[Ex vivo renal surgery for extensive renal calculi; six cases report (author's transl)].
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Biomedical subjects
Publications and source records attributed to H Mitsuya.
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An estimation of the weight of the benign prostatic adenoma by quantitative analysis of the urethral pressure profile has been correlated with the surgically removed specimen in 23 patients. It has been found that the length of the continence zone cane be used as an index of prostatic weight. After operation the length of the continence zone fell into the normal range of the age matched controls.
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A 28-year-old man with immunodeficiency with hyper IgM was studied. His serum immunoglobulins were characterized by the absence of IgA and low level of IgG associated with high level of IgM. The in vitro pokeweed mitogen (PWM)-induced immunoglobulin synthesis by his peripheral blood lymphocytes was depressed completely for IgA and moderately for IgG although normal numbers and proportions of IgA- and IgG-bearing lymphocytes (on the surface) were demonstrated in the peripheral blood. His T cells could not help IgA production by either normal or his own B cells, whereas they were more efficient helpers for IgM production by his own B cells than were normal T cells. In addition, his B cells produced no IgA and less IgG than normal B cells when co-cultured with normal T cells. This suggests that the failure of IgA specific T helper activity and the maturation arrest of B cells at the stage of the switchover from IgM- to IgG- and/or IgA-producing cells may be the major cause for the hypogammaglobulinaemia in this patient. It is uncertain whether the maturation arrest of B cells is secondary to the T cell defect in helper function for IgA production.
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Several micturition parameters in healthy volunteers have been studied with digital computer analysis. The accuracy of the uroflowmeter has also been tested. Total voiding time, average flow rate, maximum flow rate, volume and time at maximum flow rate are all the function of volume voided. The first half of urinary volume is rapidly evacuated in the first one third of the total voiding time, and the rest in the remaining two thirds of the voiding period. When the constant stream hits at the center of the disk, the response of the flowmeter is fairly good. Once the urinary stream is accelerated and/or hits at the edge of the disk, the response is not reliable.
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