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Biomedical subjects

K Hamano

Publications and source records attributed to K Hamano.

At least 253 records · Page 14Linked to original sources
PubMed1989

[Intrascrotal sclerosing lipogranuloma: a case report].

We report a case of genital sclerosing lipogranuloma, which lacks any causative agents or episode of genital trauma. The patient was a single male of 27 years old. Open biopsy revealed it lipogranuloma with no evidence of malignancy. Cut surface of the removed mass was solid and greyish white. The histopathological diagnosis was sclerosing lipogranuloma. The remnant of the mass disappeared after the treatment with an anti-inflammatory agent. No recurrence has occurred for 1 year and 10 months.

Adult↗
PubMed1989

[Changes in postoperative colloid oncotic pressures after open heart surgery especially in relation to recovery of the hemodynamic and respiratory status].

In order to evaluate the relationship among the changes of colloid oncotic pressure (COP), hemodynamic and respiratory recovery after open heart surgery, cardiac index (CI), pulmonary capillary wedge pressure (PCWP), (A-a)DO2, urine output and COP were measured in 33 patients during 48 hours after the cardio-pulmonary bypass (CPB). The patients were divided into three groups according to COP values at 3 and 24 hours after CPB. Twenty three patients whose COP values were normal (COP greater than or equal to 19 mmHg) at 3 hours after CPB maintained stable hemodynamic and respiratory status. Cardio-respiratory status were deteriorated in the 6 patients whose COP values were below normal both 3 and 24 hours after CPB. On the other hand, 4 patients with normal (A-a)DO2 and low COP values at 3 hours after CPB demonstrated rapid recovery of COP values and improvement of cardiac function. It is concluded that the patients with both cardiac and respiratory dysfunction have low COP values during 48 hours after CPB, but the patients with normal (A-a)DO2 and low COP at 3 hours after CPB demonstrate the recovery of COP values with rapid improvement of cardiac function until 24 hours after open heart surgery.

Cardiopulmonary Bypass↗
PubMed1989

[A case of bronchobronchiolitis obliterans with Castleman's lymphoma].

The aim of this paper is to report a very rare case of bronchobronchiolitis obliterans accompanied by mesenteric Castleman's lymphoma. A 45-year-old woman was admitted to our hospital with progressive exertional dyspnea. Chest radiography showed overinflated lungs suggesting emphysema and pulmonary function tests revealed severely restrictive as well as obstructive impairments. Selective alveolobronchogram and endoscopy using a thin fiberoptic bronchoscope (3 mm in diameter) demonstrated multiple obstructions of small bronchi. Using a biopsy forceps, a small piece of tissue of bronchial wall was obtained from the focus of obstructive change, which showed histologically nonspecific inflammatory change including granulation. Therefore, we diagnosed her disease as bronchobronchiolitis obliterans (BBO). In addition, she had a large abdominal mass. On operation, it was found to be located in the mesenterium. It was then removed and the histological examination revealed Castleman's lymphoma, hyaline-vascular type. After operation, the blood IgM level, which was high on admission decreased rapidly and her dyspnea was reduced, suggesting that Castleman's lymphoma was related to the pathogenesis of her respiratory disease.

Bronchiolitis Obliterans↗
PubMed1989

[Surgical considerations after patch closure of atrial septal defect with tricuspid annuloplasty].

Two patients with complications of embolism during the early postoperative period after patch closure of atrial septal defect with tricuspid annuloplasty were reported. Case 1: A 58-year-old woman underwent closure of an atrial septal defect and tricuspid annuloplasty by means of Kay's technique for tricuspid regurgitation. She had an episode of thromboembolism in the bilateral common femoral arteries 7 days after surgery. Thromboembolectomy was performed successfully using Fogarty's embolectomy catheter. Case 2: A 49-year-old woman underwent closure of an atrial septal defect and the tricuspid annuloplasty using Carpentier ring for tricuspid regurgitation. The patient had transient left hemiparesis on the 5th postoperative day. Both patients had atrial fibrillation and mild pulmonary hypertension before surgery. In relatively old patients (over 40 years old) with atrial septal defect, tricuspid regurgitation and atrial fibrillation, anticoagulant therapy should be started immediately after surgery to prevent thromboembolism.

Female↗
PubMed1989

[Secondary amyloidosis of the bladder associated with Sjögren's syndrome: a case report].

A 57-year-old woman visited the Mie University Hospital with the complaint of lower abdominal pain on December 2, 1987. Cystoscopic examination revealed a non-papillary tumor with a broad base in the left posterior wall. A diagnosis was made by biopsy of the bladder epithelium. Amyloid fibrils were confirmed in the biopsy specimen with polarization and electron microscopies. Symptomatic secondary amyloidosis of the bladder is very rare. To date, only 15 cases have been reported in the American and European literatures. This seems to be the first case reported in Japan.

Amyloidosis↗
PubMed1988

Marked cerebrospinal fluid collection associated with hepatic failure.

We report two cases with abnormal CSF accumulation in the cranium. One case had marked dilatation of the ventricular system, for which a ventriculoperitoneal shunt was carried out. The shunt was not beneficial and it turned out that the patient was suffering from ornithine transcarbamylase deficiency. The second case developed marked subdural effusion after fulminating hepatic failure and septicemia, for which drainage of the subdural space and subsequent insertion of Ommaya reservoirs were carried out. In spite of successful CSF control, the outcome was bad, both cases being incapacitated due to severe encephalopathy probably caused by hyperammonemia. The results of serial computed tomographic follow-up are presented.

Acute Kidney Injury↗
PubMed1987

Seasonal changes in inhibin activity in seminal plasma and serum concentrations of FSH, LH and testosterone in the male goat (Capra hircus).

Inhibin activity in goat seminal plasma was measured by in vitro assay throughout successive 9 months and its relationship with the serum FSH, LH and testosterone concentrations was investigated. Total inhibin activity (TIA) in seminal plasma gradually increased from spring to summer, reduced in autumn (P<0.05) and recovered toward winter (P<0.05). Serum FSH and LH reached a peak in mid-summer (P<0.01) and returned to the low levels in autumn. Serum testosterone also increased in mid-summer and kept the high levels until the early winter (P<0.05). Some positive correlation was found in monthly levels between seminal TIA and serum FSH (r=0.305; P<0.05). Results suggest that the summer increase of inhibin activity in seminal plasma relates with the mid-summer rise of serum FSH levels in the male goat.

Journal Article↗
PubMed1986

Muscle involvement in a case of oculocutaneous albinism.

A 2-month-old girl with tyrosinase-positive oculocutaneous albinism (OCA) and severe muscle hypotonia is reported. She was admitted to our hospital because of poor sucking and poor weight gain. On physical examination she was found to have generalized muscle weakness and multiple anomalies including deafness, mental retardation, cataracta and a high-arched palate. A muscle biopsy showed marked variation in fiber size with bimodal distribution, suggesting a neuropathic process. Since electromyography showed a myopathic pattern, CK was definitely elevated and muscle histologic examination did not show any denervation of the type found in Werdnig-Hoffmann disease, the present disorder was assumed to be caused either by hardly developed motoneurons or by abnormal interaction between muscles and nerves.

Adenosine Triphosphatases↗
PubMed1986

Focal perivascular alterations of white matter in herpes simplex encephalitis--a histological and immunocytochemical study.

Several cases of human herpes simplex encephalitis treated with Vidarabin have been investigated with the histological and immunocytochemical techniques. Cases with a subacute evolution revealed areas of focal perivascular myelin destruction in the white matter. The distribution of herpes simplex antigen did not show any preferential localization of the virus in perivascular oligoglial cells. In contrast, a spatial and temporal relationship has been found between the appearance of immunoglobulin-bearing cells around the vessels and that of areas of focal perivascular myelin damage. Therefore, it is postulated that the areas of focal destruction of myelin are not related to the cytotoxic effect of the virus but are rather dependent on the immune response of the host.

Adult↗
PubMed1986

[Intraarterial bolus infusion followed by rapid removal of anticancer agents with hemocarboperfusion under local hyperthermia in advanced hepatic cancer].

Reported herein is a new multidisciplinary treatment modality for unresectable hepatic cancer in which local hyperthermia and intraarterial infusion of bolus anticancer agent are simultaneously undertaken while anticancer agent leaking from the hepatic bed into the general circulation is rapidly removed by charcoal hemoperfusion. Local hyperthermia induced by exposure to 13.56-MHz radiofrequency waves was conducted between one and one and a half hours once or twice a week. During the hyperthermia treatment, a bolus of either 1 mg/kg Mitomycin C or 2 mg/kg Adriamycin was injected into the hepatic artery via a Vascular Access Port, the catheter portion of which had been surgically inserted into the hepatic artery and the reservoir of which had been implanted subcutaneously. In general, a regular dose of 6 mg of Mitomycin C was injected into the Vascular Access Port during the following hyperthermia procedures. In seven of nine patients (78%) treated with this method, a marked reduction in tumor size of more than 50% was observed on computed tomograms. A light to moderate degree of side effects such as leukocytopenia, thrombocytopenia, liver dysfunction or hair loss were noticed after the bolus infusion, but were not so serious as to threaten the patients' lives.

Adult↗