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Biomedical subjects

H Wang

Publications and source records attributed to H Wang.

At least 1,675 records · Page 93Linked to original sources
PubMed1997

[Audiologic measure in Ménière's disease].

To determine some audiologic phenomena of Ménière's disease before and after ingestion of dehydration agent and evaluate its diagnostic value, 48 ears of Ménière's disease, 40 ears of other vertigo disease and 40 normal ears were investigated. The measures were undertaken before and after glycerol or urea ingestion, which included threshold of pure tone audiometry, peak static acoustic admittance (Ya) and conductance(Ga) at probetone signal of 678 Hz, peak compensate static admittance(delta Y) and conductance(delta G) at resonance frequency, -SP/AP, and width of SP-N1 in ECochG. Results showed that abnormal rates of glycerol group and urea group were similar, and there was no significant statistical difference. So these two groups were combined together as one in statistics. The rate of totally abnormal ears were 17/32 in seven measures. Abnormal rates of dehydration test were: pure audiometry 66.67%, Ga 62.50%, -SP/AP 52.08%, width of SP-AP N1 66.67%. chi 2 test showed no significance statistical difference among these results. It indicated that these measures had same diagnostic value for the Ménière's disease. The shift value of G a and delta G of dehydration test might be as the objective diagnostic methods of Ménière's disease.

Acoustic Impedance Tests↗
PubMed1997

[Significance of endocrine cells and their hormones in colorectal cancer].

OBJECTIVE: To analyse the expression and clinical pathologic significance of endocrine cell (EC) and their hormones in colorectal cancer (CC). METHODS: Chromograin A (CGA) and five kinds of hormones in 117 cases of CC were detected by immunohistochemistry with 13 observed by electron microscopy. RESULTS: CGA positive cells (EC) occurred in 46 cases (39.3%). 69.2%(27/39) expressed more than one hormone. The lymph node metastasis rate (68.0%) in the EC-positive CC was higher than EC-negative CC (43.7%) (P < 0.05). The incidence of EC(+2) in CC with morderative and poor differentiated (25.5%) was higher than well differentiated (P < 0.05). EC-positive CC gave shorter survival. It's an independent factor for evaluating prognosis in CC. The expression of 5-HT, GLU, GAST and beta-HCG occurred more offen in tumor with moderate and poor differentiation giving poor prognosis (P < 0.05). Cancer cells containing endocrine granules were found in 8 cases of CC by electron microscopy. The two methods were comformable in 92.3%. CONCLUSION: EC-positive CC has poor histological differemtiation, giving rise to more lymph mode metastasis and poor prognosis. Some hormones secreted by EC could partly account for the growth and metastasis of CC.

Adenocarcinoma↗
PubMed1997

[Continuity and changes of breeds of fupenzi].

Based on textual researches, it has been confirmed that Fupenzi first appeared in Han Dynasty. Both Fupenzi and Penglei had the same origin, but split up during Jin Dynasty into two different breeds. Through ages Fupenzi has been taken as the fruits of the plant Rubus of Rosaceae species. Among them, R. idaeus, R. corchorifolius and R. coreanus have long been in use. R. chingii is the new breed of modern Fupenzi.

Conservation of Natural Resources↗
PubMed1997

Potassium channels on cardiomyocytes of selenium iodine deficiency rats and iodine deficiency rats.

Using diet control method to feed the weaning male Wistar rats with selenium and iodine deficiency Keshan endemic area food for 8 weeks to set up animal model. Singal channel recording in cell attached model was used to measure cardiac cell membrane potassium channel conductances, which coincide with the cardiac cell membrane potassium channel conductances in normal Wistar rats. The potassium channel conductance on selenium and iodine deficiency rat cardiac cell membrane is showing current-voltage increasing lineally in the range of clamping voltage 0 +/- 30 mV with channel conductance of 43.4 pS. The channel current does not increase depending on the clamping voltage that is showing the rectifying characteristic and the channel current amplitude can be augmented by added KIOa 5 mmol/L in bath solution. A kind of inward rectifying potassium channel activity was recorded, but this channel activity disappeared after lasting 6-10 minutes only. Then an inward rectifying potassium channel with the conductance of 14.2 pS was activated by KIOa 5 mmol/L introduced to bath solution. Both conductances are less than that of normal Wistar rats.

Animals↗
PubMed1997

[Pharmacological effect of cortex Magnoliae officinalis on digestion system].

Experiments have shown that the ethanol extract of Cortex Magnoliae Officinalis 5 g/kg, 15 g/kg may significantly inhibit HCl-induced gastric ulcer in mice as well as Cassia angustifolia Leaf-induced experimental diarrhea in mice. 3 g/kg and 10 g/kg have a marked choleretic effect on rats. These results show that Cortex Magnoliae Officinalis helps improve the condition of digestion.

Animals↗
PubMed1997

[Effect of electric field on erythrocyte sedimentation rate. VI--dependence of electric field pattern].

An automatic analyzer of RBC rheological parameters and a microscopic morphological observation technique were employed to investigate the effect of three electric field patterns on erythrocyte sedimentation and aggregation in a physiological saline solution and in autologous plasma, respectively. Experimental results indicate that in a physiological saline solution: 1) Erythrocytes present a lightly aggregation and settle faster by an alternative current electric field; 2) There exists no erythrocyte aggregation by a direct current electric field of constant current and the enhancement of erythrocyte sedimentation is caused only by the action of electric force; 3) Time courses of erythrocyte sedimentation fit well with an exponential type curve by a direct current electric field of constant voltage, and this exponential type sedimentation curve is not caused by erythrocyte aggregation but caused by the decrease of circuit current with time duration. Also shown by experimental results is that the above three electric field patterns all affect the erythrocyte sedimentation in antologous plasma in different contents, which predicts some change in erythrocyte aggregation behavior in autologous plasma by an external electric field.

Blood Sedimentation↗
PubMed1997

The long-term effect of captopril treatment on endothelial function in spontaneously hypertensive rats.

The aim of this study is to elucidate the long term effect of captopril treatment on the endothelial function to release nitric oxide (NO) in spontaneously hypertensive rats (SHR). The properties of endothelium were determined with a model of hindquarter perfusion in response to alpha 1 adrenergic agonist, phenylephrine, at the age of 40 weeks of SHR which was administrated with captopril (100 mg/kg/day) from intrauterine and withdrawn at 16 weeks of age. Furthermore, in the presence of N omega-nitro-L-arginine methyl ester (LNAME), or L-arginine, the responses to phenylephrine were studied. From the curve of perfusion pressure, the minimal, maximal perfusion pressure (PPmin, PPmax) and the maximal slope (slope), as well as the 50% of effective concentration (EC50) were obtained. The data show that in captopril treated SHR, PPmin, PPmax and slope were markedly lower, but EC50 higher than those of untreated SHR. The curve induced by phenylephrine was significantly right shift compared with that of untreated SHR. Like WKY, the intensive reactivity to phenylephrine in the presence of LNAME was much lower than that of untreated SHR. In the presence of L-arginine, however, the right shift of curves was seen only in captopril treated SHR and WKY rats, but not in control SHR. In conclusion, endothelium does involve in the response of resistant vessel to phenylephrine. The mechanism of enhanced reactivity in untreated SHR may be, at least in part, due to the diminished capacity of producing NO from endothelium, and the effect of sustained hypotension of early captopril treatment might be relevant to the improved ability of endothelium.

Angiotensin-Converting Enzyme Inhibitors↗
PubMed1997

[Research on bond strengths of Vita II and plat II ceramic bonding to teeth].

This study compared the tensile bond strengths of Vita II machinable ceramic and Plat II castable ceramic bonding to teeth with three resin cements. The three adhesive cements were Vita cerec, Panavia 21 and TF adhesives. The results showed: 1. The Vita cerec was a good adhesive for Vita II ceramic bonding to enamel and dentine, the bond strengths were 8.91 MPa and 8.48 MPa; 2. The Panavia 21 was suitable for Plat II ceramic bonding to enamel and dentine, the bond strengths were 10.92 MPa and 7.13 MPa respectively. And it was also a good adhesive for Vita II ceramic bonding to enamel, the bond strength was 7.48 MPa; 3. TF had poor adhesive effects for both ceramic materials.

Dental Bonding↗
PubMed1997

[Marginal fit of CAD/CAM ceramic inlays].

The purpose of this in vitro study was to investigate the marginal and internal fit of Cerec-2 inlays before and after adhesion. The test showed: 1. Before luting, the axial marginal space was 67 +/- 18 microns, cervical marginal space was 84 +/- 22 microns and the mean occlusal marginal space was 58 microns. 2. After luting, the thickness of the luting composite was 118 +/- 37 microns at axial margin, and 123 +/- 17 microns at cervical margin, the mean occlusal margin space was 80 microns. This study demonstrated the marginal adaptation of Cerec-2 inlays satisfied the clinical demand, especially at occlusal margin.

Computer-Aided Design↗
PubMed1997

[A biomechanical study on the bone repairing ability of recombinant human bone morphogenetic protein-2-coral composited artificial bone].

To improve bone repairing ability of coral, recombinant human bone morphogenetic protein-2 (rhBMP-2)-coral composited artificial bone was obtained by combining coral with rhBMP-2 in this experiment. The composite was implanted into rabbit calvarial critical-size defects and coral alone was implanted as control. The bone repairing ability was assessed by radiography, histology and biomechanics. The results showed that implants were absorbed gradually after they was implanted into the defects. In the meantime, the new bone was formed and the mechanical strength was reinforced uninterruptedly in bone defect regions. At 12 weeks, the implants were replaced completely by bone, and the mechanical strength was entirely restored. These suggest that the composite possess a superior bone repairing ability and may be one of the most perfect bone graft substitutes currently available.

Animals↗
PubMed1997

[An experimental study of the growth pattern and mechanisms of surgically induced cleft palate and palatoplasty on maxillary growth in dogs].

The authors observed the changing process of length, width and height of maxillary growth in experimental animals, the experimental animals were divided into the unoperated control group, the surgical induced cleft palate group, the repaired cleft palate group and the group of implanted autograft bone in total hard palate. The method of a serial dorsoventral and lateral cephalograms were used in the study. The experimental result showed: the rate of maxillary growth began to change from two to four weeks and finished in the eighteenth week after operation. There was a remarkable different rate of maxillary growth among the four groups. The track of premaxillary growth had a difference between unoperated control group and the others. The experimental result suggested that the direction of growth in nasal septal cartilage and the conduction of force from premaxillary to maxillary were inhibited. It is a main reason for maxillary growth disturbance of the cleft palate who had or had not surgery.

Animals↗
PubMed1997

[An experimental study of the influence and mechanism of surgically induced cleft palate and palatoplasty on teeth and dental arch in dogs].

The dogs were selected as the experimental subjects in this study. The authors continuously observed the maxillary teeth and dental arch form in preoperation and 2, 4, 6, 10, 14, 18, 22, 26, 30, 34 weeks of post operation to all the animals. 40 puppies were divided into four groups, which were unoperated control group, surgically induced cleft palate group, cleft palate repaired group and cleft palate implanted bone group. The experimental result showed: there were remarkable differences at rate of itself growth between deciduous dentition and permanent dentition in the four groups. The result suggested that the cleft palate was a reason for disturbances of dental arch development, an exposed bone wound in hard palate of maxillary after palatoplasty was an important reason that it made maxillary dental arch growth problem heavier, authors could prevent the disturbs the transverse development of the maxillary dental arch from cleft palate who had or had not repaired by implanted bone in total cleft palate.

Animals↗
PubMed1997

[Antagonizing effect of sodium ferulate on the changes of hepatic antioxidative function induced by ethanol in mice].

Effects of ethanol at different dosages on hepatic antioxidative and detoxicating functions and the antagonizing effect of sodium ferulate have been investigated in mice. The data showed that ethanol (11.4 g.kg-1, ig) could induce the increase of hepatic glutathione peroxidase (GSH-Px) activity and decreases of hepatic glutathione reductase (GSH-Re), superoxide dismutase (SOD) and glutathione S-transferase (GST) activities and reduce glutathione (GSH) content. At the same time, serum GST activity was increased. Pretreatment with sodium ferulate (100 mg.kg-1 ig, qd x 10 d) completely reversed these changes induced by ig ethanol in mice, indicating that sodium ferulate could protect mice from ethanol-induced acute hepatotoxicity. The hepato-protective mechanism of sodium ferulate may be related to intensification of the function of glutathione oxidative-reductive enzymes, enhancement of SOD activity and promotion of glutathione conjugation. The results also indicate that the serum GST level is a sensitive indicator in ethanol-induced hepatotoxicity.

Animals↗
PubMed1997

[Constituent analysis of the essential oil in leaves of Torreya nucifera].

The constituents of the essential oil in leaves of Torreya nucifera (L.) Sieb. et Zucc. (EOLTN) in China were firstly analysed by GC-MS-DS. 68 of the 71 separated constituents in EOLTN were identified. The total contents of identified constituents accounted for 96.364% of EOLTN.

Bicyclic Monoterpenes↗
PubMed1997

[Primary study on Fas-mediated apoptosis in the liver tissue of patients with chronic hepatitis B].

Apoptosis may be the cause of cell death that activate gene due to certain factors. It has been suggested that apoptosis is mediated through Fas antigen. To evaluate the role of the Fas antigen and apoptosis in chronic hepatitis B (CHB), we observed the Fas expression and nuclear DNA fragement in CHB hepatic tissue using immunohistochemistry and TUNEL method respectively. The results showed that the Fas antigen expressing cells located mainly in inflammation infiltrating area but less in non-inflammation infiltrating area; the positive cells were found particularly among infiltrating lymphocytes at the advancing edges of "piecemeal necrosis" near the portal regions. The expression of Fas was detected mainly in the cytoplasm of hepatocytes. 46 samples from 56 CHB patients were Fas positive, the posive rate reached 82%. The Linear Correlation and Regression analysis suggested that there was a direct correlation between nuclear DNA fragement and Fas expression. These findings suggest that the apoptosis mediated through Fas antigen may play an important role in pathogenesis of CHB.

Adolescent↗
PubMed1997

[Investigation on hepatitis G virus (HGV) infection among different populations in Shenzhen].

A reverse transcription polymerase chain reaction assay with nested primers (RT-nested PCR) deduced from the 5' untranslated region of HGV genome was established to detect HGV RNA. By using this assay, we tested the serum samples of 106 paid blood donors, 80 intravenous drug users and 168 cases with viral hepatitis in Shenzhen, China. The positive rates of HGV RNA were 8.5%, 46.3% and 7.7%, respectively. The positive rates of HGV RNA in 61 cases with chronic hepatitis B and 33 cases with chronic hepatitis C were 8.2% and 21.2%. Among the 33 cases with chronic hepatitis C, the positive rate of HGV RNA in 15 cases infected with HCV by blood or blood products was 40.0%, compared with 1.7% in 18 cases without exposure to blood or blood products (P<0.05). The results of this study suggest that HGV infection is common in paid blood donors; the intravenous drug user is the population at high risk for HGV infection; the patients with post-transfusion chronic hepatitis C are often supperinfected with HGV.

Adult↗