract disease. The mean survival time after operation was 7 months, and only five patients had a curative resection. The best hope for reducing the mortality from this disease lies in earlier cholecystectomy in patients with benign gallbladder disease.

Adenocarcinoma↗
PubMed1979

In vivo exploration of the tensile strength of the abdominal wall after repair with different prosthetic materials. Experimental study in the rat.

The problem of parietal herniation seems to be a simple mechanical one for which there should be a safe method of repair. In the present study, the bursting strength of abdominal wounds was explored by mechanical investigation and the repair process evaluated at a cellular level by quantitative microscopy. Both methods of investigation show that mesh materials have advantages over nonporous cloth materials in the repair of large defects of the abdominal wall.

Abdominal Muscles↗
PubMed1979

Evaluation of the biliary excretion of pencillin G.

Biliary excretion of penicillin G was studied experimentally by perfusion of isolated rabbit liver. Under these conditions, bile recovery accounted for 5% of the amount of penicillin G added to the perfusing blood (10 mg). In man, after intravenous administration of a 599-mg dose of penicillin G (1,000,000 U) to patients provided with T-tube drainage (n = 10), the maximum biliary level averaged 18.0 +/- 8.0 microgram/ml at 2 h; biliary recovery of penicillin G accounted for 0.12% of the administered dose. The excretion of penicillin G in the juice collected through duodenal tubing in normal subjects averaged 0.07% of the administered dose. Peroperative assays showed that the concentrations determined 1 h after intravenous administration 599 mg of the drug attained 45.7 +/- 16.7 microgram/ml in the gallbladder bile and 93.5 +/- 16.3 microgram/ml in the common-duct bile.

Animals↗
PubMed1979

[Interest and limits of estimation of the carcinoembryonic antigen in colonic and rectal (author's transl)].

An attempt is made to define the usefulness and limitations of carcinoembryonic antigen (CEA) radioimmunoassay for evaluation of diagnosis, tumor resection and detection of tumor relapse in 108 patients with colorectal carcinoma. Preoperative CEA levels were correlated with pathological stage and tumors localisations. Increasing levels of CEA were found with advanced stage of disease (Stage C and D lesions). Our results indicate: 1) that an incomplete drop in circulating CEA level one month after surgery was a bad prognostic sign; 2) that relapses of colon and rectum carcinoma can be detected by increased CEA levels months before the appearance of any clinical evidence.

Carcinoembryonic Antigen↗
PubMed1978

The posterior approach for villous tumors of the rectum. Report of eleven cases.

Use of the posterior surgical approach for the management of villous adenoma of the rectum below the peritoneal reflection has been evaluated in eleven patients. There has been no mortality and no recurrence. The Kraske approach was also suitable in four patients with noninvasive adenocarcinoma arising within villous adenomas, although there is no place for this procedure in the treatment of invasive carcinoma.

Adenocarcinoma↗