Thyrotropin-releasing hormone--increased catabolism of catecholamines in brains of thyroidectomized rats.
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Biomedical subjects
Publications and source records attributed to K Marek.
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These examinations are based on an individual questionnaire and medicinal documentation of 8302 miners employed in 3-coal mines. In the previous parts an influence of occupational factors and socio-living conditions upon the occurrence of peptic ulcer in miners was presented. At present, on the ground of an analysis of 657 cases of peptic ulcer found among the examined population, considerable differences in the course of the disease in individual employed groups were found. In underground miners the cases with frequent recurrences were more frequent, compared with the staff employed on the surface. The amount of sick leaves caused by peptic ulcer was five times greater; the rate of absenteeism was the greatest. Recent cases (lasting no longer than 5 years), prevailed. Among the surface workers, as opposed to the under-round staff, almost all the cases of peptic ulcer called for hospital treatment. The percentage of chronic cases was much greater, the amount of complications and operations was twice as great. Sickness absenteeism caused both by peptic ulcer and other diseases was incresed. Hence it is evident that the work underground is too strenuous for those suffering from gastric ulcer and the miners with a heavy course of the disease most probably change the work i.e. they are transferred to the surface.
In 3-pit coal mines, all workers were examined by means of an inquiry. Apart from personal data the inquiry included information on the category of work performed, length of employment, family state and socio-living conditions as well as diseases of digestive tract. The diagnosis of peptic ulcer and data on its course were based on medical documentation of Plant Outpatient Departments. Collected material comprised 9361 persons, i.e. 95% of the whole population examined. After having excluded women, employed only on surface, results were worked out concerning the population of 8302 men employed both underground and on surface. In this mining population one found 7.92% persons suffering from peptic ulcer; thus the occurrence of the disease resembled that of general population. The rate of duodenal and gastric ulcer was identical. The studies indicated that the percentage of peptic ulcer was increased proportionally to age and number of children and was greater in married than in bachelors. No greater percentage was found in widowers and divorcees, or in those eating in canteens, partaking cold meals during work or drinking alcohol. Instead in smokers a greater percentage of peptic ulcer was found. The rate of the occurrence of peptic ulcer is greater with higher salaries, additional paid, or social, work, and in case of daily travelling on a motorcycle or bicycle. Finally it was indicated that those suffering from peptic ulcer limited smoking and drinking habits and endeavoured to be fed properly.
In the part I the effect of social and life factors on the development of peptic ulcer in miners has been analysed. Now, in the same population of 8302 miners composing the crew of three coal mines, an evaluation of the role of occupational factors has been performed on the basis of inquiry and documentation data of the outpatient department. It was found that the frequency of peptic ulcer is more dependent on years of employment than on age. The percentage of peptic ulcer cases among the underground crew and this working on the surface did not reveal distinct differences. Only in miners, working underground a shortest time, it was less than in the analogous groups working on the surface. Among miners performing the longest time very arduous work, the frequency of peptic ulcer is less than in the remaining crew. The psychical burden and the paid by the job system as well as night shift work influence the increase of patients. These results demonstrate that in the mining the peptic ulcer hazard is augmented by similar factors as in other industries, the effect of underground work however has not been observed. The conditions of mining induce miners suffering from peptic ulcer to avoid more burdening job and this is why percentage of ill miners is less among those whose work is more arduous.
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As key stakeholders from the clinical setting and vendor communities, the authors share a summary of their collective experience related to the challenges and issues associated with implementing the vocabularies recognized by the American Nurses Association in several installations of commercially available clinical information systems. Although the focus of the article is on summarizing the challenges and issues, it is of note that the authors' experiences across care settings suggest that the experience and effort of using one of the ANA-recognized vocabularies in a computer-based system are essentially worthwhile and positive. The issues and challenges fall into two categories: 1) those related to the developmental status of nursing vocabularies, and 2) those related to the adoption or implementation of new technology.
The aim of the present study was to investigate the ultrastructure of pinealocytes and plasma melatonin concentrations in Fischer rats bearing an advanced (14th) passage 7,12-dimethylbenz[a]anthracene-induced mammary tumor. Quantitative ultrastructural analysis of the cell size and relative volumes of various cell organelles as well as the number of dense-core vesicles was performed in pinealocytes of the animals killed either during the daytime (15.00 h) or at night (3.00 h) 1 month after tumor transplantation. No significant differences between control and tumor-bearing animals were observed either during the daytime or at night. However, plasma melatonin concentrations in tumor-bearing rats killed at 3.00 h were suppressed by 35% (p < 0.025) when compared to the control animals killed at the same time.