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Biomedical subjects

J Henke

Publications and source records attributed to J Henke.

At least 109 records · Page 6Linked to original sources
PubMed1978

HLA-antigens in idiopathic haemochromatosis (i.h.). preliminary report.

Striking differences could be observed when the HLA-antigens of 11 unrelated idiopathic haemochromatosis (i.h.) patients were compared with healthy controls. Besides the increase of the antigens A3, A11 and B7 and the decrease of A2, the large number of homozygous antigens at the A or/and at the B locus was found to be the most interesting result. Taking the latter finding into account, the possible existence of a recessive "disease-susceptibility gene" closely linked to the major histocompatibility system, playing a basic role in the etiology of i.h. was assumed.

Genes, Recessive↗
PubMed1978

A comparison of the N-terminal amino acid sequences of early and late pools of anti-DNP and anti-DNP-p-aminobenzoylglutamate antibody light chains.

The N-terminal amino acid sequences of early and late pools of anti-DNP and anti-DNP-p-aminobenzoylglutamate (DNP-ABG) antibody light chains were quantitatively determined and compared. The amino acid composition at each locus of the N-terminal 20 amino acid residues of each light chain preparation was determined using automatic sequencing techniques coupled with high-pressure liquid chromatography and mass spectrometry. The sequence data obtained for the light chains corresponding to antibodies isolated early in the immune response (3-4 weeks) were essentially the same as those for light chains from antibodies isolated late in the response (12-14 weeks). In addition, it was observed that the sequence data obtained for the anti-DNP antibody light chain preparation were almost identical to those found for two anti-DNP-ABG antibody light "hain preparations. The sequence data obtained in the present study were compared with those obtained for normal rabbit light chains and with the composite sequence data published for other rabbit anti-hapten light chains.

Amino Acid Sequence↗
PubMed1975

[Cross reactions of anti-E sera with the Rh antigens E and Ew].

Tests with 12 different trade anti-E sera have proven that half of them contain anti-Ew components. Therefore, according to the results of the tests, it must be concluded that, by immunizations with the antigen E, antibodies with the specificity anti-EEw are often be formed.

Antibody Specificity↗