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Biomedical subjects

K Seidel

Publications and source records attributed to K Seidel.

At least 109 records · Page 6Linked to original sources
PubMed1980

[Extraction of serotonin, bufotenin, 5-methoxytryptamine and 5-methoxy-N,N-dimethyltryptamine and their fluorometric determination with o-phthaldialdehyde].

For the investigated indolamines, the recovery following extraction with n-butanol and acetic acid ethyl ester from alkaline solution amounted to 80-90%. Using benzene only the two 5-methoxyindolamines were transferred from the alkaline medium into the organic phase. The reaction of the o-phthaldialdehyde with substituted indolamines was optimized in regard to higher fluorimetric detection sensitivity. The lower limit of determination was 2.0 ng for 5HT and 5OHDMT, and 1.0 ng for 5MeOT and 5MeODMT.

5-Methoxytryptamine↗
PubMed1979

[Biochemical mechanisms for the effect of alcohol on the brain].

This paper reviews and discusses basic knowledge of biochemical mechanisms of action of ethanol upon the central nervous system, the emphasis being on effects upon cerebral membrane structures and processes as well as mechanisms of chemical synaptic transmission. Results of detailed studies into material and steric changes in membranes, ion-dependent adenosine triphosphatases, variations in ion balance, effects upon cyclic nucleotides, influences on special transmitter systems, and mechanisms of formation of morphine-analogous condensation products are presented. In addition, open questions are derived and formulated in problem complexes.

Acetaldehyde↗
PubMed1979

[Vegetative parameters under the effect of ouabain (g-strophanthin) in endogenous depressive patients. 1. The salivation rate].

In 7 healthy test persons and in 17 endogenous depressive patients the salivations rate was measured in a survey investigation with the SHP-test. The salivation rate of healthy test persons is constant. In endogenous depressive patients it develops a diminishing of depression depth under treatment with Ouabain (g-Strophanthin) between the 6th and the 12th day which is connected with reduction of the drive diminishing and the restauration of mood. The effective salivation rate is gaining. Possible principles of the influence of Ouabain are discussed.

Depression↗
PubMed1978

[Relationship between the unconscious and motivation in establishing a therapeutic program].

The need for complex psychotherapy is reified by using the combination of group psychotherapy with methods of individual and behavioral therapy as an example. The fact that certain forms of maldevelopment cannot be satisfactorily checked by dynamic group psychotherapy alone is considered to be due not only to the conditioning of, and automatism associated with, neurotic malbehavior. It is especially in the case of inordinate dread and fear of disease, which is generally referred to as nosophobia, that the patient's great difficulty in accepting the possibility of a mental origin or causation of his ailment stands in the way of making effective use of such a therapy. The authors are of the opinion that acceptance by the patient of a mental origin or causation is made difficult especially by the fact that in the case of neurotic maldevelopments the kind and degree of neurotic conflictiveness are lore or less unconscious. This fact, which has not so far received much attention, should be taken into consideration in future research into the unconscious.

Behavior Therapy↗
PubMed1977

[Therapy of rheumatic fever].

After making the diagnosis the rheumatic fever as a secondary disease after streptococcal infection is immediately to be treated with penicillin G. Parallel to this or overlapping the rheumatic inflammatory mesenchymal tissue reactions are treated with prednisolone or derivatives, aminophenazone or salicylic acid preparations, in which cases in children prednisolone and aminophenazone are preferred. The combat against the streptococcal infection by means of penicillin transgresses into a recidivation prophylaxis with benzathin-penicillin, which is to be performed up to an age of 5 years. Substitutes for the recidivation treatment with benzathin-penicillin are V-tablopen or erythromycin, perhaps also sulfaclomide. The treatment is to be performed in a hospital up to the time that the patient is free from signs of inflammation and at least 4 weeks without fever, then a gradual rehabilitation begins.

Adult↗
PubMed1977

[Arthropathies in intestinal diseases].

Together with gastroenterologists rheumatologists describe diagnostically significant disturbances of the supporting apparatus and the locomotor system which frequently occur in ulcerous colitis, enterocolitis regionalis Crohn, Whipple's disease and non-tropical sprue. Important conclusion for the diagnostic approach supplement the description.

Adult↗
PubMed1976

[Diagnosis of rheumatic fever].

In a survey the frequent possibilities of the diagnostics of rheumatic fever are described. The rheumatic fever is a general disease on immunological basis caused by an infection with beta-haemolysing streptococci of group A. The disease appears as visceral form (carditis rheumatica, chorea minor) or as peripheral manifestation (acute polyarthritis, erythema anulare, subcutaneous nodules, purpura rheumatica). The diagnostics is essentially based on clinical, physical, biochemical and immunoserological findings on the basis of modified criteria after Jones. Immunological methods for the demonstration of circulating antibodies gain an increasing diagnostic significance.

Antistreptolysin↗