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Biomedical subjects

K Schulze

Publications and source records attributed to K Schulze.

136 records · Page 8Linked to original sources
PubMed1976

[Ultrasonic diagnosis in diseases of kidneys (author's transl)].

The diagnostic value of echoscopy and echography in kidney disease is presented and illustrated. Ultrasound examination is primarily used for the differentiation of cystic and solid lesions of the kidney. Our personal experience and the recent literature on this problem is reviewed. Based on the overall diagnostic accuracy of more than 90%, a procedure to investigate space occupying lesions of the kidney is suggested. The indication for ultrasound scans in obstructive kidney disease and the unilateral nonexcreting kidney is briefly discussed.

Abscess↗
PubMed1976

Echoscopic and echographic differential diagnosis of pancreatic lesions.

Combined echoscopic and echographic examination enables accurate display of the pancreatic region. Furthermore, this method yields reliable results in demonstrating pathological changes of the pancreas caused by acute pancreatitis, acute necrotising pancreatitis, pancreatic pseudocyst and neoplasm of the pancreas. The characteristic ultrasonographic findings in these diseases are presented and the differential diagnosis is briefly discussed.

Acute Disease↗
PubMedDate not supplied

Significance of the adenine nucleotide translocator in the pathogenesis of viral heart disease.

We found recently autoantibodies against the adenine nucleotide translocator (ANT), a carrier in the inner mitochondrial membrane, in sera of patients with myocarditis and dilated cardiomyopathy. To elucidate whether these antibodies are of pathophysiological importance, we investigated the function and expression of the adenine nucleotide translocator (ANT) in the heart muscle tissue of patients suffering from myocarditis and DCM. We found a markedly lowered transport capacity of the translocator accompanied by an elevation in total ANT protein content. The alteration in ANT protein amount is caused by an ANT isoform shift characterized by an increase in ANT 1 isoform protein associated with a decrease in ANT 2 isoform and an unchanged ANT 3 content. It could be shown that the isoform shift is not a progressive process during the disease period but an event in the early period of illness which becomes permanent. Simulating the effect of pathogenetic factors of autoimmunological diseases, we infected A/J mice with the enterovirus Coxsackie B3 and immunized guinea pigs with myocardial ANT protein. Both treatments led to autoimmunological responds and to a lowered myocardial transport capacity of ANT, to a disturbed energy metabolism and consequently to a depression of heart function.

Animals↗
PubMedDate not supplied

Eosinophilic gastroenteritis involving the ileocecal area.

Eosinophilic gastroenteritis, an idiopathic inflammation of the alimentary canal, is characterized by infiltration of the intestinal wall by eosinophils, massive submucosal edema, and peripheral eosinophilia. It is generally confined to the gastric antrum and proximal small intestine. A young woman had an eosinophilic infiltrate that involved the distal ileum and right colon only. Barium studies showed severe narrowing and shortening of the cecum and ascending colon. Symptoms of intestinal obstruction did not respond satisfactorily to conservative measures. Adhesions over the ileocecal area as well as thickening and induration of the terminal ileum and proximal right colon were found on hemicolectomy. The remaining intestine and the peritoneal cavity were felt to be normal. Histologic examination showed a cellular infiltrate with prominent eosinophils in the mucosa, submucosal edema and fibrosis. During a 40-month follow-up period after the hemicolectomy, the patient has not shown clear evidence of recurrence or extension of the disease to the stomach or proximal small intestine. It is concluded that idiopathic eosinophilic gastroenteritis may primarily involve the ileocecal area. In that location it must be specifically differentiated from intestinal tuberculosis, amebiasis, and Crohn's disease.

Adult↗