Search PubMed⌕ Search

Biomedical subjects

J Varga

Publications and source records attributed to J Varga.

At least 289 records · Page 16Linked to original sources

Effects of dopamine on renal functions in premature neonates with respiratory distress syndrome.

The renal effects of dopamine have been studied in preterm infants with RDS. Dopamine has been given in doses of 0.5-2.0 microgram/kg/min as a continuous intravenous infusion in cases of peripheral circulatory disturbances. As a result, the circulation became stable and some renal parameters improved. There was a + 106% increase of urine output as well as a + 73%, + 140%, + 21% increase in Na-excretion, FeNa, creatinine clearance respectively. In accordance with the marked increase in phosphorus excretion the titratable acidity was also increased. There was a significant decrease in the renal urea excretion and free water clearance. These alterations were probably caused by an intrarenal hemodynamic redistribution. The possible mechanism of the renal changes are also discussed. The observations demonstrate the functional maturity of renal dopaminergic receptors in the preterm infants.

Dopamine↗

[Preclinical and manifest hypothyroidism following thyroid gland operation].

62 patients who were strumectomized on account of carcinoma of the thyroid gland, hyperthyroidism and thyroiditis underwent an after-examination on an average 6 years after operation. In preclinical hypothyroidism which cannot be differed from euthyroidism on the basis of the thyroid hormone concentrations, or only by means of the TRH-tolerance test, an increased TSH-response after TRH-tolerance and a T3-preference in comparison to T4 were observed. In manifest hypothyroidism the compensatory mechanisms exhausted and despite the increased TSH-concentration in the serum the ability for TRH-stimulation and the concentrations of the thyroid hormone are reduced. In preclinical and manifest hypothyroidism are recommended ca. 160-170 micrograms thyroxin per day for the substitution therapy after operation of benign diseases of the thyroid gland and after operations of the thyroid tumour the suppression therapy with ca. 220 micrograms thyroxin per day.

Adult↗

Serotonin-immunoreactive cells in the superior cervical ganglion of the rat. Evidence for the existence of separate serotonin- and catecholamine-containing small ganglionic cells.

Superior cervical ganglia of 8 adult male rats were examined by indirect immunofluorescence microscopy, using an antibody to a conjugate of bovine serum albumin and serotonin, and an antibody to a conjugate of bovine serum albumin and noradrenaline. The fixative used was 4% paraformaldehyde in 0.1 M phosphate buffer, pH 7.3. Consecutive cryostat sections of whole ganglia were alternately stained with these antibodies. Serotonin- as well as catecholamine-immunoreactive, small ganglionic cells were demonstrated, both arranged in clusters. Serotonin-immunoreactive cells were mostly located at the cranial or caudal side of the ganglia. Serotonin-immunoreactive cells provided with processes were easily observed. Only a few mast cells were seen. Catecholamine-immunoreactive cells were rounded without processes. This cell type did not seem to have a preferential position within the ganglia. Intermingling of both immunoreactive, small ganglionic cells was not observed. A considerable variety in the number of both immunoreactive cell types was established. Catecholamine-immunoreactive cells were absent in 3 our of 8 animals. Evidence is provided that the catecholamine-immunoreactive cells are storing noradrenaline. The presented data seem to indicate the presence of 3 different types of small, intensely fluorescent (SIF) cells in the superior cervical ganglion of the rat, viz. a dopamine-storing, a noradrenaline-storing, and a serotonin-storing SIF cell type.

Animals↗

[Sodium, potassium and acid-base values of mother and newborn, following delivery by caesarean section under sombrevin (propanidid) anaesthesia (author's transl)].

Acid-base and electrolyte values of 24 newborns delivered by caesarean section are reported in this paper. Anaesthesia had been introduced by sombrevin-succinylcholine. No metabolic acidosis, which might have been attributable to sombrevin action, was recordable from any of the newborns. Acid-base values were normal, and somewhat increased potassium values returned to normal, soon.

Acid-Base Equilibrium↗

[Combined electro-anaesthesia for Caesarean section and gynaecological operations (author's transl)].

Reported in this paper are 98 cases of electro-analgesia in combination with endotracheal nitrous-oxide anaesthesia. A comparison has been made with 65 controls. Excessively stressing anaesthetics may be avoided in such combined electro-anaesthesia. No significant differences were found to exist between the above and conventional approaches, in the context of blood pressure, pulse, and interior temperature. Combined electro-anaesthesia, therefore, is recommended by the authors as a non-invasive method with good applicability to obstetrics and gynaecology.

Anesthesia, Endotracheal↗