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Biomedical subjects

J Henke

Publications and source records attributed to J Henke.

At least 91 records · Page 5Linked to original sources
PubMed1984

[Gm and Km allotype determination in fresh and putrefied dilute stomach extracts].

The authors were able to determine reliably Gm and Km allotypes in extracts of fresh human stomach. The results achieved in extracts of putrefied material, however, had a significantly increased rate of errors. Possibilities for those errors are discussed. A description for preparing the organs is given.

Blood Grouping and Crossmatching↗
PubMed1984

[Unusual Gm-haplotypes possibly due to crossing over].

Four cases are introduced with unusual Gm-haplotypes. Their possible origin is discussed as being either intra- and intergenic or unequal cross over. The last case shows deletions of either y1 or y3 -cistrons due to unequal cross over.

Crossing Over, Genetic↗
PubMed1984

Evidence for a "new" allele at the esterase D (E.C. 3.1.1.1.) locus.

An apparently new EsD gene product (EsD*Düsseldorf) was detected by use of horizontal agarose gel electrophoresis (AGE), starch gel electrophoresis (SGE), and isoelectric focusing (IEF). The observed phenotype EsD (1-Düsseldorf) can be distinguished from any known EsD type.

Alleles↗
PubMed1982

[Detection of Gm, Km, and EsD phenotypes in the dental pulp of human cadavers ].

Dental pulps of human cadavers (some of them putrefied) were investigated to determine the immunoglobulin markers G1m(1,2,3), G3m(5,10,21), Km(1), and the isozyme EsD. Reliable results were obtained in the Gm and Km typings, also in putrefied or skeletonized cadavers. EsD typings revealed that the phenotypes EsD(1) and EsD(2-1) are expressed in the dental pulp and can also be detected there in putrefied cadavers.

Carboxylesterase↗
PubMed1982

PGM1a subtyping in Western Germany (Düsseldorf region).

Phosphoglucomutase (PGM1a) subtypes were determined by isoelectric focusing on samples of 496 unrelated individuals. Ten phenotypes were observed as gene products of four alleles at the PGM1 locus, with the following gene frequencies: PGM1a1 = 0.631, PGM1a2 = 0.194, PGM1a3 = 0.126, and PGM1a4 = 0.049. A rare phenotype PGM1(8-a2) was observed.

Chromosome Mapping↗
PubMed1982

Subacute sclerosing panencephalitis in a brother and sister. Therapeutic trial of fibroblast interferon.

This paper describes the very rare occurrence of subacute sclerosing panencephalitis (SSPE) in two siblings: a Turkish boy and his younger sister. The clinical picture was characteristic, and the diagnosis was confirmed in both cases by appropriate laboratory examination. The interval between the occurrence of the first neurological symptoms in the boy, and subsequently in the girl was four years. Study of HLA- and 27 other polymorphic marker-systems did not reveal linkage to one of the systems tested. Therapeutic trials in the girl included intravenous and intraventricular application of a total of 87 X 10(6) U human fibroblast interferon (Hu INF-beta) over 21 days. However, up to 3 months after the end of interferon administration there were no significant changes in the girl's condition.

Adolescent↗
PubMed1981

Experimental studies on the kinetics of early postmortem decay of the lymphocyte membrane. Remarks about its application to forensic hemogenetics and to cornea transplantation.

Tests on human and animal cadavers were carried out to investigate the early postmortem decay of the lymphocyte membrane HLA-typing of cool-kept human cadavers can be performed within the first 36 h after death. Hereby, a possibility is obtained to determine HLA-ABC antigens of the deceased for hemogenetic or cornea transplantation purposes. The data obtained from animal experiments give evidence that the decay of the lymphocyte membrane follows a function of the Verhult's type. Using this function, it is possible to estimate the rate constant as a function of temperature.

Animals↗