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Biomedical subjects

J Kermarec

Publications and source records attributed to J Kermarec.

At least 73 records · Page 4Linked to original sources

[Interventricular communication caused by nonpenetrating injury of the thorax].

Previously fatal in the majority of cases, traumatic interventricular communications are now curable by surgery. This is illustrated by the case described here of a 20 year old man. 62 other cases were found in the literature. A systolic murmur is the essential feature in diagnosis but it may be discovered some time after the accident. The demonstration of cardiomegaly has less diagnostic significance than ECG signs suggestive of an infarction. Haemodynamic studies are essential to confirm the diagnosis and to provide an accurate assessment of the lesion. The spontaneous course is serious since death results in two thirds of cases. Surgery is indicated, other than in well tolerated forms with a minimal shunt. The approach used has almost always been right cardiotomy. However, incision of the left ventricle offers better visibility of the lesions which may be masked by the papillary muscles when a right-sided approach is adopted. This was used in the present case with an excellent result since the patient was able to continue the military career for which he had opted.

Adult↗

[Determination of myocardial contractility using ultrasonic echography].

Ultrasonic echography makes possible the recording of movements of the septum and posterior wall of the left ventricle. On graphic records of good quality it is thus possible to measure accurately the transverse diameter of the left ventricle throughout systole and to determine the average and maximal speeds of decreases in this diameter, which are proportional to the VCF. Echography, a non-invasive technique, thus gives data with regard to myocardial contractility of similar value to the information provided by cineangiocardiography. In those cases where it is not possible to obtain such tracings, an approximation may be made, validity of which appears to be confirmed by clinical experience.

Cardiac Output↗

[Value of the determination of gamma glutamyl transpeptidase in the detection of hepatic metastases of bronch-pulmonary cancers].

The authors have dosed gamma glutamyl transpeptidase in 42 patients with primary bronchopulmonary cancer, of whom 14 had liver metastases. In these 14 patients the level of gamma glutamyl transpeptidase was always high, except in 1 case; while in the remaining lot, a moderate and mostly belated increase was noticed in only 32 percent of cases. The dosing of gamma glutamyl transpeptidase present some interest in the detection of liver metastases in primary bronchopulmonary cancers, specially when coupled with the dosing of alcaline phosphatase. Interpretation of results should take into account the existence of an associated liver-gall bladder involvement and of a recent surgical operation; both factors being capable of raising the level of gamma glutamyl transpeptidase.

Adenocarcinoma↗

[Pharmacodynamic study of myocardial contraction using ultrasonic echography during isoproterenol perfusion in the normal subject].

An echographic study, both before and under isoproterenol infusion, was performed on 50 normal subjects. The movements of the posterior wass of the left ventricle were found to be averagely increased of 62% as regards the amplitude, 114% for the mean speed and 124% for the maximum speed of contraction. The transcerse diameter of the left ventricular cavity decreased by 5.25%. The circumferential fibres shortening speed expressed in circumference by second increased by 128%. An uninvasive method, echography, as cineangiography, makes it possible to assess the myocardial contractility on the basis of measurement of the average speed of circumferential fibres and of the diameter of the left ventricle.

Adult↗