[Acute bilateral retinal necrosis in 2 stages. The role of herpes infection?].
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Biomedical subjects
Publications and source records attributed to H Saraux.
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Three cases of orbito-palpebral lymphangioma are reported. The three cases all have the common features: onset in early childhood, slow progression and extension of the tumor to other structures (palate and temporal fossa). The usual complications (hemorrhage and cellulitis) were documented in our cases. Biopsy of the lesions showed variably sized endothelial lined spaces without a capsule. Theses spaces contain eosinophilic material without blood elements. In two cases, chirurgical excision gave orbital edema. The authors think that orbital lymphangioma is a clinical entity. The treatment is difficult and small repeated excisions and cryotherapy are recommended.
A study of 9 cases of trigeminal noevus flammeus was performed. Eight had congenital glaucoma and where followed from 1 to 10 years. Only three had intracranial involvement. Hemangiomatosis was often atypical: including cavernous hemangioma, association with cutis marmorata telangiectatica congenital and bilateral involvement. Glaucoma was a mild congenital glaucoma in all cases improved by surgical treatment. Surgery was easily performed and a superficial capillary network on the sclera was seen in all patients. No genetic factor was demonstrated in our patients.
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Study of a case exhibiting an association of a right Stilling retraction syndrome with left auricle dysplasia, left 7th nerve paralysis and left lung dysplasia. This case supports an assertion by others that association of horizontal gaze paralysis and ear dysplasia is a clinical entity.
A case of unilateral central vein occlusion occurring in a normotensive patient with systemic lupus erythematosus (SLE) is reported. This vasculitis is related to SLE. In spite of the observation of circulating immune complex and a positive response to the human basophil degranulation test in the presence of bovine soluble retinal antigen, the real pathogenesis of this unilateral vasculitis remains obscure.
A case of snow erythropsia is described in a patient with pseudophakia (Binkhorst four loop len). Symptoms of the condition lasted a week and allowed us to define psychophysic and electrophysiological findings. Morphoscopic night threshold was raised (0,28 b/hm 2). Resistance to glare was very low. In the study of colour vision, answers for Beyne's lantern lights were: pink orange for white; grey for blue; purple for red; red for orange; white for green. Ishihara and Farnsworth tests showed a defect of the red-green type. With the Nagel anomaloscope the matching of colours was normal (Rayleigh match). Electrophysiological study showed a low value of the standing potential of the eye and a normal electroretinogram. It seems that the colour defect in erythropsia is a glare phenomenon due to high luminance.
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Ocular complications of sarcoidosis are encountered in about a third of cases. They are subacute or chronic conditions, the commonest being anterior, middle and posterior uveitis, and involvement of lacrimal apparatus. The measurement of the angiotensin converting enzyme has thrown new light on these troublesome problems.
The authors report three patients with systemic lupus erythematosus (S.L.E.) who developed primary retinal vasculitis. All patients showed evidence of four American Rheumatism Association diagnostic criteria for S.L.E. The first case consisted of a woman with retinal central vein occlusion. Auto-immunization against retinal S antigen was present. She improved under heparin therapy. In the second case, a young girl had chronic optic disk vasculitis for seven years. In the third case, retinal arterial occlusive disease was present with optic nerve involvement. The differential diagnosis with multiple sclerosis is discussed. S.L.E. is considered as autoimmune disease where circulating immune complexes play a major role in the pathogenesis. The ocular complications are probably a manifestation of the widespread systemic disease in patients without arterial hypertension. The authors summarize the ocular findings in S.L.E.: venous obstruction, constriction of retinal arteries, capillary vasculitis and disc neuritis. In some cases, there may be the first manifestations of the disease.
In three cases of intraocular silicone oil injection in which the histologic picture is observed at different time intervals, emphasis is given to the fact that fibrous tissue formation around silicone vesicles is a rather constant complication and of early occurrence. Thus, we believe that the removal of liquid silicone from the eye should not take place later than two or three months after the injection. In our first reported case, there was an association of silicone oil injection and vitrectomy with retinal detachment procedures and sympathetic ophthalmia. In the absence of evident histologic or clinical proof, we do not consider silicone oil injection itself as having induced the mechanisms of sympathetic ophthalmia.
The phenotype of a lymphoid orbital tumor is described, using monoclonal antibodies of the OKT series. The majority of tumor cells lacked surface immunoglobulins and bound OKT3, hence they arose from the T lineage. These cells belonged to the mature helper T cell subpopulation since a great proportion was recognized by OKT4 antibody. In contrast, a decrease in the peripheral blood OKT4+ pool was observed. The results demonstrate the importance of using a panel of markers, such as monoclonal antibodies, for the identification of cell derivation of lymphomas.
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