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Biomedical subjects

H W Bauer

Publications and source records attributed to H W Bauer.

At least 55 records · Page 3Linked to original sources
PubMed1982

[Bilateral stage nephrectomy as a preparation for kidney transplantation].

The indication for nephrectomy prior to kidney transplantation has changed. Contrary to the formerly in nearly all transplantation centres practiced one-time two-sided nephrectomy, at present the removal of the patient's own kidneys prior to transplantation is done only if strictly indicated. In contrast to other transplantation centres which, if indicated, still today carry out bilateral nephrectomy prior to transplantation is done only if strictly indicated. In contrast to other transplantation centres which, if indicated, still today carry out bilateral nephrectomy prior to transplantation, since 1977 the transplantation centre of Munich prefers the two-time bilateral nephrectomy. Technique, surgical approach, indication and results of our method are presented. In the course of the discussion the disadvantages of the one-time bilateral nephrectomy are opposed to the advantages of the two-time method.

Candidiasis↗
PubMed1982

Intravesical ultrasound tomography in staging bladder carcinoma.

The staging of bladder carcinoma is most important for treatment and prognosis. Transurethral ultrasound scanning was done with a rotating 6 MHz. transducer interchangeable with the optic of a 24F cystoscope. Intravesical ultrasound tomography and computerized tomography were used to treat 28 patients with bladder carcinoma. The correlation between ultrasound and histopathological findings showed that local staging of bladder carcinoma is possible by transurethral scanning.

Humans↗
PubMed1982

[Operative management of spontaneous kidney transplant rupture. Personal experiences and literature review].

Spontaneous rupture of the cadaver kidney is not rare in the early post-transplant period. In the literature the rupture complication rate varies between 0.3% and 8.5%. in our series 4.2% (12 of 285) of transplanted kidneys ruptured spontaneously. All transplant ruptures occurred as an early complication within 6 weeks postoperatively in the clinical setting of oliguria. In 8 of 12 patients we tried to preserve the graft by covering it with dehydrated solvent-dried human dura that is then sutured in place. In these cases surgical repair resulted in diuresis and restoration of normal graft function with long-term survival. This study emphasizes the possibility and necessity of conservation and repair of the ruptured allograft.

Adolescent↗
PubMed1982

[Organizational and technical aspects of organ removal].

The only efficient way to obtain adequate numbers of kidneys for transplantation is to perfect the technical and organisational method or organ harvesting. Careful attention to the details of organ procurement is as essential to the outcome of the transplantation as the procedure itself. To obtain optimal results, an effective collaboration between the central and peripheral hospital is necessary. A mobile medical and surgical team, coming from the central hospital for donor procurement was found to be most effective. Success in a major transplantation program requires continued improvement in the relationship between peripheral hospital physicians and the central transplant unit.

Brain Death↗
PubMed1981

The pregnancy-associated alpha 2-glycoprotein (alpha 2-PAG). A tumour marker?

Long-term studies of alpha 2-PAG in sera of patients with breast cancer, bronchial carcinoma, gynaecological carcinoma, melanoma and laryngeal carcinoma have proved that alpha 2-PAG is a possible laboratory parameter for the assessment of recurrence of tumour and metastasis. The results published for trophoblastic tumour and gastrointestinal carcinoma are still divergent. Because of the large individual range of alpha 2-PAG concentrations and the widely differing alpha 2-PAG levels in men and women single determinations of this protein are without value. A detailed classification of the pathological mechanisms to which these proteins are submitted is still missing and consequently we have no fundamental knowledge of diseases that apart from pregnancy and neoplasia lead to changes in the physiological alpha 2-PAG serum concentration.

Bronchial Neoplasms↗
PubMed1981

Enzyme immunoassay for the prostate-specific acid phosphatase (E. C. 3.1.3.2).

The clinical application of enzyme immunoassay for the determination of the prostate-specific acid phosphatase is reported. 227 sera were investigated in the diagnosis as well as in tumour monitoring and a good correlation with the clinical stage was found. In prostatic carcinomas 5 of 13 with stage T1, 11 or 12 patients with stage T2, 16 of 16 patients with T3 and 19 of 19 patients with stage T4 disease had values above 1 ng/ml. In prostatic adenomas (n = 69) in prostatitis (n = 40) and in other carcinomas of the urogenital tract (n = 28), renal carcinomas, carcinomas of the bladder and the penis) the values of the prostate-specific acid phosphatase measured by the enzyme immunoassay 131 of 137 were under 1 ng/ml. A comparison of random samples with the radioimmunoassay for this enzyme showed good correlation.

Acid Phosphatase↗
PubMed1981

A new technique for percutaneous nephropyelostomy.

Primary insertion of a large caliber catheter into the renal pelvis would provide the most favorable drainage in all cases in which urinary diversion by nephropyelostomy is indicated. Therefore, the puncture technique of Guenther and associates was modified. A specially designed balloon catheter was used to prevent dislocation.

Drainage↗
PubMed1981

[Diagnosis and follow-up of prostatic cancer using an enzyme immunoassay for prostate-specific acid phosphatase].

The clinical application of an enzyme-immunoassay for the determination of the prostate-specific acid phosphatase is reported. By this method 615 plasma probes of patients with prostata adenoma, prostatitis, prostatic cancer and other urological cancer were investigated. Whereas the enzyme-immunoassay showed good correlation with the follow-up of prostatic cancer especially when metastases grow on, the test is not yet sensitive enough to find out early prostatic cancer with reliable accuracy.

Acid Phosphatase↗
PubMed1980

[Determination of depth of infiltration of of vesical tumors by intravesical ultrasonic tomography (author's transl)].

A prerequisite for the therapeutic procedure in bladder carcinoma is the determination of the depth of infiltration and extent of the tumor. This is possible by means of intravesical ultrasonic tomography as studies in 19 patients with vesical tumors of different sizes and extent showed. Histologically verified infiltration depths correlated with the intravesical ultrasonic findings in all cases so far. A statement on the percentage accuracy of the sonographic findings is not yet possible because of the small number of cases so far.

Humans↗
PubMed1980

[Determination of acid phosphatase in prostatic carcinoma].

Serum acid phosphatase activity is the most commonly measured biochemical marker for diagnosing prostatic cancer and monitoring responses of such patients to therapy. Increased total serum acid phosphatase activity has been detected in the serum of up to 75% of patients with advanced disease (Stage D) which has metastasized to the bone, whereas in early stages (Stage A and B) as few as 10% may have increased total serum acid enzyme phosphatase values that can be detected by conventional biochemical assays. Serum acid phosphatase is believed to be comprised of specific molecular variants (isoenzymes) from sources throughout the body. Unfortunately, biochemical tests may lack specificity and sensitivity for the prostatic acid phosphatase, which is, thought to enter the serum in early stages of prostatic cancer. This situation prompted the development of immunologic assays for the determination prostatic acid phosphatase (radioimmunoassays, enzyme-immunoassays) which, it is hoped, combine the specificity achieved with immunologic reagents and techniques with the sensitivity made available through the use of radioisotopes or spectrophotometers.

Acid Phosphatase↗
PubMed1980

[Pregnancy,-associated alpha 2-glycoprotein (alpha 2-PAG): a possible marker for tumor monitoring?].

To comment on the recurrence of tumours and metastasis the long term studies of the alpha 2-PAG determination in sera of patients with carcinoma of the breast, bronchial carcinoma, gynaecological carcinoma, melanomas have proved as a possible laboratory parameter. The results published till the present time on trophoblastic tumours and gastrointestinal carcinoma are still divergent. Because of the large individual range of alpha 2-PAG concentrations and because of the widely differing alpha 2-PAG levels in men and women single determinations of this protein are without value. Still missing is a detailed clarification of pathological mechanisms to which this protein is submitted and thereby a fundamental knowledge of diseases which lead apart from pregnancy and neoplasiae to changes in the physiological alpha 2-PAG serum sample.

Breast Neoplasms↗