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Biomedical subjects

J Moodley

Publications and source records attributed to J Moodley.

At least 271 records · Page 15Linked to original sources
PubMed1985

The incidence of major abdominal surgery after septic abortion--an indicator of complications due to illegal abortion.

That there is a high morbidity associated with illegal abortion is well known, but its exact extent is difficult to assess, since detailed statistics are not available and the nature of the morbidity is diffuse. We have assumed that abortal sepsis is a consequence of illegal interference with pregnancy. The incidence of major abdominal surgery after a septic abortion is used as an indicator of serious complications. This incidence is compared with that following legal abortion.

Abortion, Illegal↗
PubMed1985

Temporary blindness and eclampsia. A report of 2 cases.

Temporary blindness in 2 patients with eclampsia was associated with oedema of the occipital lobe of the brain. In addition 1 patient had retinal detachment. Management included the use of mannitol, dexamethasone and furosemide to reduce cerebral oedema. Both patients recovered their vision within 48 hours of this management.

Adult↗
PubMed1985

Syphilis in pregnant black women.

Serological tests for syphilis (with rapid plasma reagin) were performed in 2 767 women attending the antenatal clinic of King Edward VIII Hospital, Durban, for their first, booking visit. The test was repeated at the 36th week of pregnancy. A total of 152 women (5,5%) were assumed to have syphilis. In addition, 4 (11,8%) of 34 patients who were seronegative at less than 32 weeks of pregnancy had a positive serological test result at 36 weeks.

Black or African American↗
PubMed1985

Malaria in pregnancy.

Malaria is a potentially lethal disease. In pregnancy its deleterious effects are aggravated by the depressed immune state. Every pregnant patient presenting with pyrexia of unknown origin should be screened for malarial parasites, especially if she has travelled to or come from an area in which malaria is endemic. Case histories of 2 pregnant women with malaria are presented and the diagnosis, treatment and chemoprophylaxis thereof are discussed.

Adult↗
PubMed1985

Rupture of the gravid uterus.

A detailed analysis of 129 cases of rupture of the gravid uterus between 1980 and 1983 is presented and compared with two previous reports from King Edward VIII Hospital, Durban, over the last 2 decades. Statistically significant decrease in the occurrence of this condition (from 2,7 to 1,06/1000 deliveries (P less than 0,001; chi 2 = 20,38)) and in the maternal mortality rate (from 12% to 3%) have taken place since the initial study. The most probable reasons for this improvement are the provision of a community-based obstetric service, the early detection of cephalopelvic disproportion, awareness of the condition, immediate and adequate resuscitation once the diagnosis is established, and the performance of a total abdominal hysterectomy as definitive treatment in most cases.

Adult↗
PubMed1985

The HELLP (haemolysis, elevated liver enzymes, low platelet count) syndrome in severe hypertensive crises of pregnancy--does it exist?

The HELLP syndrome, comprising haemolysis, elevated liver enzyme values and a low platelet count, was studied in 26 women with hypertensive crises of pregnancy and in matched controls. Platelet counts and bilirubin, lactate dehydrogenase, aspartate transaminase and haematocrit levels together with peripheral blood smears were studied on the day of admission and on the 7th day after delivery. Only 1 woman with pre-eclampsia was found to have had the HELLP syndrome; the case report is presented and the laboratory investigations are discussed.

Adolescent↗
PubMed1985

Cardiopulmonary arrest after the administration of magnesium sulphate. A case report.

The death of a patient from cardiopulmonary arrest after the administration of magnesium sulphate for imminent eclampsia is reported. It has long been recognized that magnesium sulphate provides rapid control of convulsions in eclamptic patients with minimal sedative effects on both mother and fetus. However, because of the neuromuscular blocking action of magnesium and the narrow margin between therapeutic and toxic serum levels, the drug must be given with caution. A regimen for magnesium sulphate administration is advocated which allows safe and effective control of convulsions in eclampsia.

Eclampsia↗
PubMed1985

Peritoneal tuberculosis imitating ovarian carcinoma "special category".

A case report, of a patient with peritoneal tuberculosis in whom the provisional diagnosis of ovarian carcinoma--"special category" was made is presented. As most gynecologists see hardly any cases of peritoneal tuberculosis nowadays, this possible diagnosis--which should always be considered--is reviewed. It illustrates the importance of a definite histopathological diagnosis.

Adult↗
PubMed1985

Intravenous glucose tolerance tests in women with twin pregnancy.

Carbohydrate metabolism was evaluated in 20 twin gestations and 20 singleton pregnancies. The groups were matched for age, parity, weight, height, and gestational age. Intravenous glucose tolerance tests were performed on all women in the third trimester of pregnancy using a glucose load of 0.5 g/kg body weight. Venous plasma glucose and insulin level were measured and statistically compared. The glucose disappearance rates (K) were not different in the two groups. No significant differences in the mean insulin or glucose responses were found between singleton and twin pregnancies. Thus, twin gestations are not at higher metabolic risk of gestational diabetes than are singleton pregnancies.

Adult↗
PubMed1984

Central venous concentrations of immunoreactive prostaglandins E, F, and 6-keto-prostaglandin F1 in eclampsia.

Concentrations of prostaglandins E, F, and 6-keto-prostaglandin F1 alpha were estimated in central venous blood and amniotic fluid in 21 women with eclampsia and 16 healthy pregnant controls. Central venous blood concentrations of 6-keto-prostaglandin F1 alpha and prostaglandin E were significantly lower in patients than controls before delivery and remained reduced for at least 48 hours after delivery. Low concentrations of prostaglandins E and 6-keto-prostaglandin F1 alpha are probably directly related to the pathogenesis of eclampsia.

6-Ketoprostaglandin F1 alpha↗
PubMed1984

Measurement of phosphatidyl glycerol in amniotic fluid. Results in clinical practice.

A relatively rapid, unidimensional method of measuring phosphatidyl glycerol (PG) in amniotic fluid in order to assess pulmonary maturity was compared with measurement of the lecithin/sphingomyelin (L/S) ratio and the bubble test. Measurement of PG alone gave a higher predictive value (95%) than the L/S ratio while maintaining a low ratio rate of false-positive (2,3%) and false-negative results (3,1%).

Adolescent↗
PubMed1984

Reversible tubular lesion in pregnancy-induced hypertension detected by urinary beta 2-microglobulin.

Serum and urine beta 2-microglobulin concentrations were measured in 17 primigravidas with mild pregnancy-induced hypertension and nine normotensive control patients matched for gestational age. Serum beta 2-microglobulin and creatinine clearance values were not different between the two groups but urinary excretion of beta 2-microglobulin was three times higher in the hypertensive patients. This difference disappeared within seven days of delivery. These results indicate that a reversible renal tubular lesion occurs in pregnancy-induced hypertension even in the absence of detectable proteinuria.

Birth Weight↗
PubMed1984

Amniotic fluid prostanoids in preeclampsia.

Amniotic fluid from 19 patients with preeclampsia was compared with samples from normotensive control subjects with respect to the levels of prostaglandin 6-keto prostaglandin F1 alpha, thromboxane B2, and the ratio of 6-keto prostaglandin F1 alpha to thromboxane B2. The study found no significant differences in the levels of these prostanoids or the ratio of 6-keto prostaglandin F1 alpha to thromboxane B2 (study patients, 2.7 +/- 2.1; control patients, 2.8 +/- 1.9) between groups.

6-Ketoprostaglandin F1 alpha↗
PubMed1983

Maternal glycosylated haemoglobin values after delivery of large infants and unexplained stillbirths.

Glycosylated haemoglobin (Hb A1) values were estimated immediately after delivery in 29 patients who had given birth to a large infant, in 25 who had delivered a macerated stillborn infant, and in 31 controls matched for age and parity. No difference in mean Hb A1 values was found between mothers of normal-sized and of large infants. The mean Hb A1 level for the mothers who had delivered a macerated stillborn infant was higher than that for the control group (8,26% v. 7,65%). Although this was not statistically significant, there were 5 patients with a raised Hb A1 value and a normal glucose tolerance test result; this may suggest gestational diabetes.

Adult↗
PubMed1983

Carbohydrate metabolism in twin pregnancy.

Carbohydrate metabolism was evaluated in 26 women with a twin pregnancy and 26 women with a singleton pregnancy. The groups were similar in respect of age, parity and gestational age. Each woman had an oral glucose tolerance test. No significant differences in venous blood sugar values or insulin responses were found between singleton and twin pregnancies.

Adult↗