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Biomedical subjects

J Kermarec

Publications and source records attributed to J Kermarec.

At least 55 records · Page 3Linked to original sources
PubMed1980

[Pericardiac tamponade revealing a lympho-epithelial thymoma (author's transl)].

An inaugural pericardiac tamponade performed on a 39 years old man, reveals a lympho-epithelial thymoma. The anatomic diagnosis first suggested by the radiography after evacuation of the effusion, is confirmed by the swab taken during the retroxiphoidal drainage. A 57 Gray cobaltotherapy was then performed. 18 months later, a satisfactory general state, allowed the patient to return to his professional activity. The evaluation of a tumourous residue by a tomodensitometry, is discussed at the light of a comparable observation confirming the efficiency of cobaltotherapy but, at the same time, its agressivity for such an important target volume. A previous surgical reduction, whenever possible, is then considered; an unthinkable eventuality in the reported observation.

Adult↗
PubMed1979

[Effect of transfer factor on the immunity state of patients with bronchopulmonary cancer. A report on 12 cases (author's transl)].

The dialysate of an extract of leucocytes having transfer factor (TF) activity was administered, at a daily dose of 1 mg/ml of orcinol-sulphuric positive material, by intramuscular injection to 12 patients with bronchopulmonary cancer for 6 days. An increase in the percentage of E-rosettes and the absolute number of T lymphocytes was observed in 7 cases out of 10. Rapid healing of a widespread intercurrent zona and a regin of B.C.G. scarification reaction was also noted. The TF was well tolerated in most cases.

Adult↗
PubMed1979

[Histopathology of the liver in shock].

Microscopic lesions in shock liver, examined in biopsy specimens from 20 patients, are characterised by elective involvement of the hepatic parenchyma inthe peripheral zones of the acini, with necrosis and cell loss in approximately half the cases. The particular appearance of the degenerative lesions of the hepatocytes ("ischaemic atrophy" and tumefaction, monocellular necrosis), the absence of any change in the reticulin fibres, the minimal leucocytic reaction and the absence of any damage to the portal spaces should make it possible to identify histologically the ischaemic aetiology of peri-acinar hepatic lesions.

Humans↗
PubMed1979

[Characteristics and complications of mediastinal brochogenic cysts. A report on five cases (author's transl)].

Five observations of mediastinal brochogenic cysts are used to illustrate the diagnostic and/or therapeutic difficulties encountered in cases with an ectopic topography or complications. In two cases, one of which was clearly located in the posterior mediastinum and associated with a false erosive appearance of the nearby vertebral body, it was possible to establish the degree of ectopic displacement of the bronchogenic cysts, and to comprehend the pre-operative diagnostic difficulties and nosological problems associated with these sequestrations. As far as complications are concerned, one observation was able to confirm that a sudden volume increase doesn't always correspond to a septic process, and that rapid secondary reduction in volume is not always accompanied by fistulation. Intracystic suppurations differ in appearance according to their location. In the subcarinal region they can cause a fistula, as in the case reported. In other regions, in this case the left lateral tracheal area, suppuration is enclosed, but it can be associated with suppurative lesions of the adjacent lung. The operative difficulties, partial cystectomy in one case and associated lobectomy in the other, are further evidence for the need for systematic excision of all bronchogenic cysts as soon as they are diagnosed and before complications occur.

Adult↗
PubMed1978

[Allergic granulomatous angitis. A report on 4 cases (author's transl)].

The authors describe four new cases of allergic granulomatous angiitis presenting symptoms of bronchopneumonia with asthma, weight loss, and persistent fever. There was associated eosinophilia in each case, and the outcome was rapidly fatal. Autopsy confirmed the presence of characteristic lesions; necrotizing angitis, vein involvement, and extra-vascular granulomatous infiltration, mainly in the lungs and heart. The characteristic clinical, biological, and histological changes seen in Churg and Strauss's syndrome should enable differentiation from other granulomatous angititis affections, especially PAN. A different diagnostic approach is needed, however, as surgical biopsy of the lungs, and/or needle biopsy of the liver is necessary.

Adult↗
PubMed1977

[Angio-immunoblastic lymphadenopathy with dysproteinemia. Apropos of 5 cases].

Angio-immunoblastic lymphadenopathies with dysproteinemia represent a new entity characterised clinically by superficial lymphadenopathy splenomegaly more frequent than hepatomegaly, marked general signs and skin manifestations often triggered off by drugs. The laboratory disturbances include immue disorders, polyclonal dysproteinemia, anti-red cell autoimmunity. It is above all the histology which makes this entity original: polymorphic cellular proliferation with immunoblasts, plasmablasts and plasma cell disturbing the normal lymph node architecutre, intense vascular neogenesis and deposits of extra-cellular amorphous substances. This histology corresponds to a non-sarcomatous lymph node hyperplasia, probably due to a deficit in T suppressive function on the production of antibodies.

Aged↗
PubMed1977

[Fibroblastic constrictive endocarditis. Apropos of a form localized in the left ventricle].

The authors report a case of a localised form of this strange disorder which was confined to the left ventricle, and in which the diagnosis was tentative for a long time. In this case it was possible to carry out a removal of the fibrous plaque after opening the apex of the left ventricle, the mitral valve being preserved, as described by Dubost; the functional and haemodynamic results of this procedure were very satisfactory.

Angiocardiography↗
PubMed1977

[Determination of first signs of pacemaker failure. Oscilloscopic study before and after removal].

An oscilloscopic study aimed at determining the first signs of pacemaker failure was carried out in vitro after removal in 95 cases. Using a differential apparatus with a 1 megahertz passing band, the following parameters were measured: interspike interval, amplitude, duration and morphology of the spike. During the course of the study, signs of pacemaker failure were seen in 66 cases. It may be concluded that the interspike interval represents the easiest and most precise measurement, making it possible alone to detect dysfunction in 70 per 100 of cases. However, in 30 per 100 of cases, represented by certain types of pacemaker, its alteration is preceded by a decrease in voltage. Whilst the latter may be precisely and easily measured in vitro, the same does not apply when the pacemaker is in situ and only large changes may be taken to be significant and interpreted in relation to the number of batteries in the model studied. Study of the vectrocardiogram should be added to the measurements mentioned above, any sudden change in axis of the spike being an argument in favour of a fault in the conductor. In the future, measurement of the area of the spike, a reflection of the energy delivered the histogram of the RR intervals giving an idea of the respective durations of function and of inhibition in demand models will provide additional information.

Humans↗