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Biomedical subjects

K Ueda

Publications and source records attributed to K Ueda.

At least 1,261 records · Page 70Linked to original sources

Stability of the mandible after sagittal ramus osteotomy for correction of prognathism.

The change in the position of the mandible after sagittal ramus osteotomy was evaluated on lateral cephalograms and in dental casts in 44 patients with mandibular prognathism. The postoperative relapse of the mandible at four landmarks was less than 1 mm on cephalograms and 1.1 mm at the first molar on the side with the larger posterior movement. The tendency to relapse was greater in cases in which large posterior and/or lateral movements of the mandible occurred at surgery. The importance of proper postoperative care and avoidance of lateral shift of the mandible to minimize relapse is stressed.

Adolescent↗

[Valvular lesions complicating Kawasaki disease: a Doppler echocardiographic evaluation].

Coronary artery aneurysms are the most frequent and important complication of Kawasaki disease, but valvular disease is less frequently observed. During the last three years, we have observed mitral regurgitation (MR) in nine (7.3%), aortic regurgitation (AR) in six (4.6%) and tricuspid regurgitation (TR) in five (4.2%) patients with Kawasaki disease. The diagnosis of valvular disease was confirmed by Doppler echocardiography in all patients. Cardiac murmurs typical of regurgitation were audible in approximately half the patients with MR and AR, and in only one with TR. By chest radiography, cardiomegaly was observed in five of nine patients with MR and in three of six with AR, but in none with TR. Similarly, the ECG finding of cardiac overload was observed in four patients with MR and in three with AR, but in none with TR. Thus, Doppler echocardiography proved very valuable for diagnosing valvular regurgitation in patients with Kawasaki disease. Other cardiovascular complications included coronary artery aneurysms in all except for only one patient with TR. Subsequent myocardial infarction was observed in three patients with MR and in two with AR. Valvular lesions complicating Kawasaki disease generally carry a good prognosis, without progression to stenotic valvular lesions. Although the exact mechanism of this complication is obscure, it is postulated that the valvular lesion results from myocardial infarction or from inflammation of the valvular leaflets or apparatus of the valve following carditis.

Child↗

Hyperbaric oxygen therapy in experimentally induced acute cerebral ischemia.

Effects of hyperbaric oxygen (HBO) on acute cerebral ischemia were studied in spontaneously hypertensive rats, which had the carotid artery bilaterally ligated. The animals were exposed to HBO (100% 02 at 2 ATA) for 30 min at 1 or 3 h after carotid ligation (treated group). Survival time and brain tissue metabolites were measured after HBO in these animals and compared with ischemic animals without HBO exposure (nontreated group). The animals treated at 3 h after ligation survived longer (6.5 +/- 0.7 h) than did nontreated ones (4.3 +/- 0.2 h) (P less than 0.05). The cerebral lactate increased much less in these treated animals (24.60 +/- 1.67 mM/kg) than in nontreated ones (31.78 +/- 1.68 mM/kg) (P less than 0.05). Cerebral ATP levels tended to decrease less in the former (0.66 +/- 0.17 mM/kg) than in the latter (0.59 +/- 0.07 mM/kg). When HBO started at 1 h after carotid ligation, however, there were no significant differences of survival time or brain metabolites between treated and nontreated groups of animals. The present results indicate that HBO administered at 3 h after brain ischemia prevents further increase in cerebral lactate and produces a slight but significant increase in survival time.

Adenosine Triphosphate↗

[Clinical investigations on prostatic carcinoma patients who survived for long periods].

A clinical investigation was conducted on 15 prostatic carcinoma patients who survived for more than 3 years (as of October, 1984) since the initial examination. The patient's age at first examination ranged from 56 to 84 years, and survival time was from 3 to 8 years. There was no correlation between age at first examination and survival time. No statistically significant relationship was found between the initial examination stage and survival time. However, the Stage D group showed a wide-ranging survival time from the shortest to the longest survival time. In the relationship between stage and grade, as cited above, group D reflected multiple aspects of prostatic carcinoma in the broad spectrum observed from Grade 1 to Grade 3. The performance status of the 15 prostatic carcinoma patients was either Grade 0 or 1 at the initial examination. The group classified in Grade 0 at the time of the first examination displayed a more favorable performance status than the Grade 1 group now (P less than 0.05). Regarding the stage variation, 1 patient showed improvement, 12 showed none, and 2 reflected advance of the disease. It is important that radical surgery be indicated in any operable case, and in the inoperable cases long-term control therapy is required.

Aged↗