Biomedical subjects
Publications and source records attributed to H Lehmann.
A case report of a short ductus choledochus terminating in the bulbus duoden is presented. The patient suffered from recurrent gastric and duodenal ulcers. Peroral retrograde endoscopic choledochyography visualized this rare anomaly of the biliary system. Therapeutical and aetiological relationships between this anomaly and the ulcers are discussed.
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An acute life endangering bradycardy-tachycardy-syndrome in a 37 years old female could be referred to a rare familiar sinuatrial and atrioventricular arrhythmia with an inherited autosomal dominant trait. The patient's mother, three brothers, one sister and four children showed arrhythmias ranging from sinusbradycardia to second degree heart block. There was an obvious coincidence between intellectual retardation and the extent of the cardiac arrhythmia. Familial arrhythmias should be considered in instances of sudden death or rhythm disorders in young individuals.
Tryptic, peptic and chymotryptic peptides from the myoglobin of the Cape fox (Vulpes chama) have been aligned with the sequence of the myoglobin of the domestic dog. No amino acid difference was found. Seven carnivore myoglobins now known are compared amongst themselves and it is noted that though the differences between them are found in many different parts of the myoglobin molecule, there seems to be a higher incidence along the loop formed by helix G, the interhelical region GH and the helix H.
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The myoglobin of the fruit-bat (Rousettus aegyptiacus) has been investigated. It has 153 amino acid residues. When the possible therian ancestral myoglobin is taken into consideration, the myoglobin of the fruit-bat resembles most closely that of the hedgehog.
A new electronic transducer system has been developed for intraluminal pressure studies in the gastrointestinal tract. In contrast to other devices, inductance was used for the transformation of pressure into electrical signals. High sensitivity with a frequency response of 10(4) Hz guarantees accurate recording of sphincter as well as of peristaltic pressures. Pull-throughs can be carried out manually. Studies may be performed in the sitting as well as in the supine position since no hydraulic effects are present. No measurable temperature sensitivity was found; linearity is present in the physiological pressure range required. Small size, mechanical and electrical stability and simple handling make the PI-transducer system a suitable diagnostic tool for clinical as well as for investigatory purposes. By this method functional disorders of the esophagus, as in scleroderma, achalasia or hiatus hernia, of the pylorus and of the anal sphincter may be evaluated. The results of lower esophageal sphincter measurements in 30 asymptomatic volunteers and in 19 patients with symptomatic gastroesophageal reflux agree with the data obtained by conventional methods.
Whereas the myoglobin of the dolphin surprisingly resembles that of the sperm whale more than that of the porpoise, the myoglobin of a killer whale does not show this feature. It differs from the myoglobins of the dolphin in 6, of the porpoise in 8, and of the sperm whale in 14 positions. The residues in which the cetaceans differ are localised in one particular area of the molecule.
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Haemoglobin Ouled Rabath found only once before in an Algerian has been discovered at high frequency in the Kel Kummer Tuaregs in Mali. The tribe represents a 'genetic isolate'.
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