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Biomedical subjects

J Chapman

Publications and source records attributed to J Chapman.

At least 433 records · Page 24Linked to original sources
PubMed1981

Secondary lambda attachment site in the threonine operon attenuator of Escherichia coli.

We have determined the nucleotide sequence of a secondary gamma attachment (att) site which overlaps the Escherichia coli threonine (thr) operon attenuator. The secondary att site shows uninterrupted homology (8 out of 15) with the 15 base-pair "common core" sequence found in gamma and at the primary bacterial attachment site. These 8 base paired also overlap the thr operon attenuator. Comparison of the secondary att site with the flanking prophage sites shows that the crossover site for gamma integration lies within the -7 to 0 region of the core. Sequences on both sides of the core show no obvious homology with analogous sequences of the gamma or primary bacterial att sites. The core sequences of the left prophage att site is completely homologous to the wild-type core and also shows the same 8-base pair overlap with the thr operon attenuator. The position of the thr operon attenuator, relative to the left prophage att site, indicates that ribonucleic acid transcripts, initiated at a gamma promoter, are terminated efficiently at the thr attenuator. It is also possible that this prophage att site is able to undergo int dependent site-specific recombination which with another nearby secondary att site. Evidence is also presented which suggests that a base or sequence to the left of position -6 in the core is necessary fo excisive recombination.

Attachment Sites, Microbiological↗
PubMed1979

Decision versus policy in crises intervention.

The paper describes procedures for contrasting actions taken by crises intervention outreach workers and consumers with administrative policies. The data used to exemplify the procedures came from the outreach projects of six county MH/MR programs in Central Pennsylvania during the year following the flood caused by Hurricane Agnes, in 1972. The procedure identifies and counts the ways through which consumers entered the outreach process; the major outreach worker decision; and the immediate disposition of each consumer's case. The six county MH/MR program administrators were asked to consider program policies and show how they would ideally expect 1,000 hypothetical consumers to come into, to be processed through, and to be referred out of their respective outreach programs. Contrasts of the ideal and actual consumer data, along with consumer follow-up questionnaires, provided the basis for evaluating the six county MH/MR program outreach projects. These experiences provided the basis for a generalized model of evaluating crises intervention activities.

Counseling↗
PubMed1979

Haematological features of angioimmunoblastic lymphadenopathy with dysproteinaemia.

A study of seven patients with AILD has confirmed previously reported cytological and immunological changes in the peripheral blood. In themselves these changes should not be considered as specific. Histological examination of the bone marrow may show more characteristic lesions which involve haemopoietic, lymphoid, and stromal cells. Three patients had bone marrow features similar to myelofibrosis, which are considered to be diagnostic of AILD.

Aged↗
PubMed1979

The treatment of ACTH Paraneoplastic syndrome with aminoglutethimide.

A 60-year-old white female with oat-cell carcinoma of the lung presents with a recurrent pulmonary nodule and Cushing syndrome. The tumor is uncontrollable with MeCCNU and cyclophosphamide (Cytoxan), consequently the symptoms of Cushing disease become severe. Cushing syndrome is documented by laboratory examinations. Aminoglutethimide, an anticonvulsant, is used to reverse the symptomatology and also the laboratory values. When aminoglutethimide is discontinued, the laboratory findings return to pretreatment levels.

Adrenocorticotropic Hormone↗
PubMed1978

Exposure of council and forestry workers to 2,4,5-T.

The exposure of council and forestry workers to 2,4,5-T, a plant poison, has been monitored for a period of two years. It was found that the excessive urine levels of 2,4,5-T fell dramatically once the exposure was minimized. Therefore, the use of protective clothing and adoption of measures to prevent inhalation exposure are essential.

2,4,5-Trichlorophenoxyacetic Acid↗
PubMed1977

An intensive support unit for parent-infant distress.

Integration of the young infant with his parent(s), in the days and weeks after birth, should be as stress free as possible. In many families considerable distress is experienced in the parent-infant relationship. There is increasing evidence that distress of significant degree may have complex sequelae, particularly for the infant, and may affect growth and development in many areas. Child abuse is another expression of this distress. A unit aimed at providing intensive support for such distressed situations is described and evaluated on a short-term basis. The evaluation suggests that this unit is successful in alleviating many of the outcomes of such situations.

Attitude to Health↗
PubMed1977

Closed catheter drainage and urinary infection--a comparison of two methods of catheter drainage.

The incidence of urinary infection following urological operations is compared using 2 methods of closed catheter drainage in 214 patients. No significant difference was observed. The overall infection rates for the whole series were 32%. The most significant influence on the rate of infection appears to be the duration of catheter drainage. Failure of chemotherapy to eradicate infection while the catheter was still in situ was mostly due to the use of inappropriate antimicrobials. Only 2 of the 35 cases with infected urine had succeeded in clearing their infection at the 4-week follow-up without chemotherapy.

Adolescent↗
PubMed1977

The Kveim test.

Explore the source record for details and available documents.

Antibodies↗
PubMed1977

Management of an infected Hancock prosthesis after repair of truncus arteriosus.

This report described a case in which purulent mediastinitis involving a Hancock prosthesis developed after repair of truncus arteriosus in a 6-year-old boy. The graft and surrounding area became sterilized after having been irrigated with povidone-iodine and antibiotic solutions for 6 weeks. At his most recent visit, the child was completely active and asymptomatic.

Animals↗
PubMed1975

Child's play is therapy.

Play can be a simple, effective way of helping the preschool child to deal with the strange and sometimes painful hospital world and to master situations that might otherwise be overwhelming. This type of play can be incorporated easily into the nursing care plan and can become an essential aspect of the care of the hospitalized preschool child. The results are rewarding in terms of happier, less anxious children, parents, and nursing staff.

Adaptation, Psychological↗