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Biomedical subjects

K Marek

Publications and source records attributed to K Marek.

At least 73 records · Page 4Linked to original sources
PubMed1982

[Evaluation of occupational exposure to cadmium on the basis of its concentration in the air and body fluids].

92 cadmium accumulators operators had their blood and urine cadmium concentrations determined. At nine workstations, during three years, repeated CdO concentrations measurements were made in the air by a stationary method, and additionally, at two workstations, measurements by an individual sampler were taken. The investigation showed a good correlation between CdO airborne concentrations measurements made by a stationary method and those made by individual samplers only at those workstations where workers do not change their place during a working day. Cadmiumuria indicated a greater dependence on the degree of exposure than did the concentration of this metal in blood. The findings suggest that cadmium concentration in blood and urine after body stores saturation is a better informant of current exposure than of cadmium stored in the organism.

Air Pollutants↗
PubMed1979

[Effect of metal dust on the respiratory system. I. Experimental studies].

The Wistar rats were intratracheally administered 50 mg of PbO dust, the same amounts of metalliferous dust from one of lead--and zinc works and of ferrotungsten dust, and 10--15 mg of cadmium dust (greater doses of cadmium dust resulted in animals' death). After 6 months, and in the case of cadmium dust after 9--12 months, the animals were dissected and their lungs were morphologically examined and hydroxyproline level was determined. In all groups hydroxyproline was found to be increased but fibrosis was different, especially in the group exposed to cadmium dust.

Animals↗
PubMed1979

[Effect of metal dust on the respiratory system. II. Clinical examinations].

Studies were carried out in 4 groups of workers occupationally exposed to cadmium, tungsten, manganese and lead. All those groups were homogeneous, composed exclusively of men aged 35--45, of similar height, body weight, and duration of employment above 10 years. Following the same criteria, a group of forestry workers, unexposed to dust, was randomly selected. The smoking habit was similar in all groups. Several--days--clinical observation included a detailed interview (MRC questionnaire), physical and radiological examination and a wide range of functional tests of lungs. The results reveal clinical and physiopathological symptoms which might be indicative of emphysema. The results of some studies also indicate the possibility of intraparenchymatous fibrosis of lungs in the tungsten--exposed--workers. No clear effects upon the respiratory system were found.

Adult↗
PubMed1979

[Radiological picture of pneumoconiosis in welders].

In the group of 35 welders with pneumoconiosis, the evolution of radiological changes was observed, after cessation of work in exposure. In 9 cases radiological changes retreated completely; in 16 cases they were clearly reduced, whereas in the remaining 10 persons no changes in radiological picture were found. The findings indicate that the radiological changes in welders' lungs may be reversible and as such they are most probably induced by dust retention.

Adult↗
PubMed1978

Ultrastructure of rat pinealocytes in vitro: influence of gonadotropic hormones and LH-RH.

The influence of gonadotropic hormones on the ultrastructure of rat pinealocytesin short-term organ culture was studied. Human chorionic gonadotropin (HCG), as well as pregnant mare serum gonadotropin (PMSG), caused a marked activation of pinealocytes. An hypothesis is discussed implying the presence of a feedback mechanism between the pineal organ and the hypothalamo-hypophysial system.

Animals↗
PubMed1978

Influence of gonadotropic hormones on the ultrastructure of rat pinealocytes.

The influence of gonadotropic hormones on the ultrastructure of rat pinealocytes was studied. Human chorionic gonadotropin (HCG) as well as pregnant mare serum gonadotropin (PMSG) caused a marked activation of pinealocytes. It is characterised by a conspicuous proliferation of the granular endoplasmic reticulum and Golgi apparatus as well as an increase in number of dense core vesicles, mitochondria, dense bodies, subsurface cisternae and vesicles in the terminal buds of pinealocyte processes. The changes after HCG administration were more pronounced than after PMSG.

Animals↗