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Biomedical subjects

I Macnab

Publications and source records attributed to I Macnab.

68 records · Page 4Linked to original sources

The pathophysiology of the anterior tibial compartmental syndrome.

Based on a clinical review of 45 patients with acute anterior tibial ischemia, four different conditions were identified. Three were related to increased pressure within the compartment and were called anterior compartmental syndromes. They followed exercise, trauma, and ischemia. The fourth entity was anterior tibial ischemia due to anterial occlusion. An experimental investigation demonstrated that increased pressure within the anterior compartment slows blood flow to the enclosed tissues.

Anterior Compartment Syndrome↗

Observations on eburnated bone.

Eburnated bone in osteoarthritic joints has been examined with the Scanning Electron Microscope to investigate the cause of the bone loss which occurs at the joint surface in this condition. In eburnated bone the lamellae surrounding the Haversian canals can readily be seen. After artificial abrasion the surface is flat and featureless. After treatment with agents which leach out some of the ground substance the lamellae can again be seen. These observations indicate both corrosive wear and abrasive wear play a part in producing eburnation.

Humans↗

Localization of symptomatic lumbar pseudarthroses by use of discography.

Twenty-four patients with lumbar pseudarthroses following attempted fusion were investigated by preoperative discography. The pseudarthroses were confirmed at surgical exploration. In 19 patients, discography at the level of a pseudarthrosis reproduced typical back pain, and in two patients the level above the fusion reproduced typical pain. Discography is not indicated when the major symptoms are leg or buttock pain. Technical errors included injection into the annulus fibrosis and impingement of the needle into the vertebral endplate. The latter may produce a false-positive result. Previous posterior fusions and very narrow disc spaces prevented insertion of the needle in some patients. Not all lumbar pseudarthroses were symptomatic, and two frequently occurred in the same patient. Discography is a useful adjunct to the traditional investigation of lumbar pseudarthroses.

Adult↗

The Fabella Syndrome.

The Fabella Syndrome is recognized by a sharp pain, local tenderness, and intensification of pain in the area of the fabella by full extension of the knee. After diagnostic tests with local anesthesia and ineffective conservative treatment, surgical extirpation may produce lasting relief of symptoms.

Adolescent↗