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Biomedical subjects

J Ott

Publications and source records attributed to J Ott.

At least 235 records · Page 13Linked to original sources

[Psychotherapy for suicidal inclinations].

Suicidality is not an expression of a unique disease, but often the symptom of a neurotic reaction or of primary psychic maldevelopment. Forms of neurosis, where the number of symptoms is relatively small, tend to develop what may be called the "suicidality" symptom. Selection of the method of therapy depends, not upon the degree and seriousness of the inclination of commit suicide, but upon the underlying disease. In the case of neurotic reactions it is recommended to resort to the method of discussing the respective conflicts and make use of autogenic training. In the case of primary psychic maldevelopments it is necessary to choose a form of therapy centering on the personality, and this can be in the form of short-term specific therapy or in the form of group psychotherapy.

Humans↗

Estimating distances from the centromere by means of benign ovarian teratomas in man.

Under the assumption that benign ovarian teratomas in man arise parthenogenically from a germ cell by suppression of the second meiotic division, the distance of a gene from its centromere can be estimated from the observed proportion of heterozygous teratomas collected from heterozygous hosts. The frequency of heterozygous teratomas of heterozygous hosts is equivalent to the frequency of second division segregation at the gene locus which has been used for centromere-related mapping in fungal genetics for more than 40 years. Mapping functions useful for teratoma-based mapping in man are presented.

Chromosome Mapping↗

Human centromere mapping using teratoma data.

Under the assumption that benign ovarian teratomas arise parthenogenetically from a germ cell by suppression of the second meiotic division, the proportion gamma of heteratomas collected from heterozygous hosts is a measure for the distance between the corresponding gene and its centromere. For proportions gamma less than or equal to 0.3, the mapping function x = gamma/2 applies, where x is the map distance in Morgans.

Cells, Cultured↗

Linkage investigation of a large family with Reifenstein's syndrome.

Linkage analysis of a 116-member family with 11 males affected by Reifenstein's syndrome is reported. One X-chromosomal and eight autosomal markers were used. Close linkage can be excluded for P, K, MNS and Xg-a. A possibility of close linkage to ABO is discussed.

Disorders of Sex Development↗

[Objectification of psychopathological symptoms in patients with a depressive syndrome].

75 patients, classified as suffering from endogenous depression according to the Kielholz criteria, underwent a 6 week therapy with opium tincture. Following the phenomenological picture, two sub-divisions of syndromes were formed:--inhibited-depressive and uninhibited-depressive. These we have compared with each other according to their response to therapy. The depressive symptomatics were objectified in experimental psychology by means of the Beck scale. In the light of the Beck form of enquiry a significantly better response appears in the uninhibited-depressive patients under the influence of opium. Moreover a varying responsiveness of the separate depressive symptoms can be seen in the syndromic sub-divisions. Altogether it can be stated that the Beck scale for recording depressive syndromatics surpasses the general clinical assertion in both objectivity and reliability and has proved itself in the supervision of therapy.

Adult↗