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Biomedical subjects

L Janzon

Publications and source records attributed to L Janzon.

At least 199 records · Page 11Linked to original sources

Radiographic patterns of the mammary parenchyma: variation with age at examination and age at first birth.

Mammograms of 15,110 women, representing a random selection of all 45-69-year-old women living in Malmö and taking part in screening for carcinoma of the breast, were analyzed using Wolfe's criteria for variations in the parenchymal pattern with (a) age at examination and (b) age at the birth of her first child. P2 and DY, which are considered high-risk patterns, increased in frequency with advancing age at first birth, being highest in nulliparous women, but decreased with age at examination.

Adult↗

The arm-ankle pressure gradient in relation to cardiovascular risk factors in intermittent claudication.

The arm-ankle systolic pressure gradient was measured in 165 male patients with intermittent claudication and was correlated with different combinations of known cardiovascular risk factors. The pressure gradient increased with increasing number of risk factors. We conclude that intermittent claudication may be used as a simple model for studies of arteriosclerosis, the arm-ankle systolic pressure gradient being a measure of the degree of arteriosclerosis between heart and ankle.

Adult↗

Wrist ganglia. Incidence and recurrence rate after operation.

165 patients operated on for primary wrist ganglia during 1970-71 were followed-up 5 years later in order to study the recurrence rate after a standardized surgical procedure. A questionnaire was used and the overall response rate was 86%. The recurrence rate was 12.7% and the annual incidence rate was 43/100,000 for females and 25/100 000 for males, giving a F/M sex ratio of 1.7 to 1.

Adolescent↗

Respiratory complications after upper abdominal surgery. The incidence of chest X-ray abnormalities, arterial hypoxemia and clinically recorded pulmonary complications.

The incidence of postoperative chest X-ray abnormalities, arterial hypoxemia and clinically recorded pulmonary complications was studied in fifty-two 40-75-year-old men admitted for elective surgery for peptic ulcer or gallbladder disease. Twenty-eight (54%) patients had an abnormal chest X-ray and twenty-three (43%) arterial hypoxemia, whereas only four patients (8%) were identified with clinical signs and symptoms of respiratory complications. Forty-one patients (79%) were found with pulmonary complications by at least one of the three methods. Twelve patients had both an abnormal chest X-ray and arterial hypoxemia. Only two of these were identified with clinical signs indicating pulmonary complications. The great discrepancy between results based on clinical signs and symptoms noted in the patients' records and results based on postoperative chest X-ray and measurements of the arterial oxygen tension, respectively, should be of great importance when comparing the incidence of pulmonary complications after different forms of surgery and when assessing risk factors and clinical consequences of respiratory complications.

Adult↗

Results of a quit-smoking research project in a randomly selected population.

In the spring of 1973, 58 strictly randomized heavy smokers from a defined population of men born in 1914 were asked to quit smoking, at least for 8-9 weeks, as a part of a research project focused upon the relationship between smoking and peripheral blood flow, fibrinolysis, and lung function. Eighty-eight per cent of the smokers were willing to try to quit smoking. Seven (12%) refused at the outset, as they regarded quitting as impossible. Of the remaining 51 it was possible to keep 31 (60%) free from smoking for 8-9 weeks with the aid of an intense anti-smoking program lasting 6 weeks. Checks of continued smoking abstention were made by questionnaire and COHb-determination. After six weeks, no further information was given to the subjects. A follow-up after 8-9 months revealed that 33% of the 51 participants (i.e. 29% of the original 58) were still non-smokers. The long-lasting effect of our quit-smoking method was equal to the best reported by others and 30% is probably the highest rate of long-term success to be achieved in smoking cessation.

Blood Circulation↗

Smoking and fibrinolysis.

In order to study the fibrinolytic activity of vein walls in smokers and nonsmokers, 71 randomly selected heavy smokers, i.e., smoking more than 15 g tobacco per day, and 41 nonsmokers from the population group "Men born in 1914 residing in Malmo" were invited to undergo a health examination. When examined after 12 hours' abstention from tobacco, the smokers were found to have the same fibrinolytic activity as nonsmokers. Out of the 71 heavy smokers, 31 refrained from smoking during 8-9 weeks (as monitored with questionaire and COHb-determinations). Neither in those who had abstained from smoking nor in the controls did the fibrinolytic activity differ from that initially recorded. In a randomly selected subsample of 19 individuals examined after only one week's abstention from tobacco, the fibrinolytic activity, after venous occlusion of forearms, tended to be lower in the blood as well as in superficial hand veins, but the difference was not significant. The effect of smoking six cigarettes during three hours was measured. This level of smoking was associated with an increased fibrinolytic activity in blood, measured as euglobulin clot lysis time, and in superficial hand veins. This increase is probably due to the combined effects of nicotine and carbon monoxide.

Blood Cell Count↗

Risk factors in peripheral arterial disease. An out-patient pilot study at the Department of Surgery in Malmö.

In a pilot study in patients with verified peripheral arterial occlusion, smoking was compared with hypertension, hyperlipidemia, and glucose intolerance, as a risk factor for peripheral arterial disease. The material consists of 17 men, all new out-patients at the Department of Surgery in Malmö during the first 6 months of 1973. Of these patients, 15 were smokers, all inhaled. Glucose intolerance was found in 4, hyperlipidemia in 3 and hypertension in 2 individuals. It is shown that smoking, glucose intolerance, hyperlipidemia and hypertension are more common in patients with peripheral arterial disease than in defined population groups. In patients with bilateral occlusion an increased number of risk factors was found. Smoking was the most common risk factor and in 10 patients it was the only known risk factor.

Arterial Occlusive Diseases↗