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Biomedical subjects

I Macnab

Publications and source records attributed to I Macnab.

At least 55 records · Page 3Linked to original sources
PubMed1970

The use of chymopapain in degenerative disc disease: a preliminary report.

On the basis of the early results of the use of intradiscal injection of chymopapain in 15 patients with degenerative lumbar disc disease, the following statements are warranted: The injection can be beneficial in selected patients with lumbar disc disease. The relief of leg symptoms seems to be more striking than that of the accompanying low back symptoms although both are apparent. The exact mechanism by which pain is relieved is still obscure, but helpful information has been obtained from the early results of this investigation. The failure of chymopapain in carefully selected patients has resulted in only a brief time delay in operative intervention.

Adult↗
PubMed1969

Value of pre-employment radiographic assessment of the lumbar spine.

In order to test the hypothesis that pre-employment radiographic examination provides information which permits identification of individuals who are likely to develop symptoms of lumbar pain under the stress of physical labour, the study reported was undertaken. Two groups of male labourers of minimum age 35 years were matched for important variables, and differentiated by the circumstance that one group alone had the additional characteristic of a positive history of lumbar disability. Study of the radiographs of these subjects allowed tabulation of all deviations from normal, both minor and major. A computerized comparative analysis was performed on the data. It was found that there is no developmental or degenerative change or combination of such changes which has predictive value when applied to the individual. Therefore, since this examination provides no legitimate criteria for prognostication, the hypothesis as stated is invalid, and the worth of the policy of pre-employment assessment is open to serious question.

Adult↗