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Biomedical subjects

H W Bauer

Publications and source records attributed to H W Bauer.

At least 37 records · Page 2Linked to original sources
PubMed1986

Bilateral testicular germ cell tumors. Report of nine cases and review of the literature.

In a series of 181 patients with testicular germ cell tumors, the phenomenon of bilateral involvement of the testicles was observed nine times (5%). Two patients evidenced a simultaneous bilateral tumor, and, in seven others, a second tumor occurred after an interval ranging between 8 months and 6 years and 11 months. The incidence, histologic findings, therapy, and prognosis of bilateral testicular tumors are discussed on the basis of a survey of the literature. Emphasis is placed on the significance of a long-term follow-up period as well as on the important role of sonography in the early detection of a contralateral tumor.

Adolescent↗
PubMed1986

Prophylaxis of complications after urological abdominal surgery by substitution of plasma proteins.

A prospective randomized trial on 94 patients undergoing urological-abdominal surgery has been carried out to evaluate the effect of postoperatively administered plasma proteins. A significant difference in the incidence of bronchopulmonary complications has been found between the treatment group and the control group. This may be due to the substitution of alpha 1-antitrypsin as indicated by assaying alpha-antitrypsin activity. A positive trend, but no significant differences, could be demonstrated for wound healing and the need for antibiotics, postoperatively.

Anti-Bacterial Agents↗
PubMed1986

[Prostaglandin E2 in prostatitis and prostatic adenoma].

The measurement of prostaglandin E2 (PGE2) concentrations in the serum and prostatic fluid of healthy men, patients with prostatic hyperplasia and of patients with prostatitis was attempted and correlated to the state of disease, respectively. PGE2-concentrations with prostatic fluid of healthy men were found to be significantly lower than in patients with prostatitis. Corresponding to the course of treatment concentrations normalized, being favorably influenced by sitosterin as an adjuvant medication. Compared to healthy men, PGF2 concentrations in the prostatic fluid of patients with hyperplasia of the prostate incline to lower levels.

Adult↗
PubMed1985

Steroid hormone regulation of prostatic acid phosphatase expression in cultured human prostatic carcinoma cells.

We have investigated the modulation of prostatic acid phosphatase expression in the human prostatic cancer cell line LNCaP in response to the natural androgens testosterone and dihydrotestosterone, the female sex steroid estradiol and the synthetic androgen R1881 (methyltrienolone). Testosterone and dihydrotestosterone at 1 microgram/ml enhance the acid phosphatase synthesis by a factor of 3.5, while a hundred-fold lower concentration of the synthetic androgen R1881 induces an almost five-fold increase in the expression of this enzyme. The stimulation by all androgens tested and estradiol was dose-dependent. The synthetic glucocorticoid triamcinolone acetonide does not modulate the prostatic acid phosphatase expression in LNCaP cells, neither alone nor in combination with R1881.

Acid Phosphatase↗
PubMed1985

[Aminoglutethimide in the treatment of advanced prostatic cancer].

A total of ten previously castrated men with stage D carcinoma received 1000 mg aminoglutethimide and 50 mg/die cortisoneacetate. The patients were evaluated using the criteria of the National Prostate Cancer Project. No patients showed objective response, three patients had reduction of bone pain and subjective improvement. Pretreatment testosterone, prolactine and estradiol levels were measured. Three patients had a statistically significant elevation of testosterone levels.

Acid Phosphatase↗
PubMed1984

[Antegrade fine needle pyelography of transplanted kidneys].

In a poorly functioning renal transplant ureteral obstruction or perforation must be considered as a cause. Sonography and radionuclide scanning may demonstrate outflow obstruction and/or pararenal fluid collection, but do not usually provide sufficient information on the site of the lesion. In these cases we have successfully used fine needle puncture of the renal pelvis under continuous sonographic guidance and antegrade pyelography. Successful puncture was always possible and exact details of the renal pelvis and ureter were provided after contrast injection. No complications were seen after fine needle puncture. Sonographic guidance is ideal in respect to practicability and cost effectiveness if compared to computed tomography scanning. The technique has proven to be simple and safe to perform. It provides a quick and valuable diagnosis and superior anatomical details for reconstructive surgery.

Diagnosis, Differential↗
PubMed1984

Surgical correction of rectoprostatic fistula.

A rectoprostatic fistula is a rare complication of prostatic operations, and the literature on the subject is scanty. Three men were treated for rectoprostatic fistulas representing complications of prostatic surgery. Mason's transsphincteric transrectal operation resulted in prompt, primary healing of the fistula. Subsequent colostomy closure left all 3 patients with normal urinary and fecal control. A systematic three-step sequence of operation is advocated for the treatment of rectoprostatic fistulas. The Mason technique provides excellent exposure and reliable closure of rectourinary fistulas.

Aged↗
PubMed1984

Clinical assessment of solid phase immunoadsorbent assay of human prostatic acid phosphatase.

A new solid phase immunoenzyme assay for human prostatic acid phosphatase was tested in clinical practice. Clearly elevated levels of prostatic acid phosphatase (PAP) were found with advancing age and even more so in patients with benign prostatic hyperplasia (BPH). In patients with localized carcinoma of the prostate there was no elevation of levels above those observed in patients with BPH. When lymph node metastases were found at staging lymphadenectomy, the preoperative level of prostatic acid phosphatase was elevated in 7 of 12 cases. Good response to hormone treatment of metastatic carcinoma of the prostate was indicated by decrease of PAP-levels to normal. Rising levels often preceded the clinical manifestation of progression.

Acid Phosphatase↗
PubMed1984

[Prevention of complications following abdominal surgical urologic interventions by plasma protein substitutes].

A prospective randomised trial in 94 patients undergoing urological abdominal surgery has been carried out to evaluate the effect of postoperatively administered plasma proteins. A significant difference between the treatment group and the control group has been found in the incidence of bronchopulmonary complications. This may be due to the substitution of Alpha-1 antitrypsin as could be shown by determination of the activity of Alpha-1 antitrypsin levels. A positive trend but no significant differences could be demonstrated for wound healing and the need of antibiotics postoperatively.

Abdomen↗
PubMed1983

Circadian variation of different fractions of serum acid phosphatase.

The circadian variation of different fractions of serum acid phosphatase was determined in two men with a normal prostate, two men with benign prostatic hyperplasia, and four men with prostatic cancer. Serum samples were obtained every 2 hours from 8:00 a.m. until 6:00 a.m. the following day. An overall sample standard deviation of 1.98 U/liter was calculated for total acid phosphatase, 0.4 U/liter for tartrate-labile acid phosphatase, and 0.13 micrograms/liter for prostatic acid phosphatase as determined by immunoenzyme assay.

Acid Phosphatase↗
PubMed1983

[Surgical correction of prostato-rectal fistulas].

A recto-prostatic fistula is a rare complication of prostatic operations and the literature on the subject is scanty. Three men were treated for recto-prostatic fistulas representing complications of prostatic surgery. York Masons trans-sphincteric trans-rectal operation resulted in prompt, primary healing of the fistula. Subsequent colostomy closure left all three patients with normal urinary and fecal control. A systematic 3-step sequence of operation is advocated for the treatment of recto-prostatic fistulas. The York Mason operation provides excellent exposure and reliable closure of recto-urinary fistulas.

Aged↗
PubMed1983

[Significance of an immunoenzyme assay of the prostate-specific acid phosphatase (PAP) (E.C.3.1.3.2.) in prostatic carcinoma. Methods and initial clinical results].

The usefulness of a new specific immunoenzymatic assay for the prostatic acid phosphatase for diagnosis and monitoring of prostatic carcinoma has been investigated. The results include 200 healthy men without urologic anamnesis, 50 patients suffering from prostatic adenoma, and 152 patients with prostatic carcinoma. Out of 152 patients with prostatic carcinoma 110 were so-called therapy-responders and 42 were patients with progression of prostatic cancer. The immunoenzymatic assay for PAP shows good results for the separation of patients with progressive prostatic carcinoma, from those patients with a stationary prostatic cancer as well as for monitoring of prostatic carcinoma. The diagnostic value of the test has been found significantly higher than that of previous tests with different substrates. As this method allows the direct measurement of the activity of the specific prostatic acid phosphatase in U/l there is no need to run a standard-curve. It is recommended to use different "normal ranges" for patients with and without therapy. For monitoring mainly intraindividual studies are requested.

Acid Phosphatase↗