Biomedical subjects

J Kane

Publications and source records attributed to J Kane.

At least 181 records · Page 10Linked to original sources

PubMed1977

Trichophyton fischeri sp. nov.: a saprophyte resembling Trichophyton rubrum.

A new species Trichophyton fischeri was isolated as a contaminant on blood agar plates. This fungus is believed to be a saprophyte. It may be confused with T. rubrum. On peptone dextrose agar plate, the growth is white and velvety to cottony. It occasionally forms furrows. The underside of the mature colony is brownish red. Clavate microaleuriospores are common. Trichophyton-type macroaleuriospores are produced occasionally on blood agar and potato dextrose agar. Erythritol does not stimulate T. fischeri to produce a red color on casamino erythritol albumen agar. Closterospore-like projections may be produced on the main filaments on peptone dextrose and potato dextrose agar.

Trichophyton↗

PubMed1976

Tinea cruris: diagnostic confusion due to isolation of Candida albicans alone.

The diagnostic importance of the isolation of Candida albicans from a skin lesion is often uncertain. In a 68-year-old man from whose lesions only C. albicans was originally isolated Trichophyton rubrum and Epidermophyton floccosum were also isolated when the growth of the yeast was inhibited in a selective medium. The use of this selective medium, casamino acids erythritol albumin agar, ensures the proper interpretation of the significance of the presence of C. albicans in skin lesions.

Aged↗

PubMed1976

Tinea nigra infection in Canada.

The first infection of tinea nigra known to occur in Canada is reported. The infection occurred on the palm of a Canadian boy, 6 years of age, while he was visiting in the Bahamas. Cultural studies identified the causative fungus to be Cladosporium werneckii.

Canada↗

PubMed1976

Double-blind trial of labetalol.

1 A new anti-hypertensive agent (labetalol) with alpha- and beta-adrenoreceptor-blocking properties has been assessed in 30 patients in a general practice. 2 Significant reduction in blood pressure and pulse rate occurred at a dose of 400 mg/d. A further significant reduction in blood pressure but not of pulse rate occurred at a dose of 800 mg/d. 3 After 4 weeks' treatment on the higher dose the mean fall in systolic and diastolic pressures compared with the pre-trial pressures was 36 and 24 mmHg, respectively. Side-effects were generally mild.

Adult↗

PubMed1976

Occurrence of Trichophyton megninii in Ontario. Identification with a simple cultural procedure.

Five strains of Trichophyton migninii were isolated in Toronto from four people. One patient probably was infected in Toronto since he had not visited the European endemic area. These were the first isolates made in Ontario; a requirement for L-histidine was determined. A cultural differentiation of T. migninii and T. rubrum is described. Attention is directed to the similarity of the metabolism for dextrose in Bromocresol purple milk dextrose agar by T. megninii and T. mentagrophytes which differs from T. rubrum.

Adolescent↗

PubMed1975

The effect of sodium chloride on the growth and morphology of dermatophytes and some other keratolytic fungi.

A study of the influence of various concentrations of NaC1 on 21 species of dermatophytes and other keratolytic fungi was made. Based on the sensitivity of the species to various concentrations of NaC1, it was possible to divide them into five groups. Microsporum ferrugineum and Trichophyton concentricum and T. tonsurans were the most sensitive to NaC1 and were inhibited by 5%. The greatest number of species were inhibited by 12% NaC1. The fungi most tolerant to NaC1 were M. cookei and M. nanum, and T. mentagrophytes, T. schoenleinii, and T. terrestre. These species were inhibited by 15%. NaC1 prevented any variant change in Epidermophyton floccosum, T. mentagrophytes, and M. gypseum, but promoted a change in phenotype in M. audouinii and M. cookei, and T. gallinae. It is suggested that the word "pleomorphism" be replaced by the term sterile albinism. This term refers to that kind of cultural change when there is no evidence of sporulation and the white fluffy mycelium consists of fine sterile hyphae. Sterile albino strains of E. floccosum were induced to form a macroconidia on Sabouraud cycloheximide chloramphenicol gentamicin agar (SCCGA) containing 3-5% NaC1. Also, M. audouinii formed microconidia and macroconidia in velvety growth cultured on SCCGA containing NaC1.

Epidermophyton↗

PubMed1975