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Biomedical subjects

H Kaur

Publications and source records attributed to H Kaur.

At least 145 records · Page 8Linked to original sources
PubMed1982

An intravasal non-occlusive contraceptive device in rats.

An implantable miniature biogalvanic cell was developed to kill the spermatozoa in the vas deferens by an electric current. Experiments in vitro and in vivo showed that a combination of aluminum/silver electrodes connected with platinum wires with the vas deferens fluid as n electrolyte is effective in killing spermatozoa. Female rats paired with males having biogalvanic devices in the vas deferens, which remained patent, did not produce any young.

Aluminum↗
PubMed1982

Alloalbuminemia in North India.

Electrophoretic screening of sera from 550 individuals from Punjab, North India, revealed four cases of alloalbuminemia. Two albumin variants migrated slower and two migrated faster than the common albumin A. These variants were further analyzed by electrophoresis of their cyanogen bromide fragments to localize their molecular differences. One of the slow variants appears similar to, if not identical with, albumin B, with an altered cyanogen bromide fragment CNBr VII. The other slow variant appears to be a new variant (proposed name albumin Punjab) differing from albumin A in an altered fragment CNBr VI (which also occurs in albumins Kashmir and Adana) and in an altered fragment CNBr I. Among the fast variants, one has the same altered fragment CNBr V as albumin Naskapi, while the other appears to be a new variant (proposed name albumin Patiala) having an altered fragment CNBr VI. The presence of albumin Naskapi in Punjabis, North American Indians, and Eti Turks (previously reported) is consistent with the existence of a common ancestral population in which the mutation to Naskapi occurred before the migrations eastward and westward.

Blood Protein Electrophoresis↗
PubMed1981

Regulation of the activity of a calcium-activated neutral protease during differentiation of skeletal myoblasts.

A calcium-activated neutral protease activity appears concomitantly with myotube formation during the differentiation of a cell line of rat skeletal myoblasts. Other proteases such as cathepsin D and plasminogen activator, however, do not show any changes in their activities. The appearance of the protease is not fusion dependent, as judged by assays of fusion defective myoblast mutants. The formation of the protease is suppressed along with differentiation in the presence of 5-bromodeoxyuridine. Undifferentiated myoblasts contain a potent inhibitor of the protease. The inhibitor, which is probably proteinaceous in nature, is lost during the differentiation of the cells into myotubes. This mode of regulation of an enzyme during differentiation seems so far to be an unique example of its kind.

Animals↗
PubMed1981

Serum protein polymorphisms in goitre.

Serum albumin, ceruloplasmin, transferrin and haptoglobin were studied in 50 patients with both toxic and non-toxic forms of goitre. Albumin was monomorphic in all cases and its amount was substantially lower than normal in two patients. Ceruloplasmin was both qualitatively and quantitatively normal in all patients. No genetic variants of transferrin were encountered but 22% of the patients had this protein, at levels barely detectable by electrophoretic means. Such cases of hypotransferrinaemia occurred oftener in patients with the toxic form of goitre than in those with the non-toxic one. The distribution of haptoglobin types in patients was much the same as in the control blood donors. However, the patients had a greater incidence of ahaptoglobinaemia.

Blood Protein Electrophoresis↗
PubMed1981

Distribution of some genetic traits in three populations from Punjab, North India.

Three population groups, viz. Jat Sikh (192), Khatri (105) and Balmiki (108) were screened for haptoglobins, transferrins, Australia antigen, antigen Dd-reactivity and the ABO blood groups. The frequencies in Jat Sikhs, Khatris and Balmikis were 0.232, 0.186 and 0.140 respectively for Hp1 allele, 0.52%, 0.95% and 1.85% for Australia antigen, and 17.30%, 21.90% and 19.44% for antibodies against antigen Dd. The transferrins were all of type Tf C. The frequencies for the alleles A, B and O of the ABO system were 0.216, 0.239 and 0.545 in Jat Sikhs, 0.238, 0.320 and 0.442 in Khatris, and 0.196, 0.274 and 0.530 in Balmikis. Our tests showed these populations to be in Hardy-Weinberg equilibrium.

ABO Blood-Group System↗
PubMed1980

Some biochemical polymorphisms in members of the Gaddi tribe of Himachal Pradesh.

This study was carried out among members of the Gaddi tribe of Himachal Pradesh in north India. The genetic traits reported here include ABO blood groups, haptoglobin, transferrin, albumin, Gc, Australia antigen and antigen Dd. The frequencies of genes p, q and r for the ABO system were 0.212, 0.290 and 0.428. The Hp1 allele frequency (0.331) was markedly higher and that of Gc1 (0.700) somewhat lower than in most north Indian populations. The incidence of Australia antigen was 1.25%. There were no antigen Dd reactors.

ABO Blood-Group System↗
PubMed1977

Haptoglobin polymorphism in the Ladakhi population.

Haptoglobin polymorphism has been studied in 148 Ladakhis -- a Mongoloid population inhabiting the northern-most region of India. With a frequency of 0.270 for the allele Hp1 the Ladakhis compare favourably with other Mongoloid populations.

Electrophoresis, Starch Gel↗