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Biomedical subjects

J Lecomte

Publications and source records attributed to J Lecomte.

At least 199 records · Page 11Linked to original sources
PubMed1980

[Anaphylactic shock in brown Norway rats with reagins and no precipitins in the blood (author's transl)].

Brown Norway rats have been actively sensitized against hen ovalbumine mixed with anti Bordella pertussis vaccine. After ten to twelve days, IgE are detected in the blood, but no precipitins. Anaphylactic shock induced by i.v. injection of 1 mg.100 g-1 body weight of ovalbumine is caracterized by a vascular collapse, the animal dying in about 15 minutes. This collapse is identical with the same general anaphylactic reaction as observed in the Wistar rats, which have large amounts of precipitins in the blood.

Anaphylaxis↗
PubMed1980

[Antigenic characterization of influenza A virus isolated from birds captured in Ontario, Quebec, and the maritime provinces during the 1977 season].

A total of 145 influenza A viruses were isolated from ducks, geese and passerine birds in Ontario, Québec and the Maritimes in July-August 1977. Antigenic characterization of these isolates included five hemagglutinin (Hsw1, Hav4, Hav5, Hav6, Hav7) and five neuraminidase subtypes (N1, N2, Neq1, Neq2, Nav1) in nine different combinations; one combination Hav7 Neq1 had not been previously reported. The majority of these viruses were Hsw1 N1, antigenically related to influenza viruses in pigs and humans. This large reservoir of influenza A viruses circulating in ducks may well be involved in the appearance of new viruses in other species, including humans.

Animal Population Groups↗
PubMed1979

Influenza viruses in birds: rapid identification by counterimmunoelectrophoresis.

Counterimmunoelectrophoresis with an antiserum raised in rabbits against the M protein of the avian N virus proved to be particularly useful for large-scale identification of influenza A virus isolates. Of a total of 231 hemagglutinating agents isolated from 1,656 rectal swabs collected from shore and open-country birds, 158 could be identified as influenza A viruses by counterimmunoelectrophoresis, and 75 were serologically related to Newcastle disease virus by hemagglutination inhibition with an antiserum to Newcastle disease virus. Two isolates contained a mixture of influenza A virus and Newcastle disease virus; although the Newcastle disease virus virus particles outnumbered the influenza A virus particles in a ratio of 1,000:1, as seen by electron microscopy, the latter could be readily detected by counterimmunoelectrophoresis. This type of assay appears to be of potential use for epidemiological surveillance of influenza virus isolated from humans and animals. It combines specificity, sensitivity, and simplicity.

Animals↗
PubMed1979

[Effect of pindolol on tachycardia and certain metabolic variations dependent of muscular exertion].

1. -- In young well trained adults, adrenergic beta receptors blockade by pindolol or propranolol causes a relative bradycardia during running on a threadmill during 10 to 20 min at 50% VO2 max. 2. -- Pindolol activity is maximum for 5-7.5 mg ingested one hour before starting. In two subjects, tachycardia reappears for 30 mg : this secondary increase may be explained by an intrinsic sympathetic activity of pindolol. 3. -- Propranolol is about 14 times less active than pindolol without any intrinsic sympathetic activity.

Adult↗