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PubMed · 799523

Human centromere mapping using teratoma data.

J Ott·F Hecht·D Linder·E W Lovrien·B K McCaw
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Abstract

Under the assumption that benign ovarian teratomas arise parthenogenetically from a germ cell by suppression of the second meiotic division, the proportion gamma of heteratomas collected from heterozygous hosts is a measure for the distance between the corresponding gene and its centromere. For proportions gamma less than or equal to 0.3, the mapping function x = gamma/2 applies, where x is the map distance in Morgans.

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Cells, CulturedChromosome MappingFemaleGenetic TechniquesHumansMathematicsOvarian NeoplasmsTeratomaJournal ArticleResearch Support, U.S. Gov't, P.H.S.

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J Ott, F Hecht, D Linder, E W Lovrien, B K McCaw. 1976. Human centromere mapping using teratoma data.. https://doi.org/10.1159/000130641

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