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Biomedical subjects

K Schulze

Publications and source records attributed to K Schulze.

At least 127 records · Page 7Linked to original sources
PubMed1980

[Diagnosis of echinococcosis of the liver by angiography (author's transl)].

Twenty patients with Echinococcus cysticus and 15 with E. alveolaris were studied. Selective upper abdominal angiographies, performed in most of these cases, were reviewed retrospectively for typical angiographic changes. In a large percentage, E. cysticus demonstrated typical cystic and expansive signs; atypical vessels were rarely seen. How the "rim sign" develops is demonstrated. Usual signs of E. alveolaris are incomplete solid and necrotic space occupying lesions, as seen also in malignancy. Although angiography offers a high diagnostic rate in hepatic manifestation of this parasitic disease, it has been superseded today by sonography and computer tomography. It is, however, still a valuable investigation in pre-operative work-up.

Angiography↗
PubMed1979

Multiple adenocarcinomas and premalignant changes in "backwash" ileitis.

In a patient with long-staning ulcerative colitis and "backwash" ileitis, multiple carcinomas developed in the colon and ileum. In both locations premalignant mucosal changes of the basal cell proliferation type were seen adjacent to and remote from sites of carcinoma. Although the frequency of such premalignant and malignant changes in "backwash" ileitis is unknown, their concurrence in this case suggests that ulcerative colitis involving the terminal ileum increases the risk of small bowel carcinoma.

Adenocarcinoma↗
PubMed1979

[Acute aortic thrombosis (author's transl)].

A case of acute thrombosis of the aorta is described; it extended from the superior mesenteric artery to the bifurkation and was probably due to oestrogen medication. The clinical features and diagnosis of this rare condition are described. The condition usually develops against a background of advanced arteriosclerosis and is initiated by certain haemodynamic factors such as intimal damage from blunt trauma, emboli or the thrombogenic effect of oestrogens. The symptoms, such as pain, absent pulses etcetera are the result of ischaemia and depend on the extent of the lesion. A definite radiological diagnosis can only be made by means of aortography, if necessary with oblique projections. The Seldinger technique with a femoral or axillary approach is the method of choice. Aortography shows a filling defect and occasionally a collateral circulation.

Acute Disease↗
PubMed1979

[Apophyseolysis, evulsion fractures and osteochondropathy of the anterior inferior iliac spine (author's transl)].

Evulsion fractures of the anterior inferior iliac spine in adults usually are the result of sudden contraction of the rectus femoris muscle during sporting activities, particularly football. In children, before fusion of the apophysis, there may be an apophyseolysis. This may result in a chondropathy because of abnormal development of the frequently multiple ossification centres. In contrast to the relatively frequent evulsion fractures of the anterior superior iliac spine, such an event is very rare in the anterior inferior iliac spine. Three illustrative cases are described showing the typical combination of history, localisation, pain recurrence during exercise and x-ray changes, which usually consist of a curved osseous structure separate from the iliac bone. These findings permit a correct diagnosis.

Adolescent↗
PubMed1979

[Malignant tumours in horseshoe kidneys (author's transl)].

Hypernephromas were found in horseshoe kidneys in two patients; the diagnostic problems arising from this combination are discussed. Detailed demonstration of horseshoe kidneys by excretion urograms may be poor and tumours may therefore be overlooked and, on palpation, an abnormality within the gastrointestinal tract may be simulated. Angiography usually indicates the diagnosis and helps in planning surgery. Although there is no increase in the incidence of adeno-carcinomas in horseshoe kidneys, there is a significant increase in the incidence of Wilm's tumours and of carcinomas of the renal pelvis. Treatment consists of heminephrectomy or resection of the tumour; complications are relatively common.

Adenocarcinoma↗
PubMed1978

Intussusception of sigmoid colon in an adult. Spontaneous expulsion of sequestered bowel and restoration of bowel continuity.

A 67-year-old white man presented with bloody diarrhea and passed a 22-cm long segment of full-thickness sigmoid colon following a barium enema. He had advanced peripheral and cerebral vascular disease and had undergone pelvic irradiation for a bladder cancer five years previously. He recovered uneventfully from the bowel sloughage. This was apparently due to an intussusception of the sigmoid colon followed by the formation of adhesions between the edges of the adjacent viable bowel.

Aged↗
PubMed1978

[Non-traumatic myositis ossificans circumscripta (author's transl)].

The clinical, pathological and radiological features and the differential diagnosis of the very rare condition of non-traumatic myositis ossificans circumscripta are illustrated by one patient. The characteristic radiological appearances make a correct diagnosis of this localised, non-malignant process possible.

Adolescent↗
PubMed1978

Regional differences in potassium content of smooth muscle from opossum esophagus.

Strips from the proximal part of the smooth muscle segment of opossum esophagus have a significantly higher potassium content (50 +/- 3 meq/kg) than those from the distal part (38 +/- 3 meq/kg). There are no significant differences between the two regions in content of sodium (65 +/- 4 meq/kg in proximal, 71 +/- 3 meq/kg in distal) or chloride (48 +/- 10 meq/kg in proximal, 42 +/- 5 meq/ kg in distal). The mean [14C]inulin uptake is 240 +/- 10 ml/kg in both proximal and distal strips. [14C]polyethylene glycol uptake is smaller and [14C]sucrose and [14C]mannitol uptake in both areas are larger than that of inulin. Intracellular potassium concentration (based on the inulin uptake as an estimate of the extracellular space volume) is significantly higher proximally (71 +/- 3 mM) than distally (52 +/- mM). Ouabain, 10(-4) M, increases the intracellular concentration of sodium and decreases the intracellular concentration of potassium in both the proximal and distal segment. The efflux of 86Rb, measured by a washout technique, is higher in the distal than in the proximal smooth muscle segment. A difference in membrane permeability to rubidium and hence, potassium between proximal and distal smooth muscle segments may account in part for the different intracellular potassium concentrations.

Animals↗
PubMed1978

[Ultrasonic diagnostics in the scope of clarification and prognosis of oncologic cases (author's transl)].

By means of ultrasonic diagnosis it is possible to represent neoplasms in the abdomen, retroperitoneum and small pelvis. The real-time scanner is utilized in tumor localization and search for metastases, whereas an exact measurement of the tumor, possible of a representative metastasis, and also the treatment planning, are performed with the cross-sectional images from the storage compound scanner. Controls during cancer therapy will give information about the therapeutic results. Recurrences or newly spread metastases may easily be detected by this method in the course of follow-up of the tumor patients.

Abdominal Neoplasms↗
PubMed1978

[Sperm allergy of the anaphylactic type].

A case of an anaphylactic type of allergy is reported with pruritus, mucosal edema, asthma and shock symptoms which developed in a 26 year old female against her husbands sperma fluid. Symptoms and test results are compared with those of six other published cases. Results of skin tests obtained with a fraction of sperma plasma separated by chromatography are indicating that the antigen is of protein nature with a molecular weight of about 14.100. A molecular weight between 12.400 and 24.00 has also been reported in the literature.

Adult↗
PubMed1977

Intestinal tuberculosis: experience at a Canadian teaching institution.

Thirteen cases of inflammatory bowel disease suspected to be intestinal tuberculosis are analyzed. In nine, the diagnosis was established from such criteria as caseation necrosis, positive acid-fast stains or cultures of the diseased tissue. In four others, enteric tuberculosis remained a diagnostic possibility as judged by the following criteria: coexistence of the bowel lesion with established tuberculosis elsewhere, a clear response to antituberculous chemotherapy, or typical features on roentgenographic, surgical or histologic examination. The patients with intestinal tuberculosis were not necessarily recent immigrants or poor, nor did they have coexistent active pulmonary disease. Although most exhibited classic features of intestinal tuberculosis, the diagnosis was rarely considered at first. A greater awareness of the entity is needed to avoid confusion between intestinal tuberculosis and Crohn's disease.

Adult↗
PubMed1977

[The ultrasound appearances of thrombosis of the inferior vena cava due to renal tumours (author's transl)].

The findings of ultra-sound in four cases of thrombosis of the inferior vena cava due to malignant renal tumours are described. In three patients the cava was occluded by tumour, twice by infiltration and once by a mobile tumour mass in the vessel. The advantages of rapid imaging of normal and abnormal vascular structures are described. The method can demonstrate the occluding material in the vessel as well as showing the extent of local tumour infiltration around the cava, information which cannot be provided by cavography in the presence of complete occlusion.

Adenocarcinoma↗
PubMed1977

A potassium gradient in smooth muscle segment of the opossum esophagus.

Sodium and potassium content were determined in the smooth muscle segment of the opossum esophagus. Extracellular space measurements were also made using inulin and mannitol as markers. The muscle also made using inulin and mannitol as markers. The muscle was sampled at five sites spaced equally along the esophageal segment. On site in the stomach was also examined. The mean tissue sodium content was 36.6 +/- 10.7 meg/kg, and the mean tissue sodium content was 83.5 +/- 2.9 meg/kg wet wt. The mean inulin space was 184 +/- 34 ml/kg, and the mean mannitol space was 249 +/- 20 ml wet wt. The tissue potassium content was found to decline from 48.4 /- 10.1 meg/kg at the proximal site to 23.6 +/- 8.0 meg k/g at the distal site. The slope of electrolyte values from sites 1 through 5 was significant for both potassium and sodium. Extracellular space volume did not differ significantly from one end of the smooth muscle segment to the other.

Animals↗
PubMed1977

Esophageal manometry in the opossum.

The opossum esophagus is commonly used as an animal model of the human esophagus. We used esophageal manometry in normal animals to provide basal data about normal esophageal motor functions in vivo in this species. At rest, separate and distinct high pressure zones can be recorded at the level of the lower esophageal sphincter, diaphragmatic hiatus, aortic arch, and upper esophageal sphincter. Each zone demonstrates a characteristic pattern of pressures in the radii of the coronal section and a characteristic response to swallowing. The hiatal and aortic zones can be mistaken for the esophageal sphincters. Pressures in the sphincters fall with swallowing. Peristalsis is not bolus-dependent and occurs with 98% of swallows. Pressures generated by peristalsis are greater in the middle of the esophagus than at the ends. Values for resting lower esophageal sphincter pressure and the characteristics of peristalsis were reproducible between different studies in the same animals.

Animals↗
PubMed1977

Lower sphincter of the opossum esophagus in pseudopregnancy.

To seek a possible role of estrogen and progesterone in the development of changes in esophageal function during pregnancy, we produced a state of pseudopregnancy by administration of hormones to a suitable animal model. Twenty-two female opossums weighing an average of 2.5 kg, were divided into two groups. The treated group received intramuscular injections of 100 microgram of estradiol valerate daily from day 1 to day 12 and 15 mg of medroxyprogesterone acetate from day 7 to day 12. The control group received no injections. Both groups underwent manometry on days 1, 7, and 12. Lower esophageal sphincter pressure decreased (P less than 0.05) in treated animals from 58 +/- 13 mm Hg and 57 +/- 11 on days 1 and 7, respectively, to 44 +/- 10 mm Hg on day 12. The lower esophageal sphincter pressure remained unchanged in control animals. In both groups, there was no change in peristaltic wave pressure, duration, or velocity in the distal 6 cm of the esophagus. No abnormal peristaltic phenomena were observed. Esophageal muscle strips prepared from treated animals showed responses to electrical field stimulation of intrinsic nerves that were like those from control animals. The same was true for responses to acetylcholine and pentagastrin. Total tissue water and total tissue potassium content did not differ in treatment and control animals.

Acetylcholine↗
PubMed1977

[Ultrasonic examination of localized pancreatic lesions (author's transl)].

The technique of ultrasound examination of pancreatic lesions using real-time and compound scanning complementarily is described. Cases with localized lesions, e.g. pseudocysts, carcinoma, insulinoma and circumscribed inflammatory processes are demonstrated. A lesion not reflecting ultrasound in A and B mode is suggestive of a pseudocyst. Localized lesions reflecting ultrasonic waves cannot be differentiated; cytological or histological examinations have to be done in these cases.

Diagnosis, Differential↗