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H Lehmann

Publications and source records attributed to H Lehmann.

At least 181 records · Page 10Linked to original sources
PubMed1979

[Serological classification of post-transfusion hepatitis (author's transl)].

Post-transfusion hepatitis (PTH) remains to be a major hazard after massive blood transfusions. After 141 cardiac surgeries with massive blood transfusions the frequency of PTH reached 38%. The natural history of this type of hepatitis proved to be clinically mild but usually protracted. Icterus was found in one third. Serologically 46% of the PTH could be identified by HBs-Ag-testing as type B hepatitis. 39% revealed anti-HBs and 15% remained unclassified. HBs-Ag or anti-HBs were found in 40% patients without clinical or biochemical evidences of a hepatitis. The diagnosis of PTH still should rely on a synopsis of a typical clinical and biochemical hepatitis syndrome, characteristic serological findings and an adequate intervall between blood transfusion and outbreak of hepatitis.

Adult↗
PubMed1978

The myoglobin of an echidna (Tachyglossus aculeatus aculeatus).

The skeletal myoglobin of the echidna was composed of 153 residues. Its primary amino acid sequence has been determined and compared with that of platypus. Nine differences were found. The number of differences from known marsupial and eutherian myoglobin is about twice as much.

Amino Acid Sequence↗
PubMed1978

[The cest radiograph in Wegener's granuloma (author's transl)].

Wegener's granuloma belongs to the so-called collagenoses. It is characterized by focal vasculitis, necrotising granulomatous processes in the upper air passages and lung, as well as focal glomerulitis with swelling of the capsule and the formation of granulomatous glomerular lesions. In order of frequency the lungs, paranasal sinuses, pharynx, kidneys, joints, skin, eyes, ears, the heart and nerve tissue may be involved. Recently, Wolf and Fischbach (1976) reported six cases of Wegener's granuloma in this Journal, with radiological and pathological changes in the lungs. Typical changes which may be found radiographically are illustrated in the present paper based on four histologically confirmed cases of this relatively rare condition.

Aged↗
PubMed1978

Interaction between iron deficiency and alpha-thalassaemia: the in vitro effect of haemin on alpha-chain synthesis.

Two conditions are liable to lower the alpha:beta globin biosynthesis ratio in reticulocytes: iron deficiency and alpha-thalassaemia. The present paper studies the effect of haemin on reticulocytes from 12 patients who have alpha-thalassaemia and/or are iron deficient. The alpha:beta globin biosynthesis ratio was improved in all these cases. 4 showed initially an alpha:beta synthesis ratio usually associated with alpha-thalassaemia type-1; on the addition of haemin the ratio rose to that associated with alpha-thalassaemia type-2. In the other 8 patients the ratio was initially typical for alpha-thalassaemia type-2, and on addition of haemin the ratio became normal. It is suggested that in iron deficient patients a diagnosis of alpha-thalassaemia type-1 or type-2 cannot be made unless haemin has been added to the test system. If this is not done iron deficiency alone can cause the alpha:beta globin synthesis ratio to resemble that associated with alpha-thalassaemia type-2, and iron deficiency in combination with alpha-thalassaemia type-2 can cause the ratio to resemble that typical for alpha-thalassaemia type-1. Reticulocytes from 8 alpha-thalassaemic patients without iron deficiency did not show a marked haemin effect (less than 5%), and in 1 patient with iron overload, the ratio actually fell by about 10%.

Adolescent↗
PubMed1978

Beta-chain variants in Jamaican newborns.

In an electrophoretic study of 15,661 Jamaican cord bloods, 8 rare beta-chain variants were found in 18 subjects in addition to the common beta-chain variants, Hb S and Hb C. The heterozygote frequencies for Hb S and Hb C were 10.1% and 3.7% respectively. The most frequent of the rare beta-chain variants were Hb Korle Bu (beta 73 Asp leads to Asn) (7 cases) and Hb O su-Christiansborg (beta 52 Asp leads to Asn) (3 cases). One new beta-chain variant, Hb Caribbean (beta 91 Leu leads to Arg) was found.

Chromatography, Ion Exchange↗
PubMed1978

[Not Available].

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Germany↗