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Biomedical subjects

I Macnab

Publications and source records attributed to I Macnab.

At least 37 records · Page 2Linked to original sources

The microhardness of articular cartilage.

The standard metallurgical technique of microhardness testing was useful for investigations on the physical properties of articular cartilage. The problem of visco-elasticity of the cartilage was overcome by using a brittle lacquer coating as a memory device. The surface layer was the hardest plane when the superficial layer was intact. Removal of the superficial layer however, made this plane the softest. There was no variation in hardness with depth. The plane at right angles to the vector of movement of the joint was harder than the plane parallel to the vector of movement. This indicates the presence of a secondary fiber system in the middle layer of articular cartilage. The fibers in this system run predominantly at right angles to the direction of motion of the joint.

Cartilage, Articular↗

Cervical spondylosis.

Cervical disk degeneration (CDD) can give rise to segmental instability and may appear as pain referred to the arm without any evidence of root compression. CDD can give rise to root pressure either by permitting the development of a disk rupture of by provoking the development of a neurocentral osteophyte, compressing the root in the root canal. Such osteophytes may also compress the vertebral artery. Primary treatment is always conservative. When operative intervention is necessary an anterior cervical discectomy and fusion is preferable to a posterior decompression.

Analgesics↗

Porous surface layered prosthetic devices.

The method of fabrication and properties of a dual structured implant system consisting of a metallic porous surface layer is described. The ingrowth of bone tissue into the outer porous surface layer results in part fixation, while the solid inner core region provides the necessary mechanical strength for a device used for the replacement of heavy load bearing joint regions such as the hip and knee. Additionally, novel implant systems are suggested using the porous coating concept.

Animals↗

Use of polymethylmethacrylate to enhance screw fixation in bone.

Pull-out testing of screws inserted into cement and bone under various conditions showed that the cement-screw complex was significantly stronger when the screw was placed in soft cement and the cement was allowed to polymerize without further manipulation. When screw fixation in osteoporotic bone was reinforced with cement, the bone was the weakest component in the system. Fixation under these conditions should be enhanced by increasing the area of contact between the cement and bone. By cooling the cement to prolong its working time, it could be injected with a syringe in such a way that maximum endosteal and periosteal contact was provided.

Bone Cements↗