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Biomedical subjects

K Seidel

Publications and source records attributed to K Seidel.

At least 91 records · Page 5Linked to original sources
PubMed1984

[beta-Phenylethylamine in the cisternal fluid in acute endogenous psychoses].

Beta-Phenylethylamine can be detected in the cisternal cerebrospinal fluid of healthy controls and acute endogenous psychoses. One group of the patients shows the same concentrations as the psychiatrically healthy controls. In the other groups beta-phenylethylamine was found to be elevated in some cases up to a very high level. The results suggest a link between a disturbance of the phenylethylamine pathway and certain endogenous psychoses.

Humans↗
PubMed1983

[Methylated and unmethylated indolamine in the cisternal fluid in acute endogenous psychoses].

Tryptamine (Try), 5-methoxytryptamine (5MeOT), N-methyltryptamine (N-Met), 5-methoxy-N,N-dimethyltryptamine (5MeODMT) and N,N-dimethyltryptamine (DMT) are metabolites of the neurotransmitter 5-hydroxytryptamine (5HT). The cisternal cerebrospinal fluid (CSF) is probably a suitable biological material for investigating the problem of indolamine metabolism in schizophrenic patients. As part of a biological research programme on schizophrenia we have investigated concentrations of cisternal CSF indolamines in a group of acute paranoid patients in comparison with psychiatrically healthy controls. The concentrations of indolamines in the cisternal CSF reveal that psychotomimetic indolamines like 5MeODMT, 5MeOT and DMT and the indolamines N-Met and Try are present in psychological and pathological states. The patients suffering from acute paranoid schizophrenia have high or very high levels of the investigated indolamines in comparison with healthy controls, but there are significant individual differences in the group of these patients. The search for correlations between the level of a single indolamine and individual psychopathological symptoms could provide more specific information for diagnosis or treatment.

Acute Disease↗
PubMed1983

[Communicable disease problems of sewage with special reference to human pathogenic viruses].

Summarizing, it can be said that the epidemiological hygienic risk originating from community waste water can be controlled. This risk appears to be considerably lower when directly handling waste water than indirectly by contact with water contaminated by waste water. The sewage treatment technologies presently in use reduce the contents of viruses, bacteria, protozoa and worm eggs to a varying extent. Owing to the fluctuating concentrations in the inflow to the sewage treatment plant, a proportion of these microbes or proliferation stages of parasitic worms must always be expected not to be eliminated. The pathogens held back in the treatment plant burden primarily the sewage sludge. The various processes of sludge stabilisation influence their number and degree of infectiousness to a varying extent (2, 3, 6). The most important risks of infection which waste water entails, originate from contaminations of raw water and above all of treated drinking water. Statistics from the United States indicate that the above-mentioned bacteria, protozoa and part of the viruses have caused drinking water epidemics (23, 24). Attention has to be paid to bacteria and viruses because some of them prove harmful already in very low doses. Moreover, the occurrence of protozoa should be investigated more intensely. Apart from changes in pathogenicity and low infectious doses, also the fact should be duly considered that these microorganisms are likely to increasingly invade our waste waters, as millions of people yearly head for southern climates. There they fall easily prey to infections which overwhelmingly remain inapparent clinically, and discharge pathogens frequently for a very long period without revealing any symptoms. Also in connection with methods of virus analysis, improved meanwhile the constant efforts for improved indicator systems in the identification of pathogenic organisms must be continued so that epidemiological hygienic problems can be better evaluated and solved.

Bacteria↗
PubMed1982

[Renal phlebographic findings in painless macrohematuria].

After extensive review of literature concerning renal varices including suburothelial phlebectasia three cases of painless macrohematuria are recommended with unusual phlebographic findings: 1. a large renoiliac anastomosis combined with associated varices of the ureter, 2. a wide renohemazygal anastomosis draining nearly totally left renal venous blood into the vena cava superior, simultaneous existing varices of renal pelvis and ureter and 3. a persisting circumaortal ring. It is discussed whether phlebographic revealed renal varicosity is origin of bleeding in any case or bleeding may be caused eventually by associated suburothelial phlebectasia.

Adult↗
PubMed1982

[Virus removal from municipal wastewater by biological sewage treatment].

During a period of ten months, we have determined once a week the amount of viruses in the untreated sewage and in the effluent of two communal sewage treatment plants. Besides, we have compared the virus content of chlorinated and unchlorinated effluent and have determined the amount of viruses in the river in which the effluent is discharged, and in groundwater. In order to concentrate the viruses, the AlCl3-treated samples were filtered through cellulose nitrate filters and the adsorbed viruses eluted with cell culture medium containing 10% fetal calf serum. This medium was used for inoculating cell cultures which were monitored several times weekly for CPE. After the treatment in the plants, the number of viruses was reduced 99.15 and 97.9% respectively. Chlorination of the effluent further reduced the number of viruses by a factor of 5. None of the groundwater samples was viruspositive.

Chlorine↗
PubMed1981

[The indications for neuroradiologic examination methods after the introduction of computer tomography].

In a short survey, empirical values are presented in a comparative assessment of computer-tomographical and conventional neuroradiological examination programmes. The demand for subtle clinical preliminary examinations and systematic establishment of indications is just as true of computer tomography as it is of other instrumental methods. If possible, however, non-invasive examination methods should be given preference.

Brain Diseases↗
PubMed1981

[Effects of computer tomography on the indications and diagnostic strategy in important neurologic disease groups].

The revolutionary nature of the computer tomography requires new strategies in the diagnosis of neurological diseases. Only a differentiated examination plan can promise maximum success. This plan is determined for each indication under consideration of the clinical pictures including its acuity. Non-invasive examination methods including computer tomography are completed by invasive pre-operative examinations.

Brain Injuries↗
PubMed1981

[Comparative studies on the frequency of occurrence of degenerative spinal changes in neolithic, medieval and modern man].

105 judgeable spinal columns of neolithic cultures and 11 skeletons from the 11th and 12th century were examined for the presence spondylotic and spondylarthrotic changes of the spinal column taking into consideration the intensity and frequency of affection. With nearly the same affection per individual the frequency of affection in the neolithic population showed significantly lower values with relatively more frequent changes of the cervical vertebral column of the males and greater changes of the lumbar vertebral column in females. The neolithic and medieval group possess a different dependence on age. Apart from this, the medieval group shows an anticipation of the appearance of degenerative changes by about ten years compared with examinations from modern times. The reasons of these differences are discussed.

Adolescent↗