Role of the baroreceptor-reflex in the mediation of responses following central angiotensin II administration.
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Biomedical subjects
Publications and source records attributed to H Becker.
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33 patients with primary and secondary brain tumours received radiotherapy. The therapeutic success was computer tomographically controlled. Only a temporary reduction in the size of the tumour could be observed during the radiotherapy. In connection with the reduction of the pathological findings in the CT, an improvement in the neurological findings was determined. A change in the tumour absorption may occur under the radiotherapy. An important indicator for tumour growth or regression is the change in the tumour absorption in computed tomography with the contrast medium. If the enhancement remains inspite of the radiotherapy, it can prognostically be considered as a detrimental factor. In the case of 10 of the 33 patients undergoing radiotherapy the tumour became isodense. No more enhancement was detectable. Isodensity may not be seen as a complete normalization of the brain tissue as could be established by histological investigations. On the other hand if again hypodense areas are revealed, it does not necessarily mean recurrence of tumour. Such an hypodense region then implies a radiogenic tumour-necrosis. Only the renewed enhancement after administering of the contrast medium in the area of the tumour must be considered as recurrence.
Vasopressin (AVP)-containing pathways from hypothalamic neurons have been shown to project to blood pressure controlling brain centres. This suggests that AVP neurons may be involved in central blood pressure regulation. The effects of central AVP receptor stimulation on blood pressure, heart rate and directly recorded efferent sympathetic nerve activity in the splanchnic nerve (SNA) were investigated in conscious chronically instrumented rats. Intracerebroventricular (i.c.v.) injections of AVP (1-100 ng) caused dose-dependent blood pressure increases (maximum 26.9 +/- 3.5 mmHg) together with marked rises in heart rate and SNA. More pre-treatment with the AVP receptor antagonist d(CH2)5AVP (3/micrograms i.c.v.) completely prevented the central responses to AVP. Intracarotid injection of the same AVP doses produced rises in blood pressure accompanied by drastic falls in heart rate and SNA, similar to those seen after i.v. AVP injection. Thus, stimulation of specific neuronal AVP receptors produces a characteristic haemodynamic and sympathetic response pattern with marked sympathetic nerve activation, which is clearly distinct from the responses to vascular AVP receptor stimulation. It is concluded that AVP pathways in the brain can contribute to central blood pressure control via regulation of sympathetic outflow to the periphery.
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The authors report on examinations performed via intravenous digital subtraction angiography in 19 patients with tumours of the pituitary gland who had been subjected to transnasal/transethmoidal removal of the tumour. It is easy to verify the course of the internal carotid artery in the region of the sinus cavernosus and thus the measurable distance of the internal carotid artery from the median line, as well as displacements of horizontal segments of the anterior cerebral artery. It is possible to exclude aneurysms. Basing on these results, bilateral conventional angiography of the carotid artery can usually be omitted. In this manner, diagnostic risk can be significantly reduced.
206 samples of commercially available infant food and their ingredients were examined for the content of B. cereus and coagulase-positive staphylococci as well as for the presence of salmonellae. B. cereus could be isolated from 64 samples with numbers between 3 and 460/g (only 2 samples greater than 100/g). Two samples contained coagulase-positive staphylococci (4/g each), and no sample salmonellae. Growth of B. cereus in reconstituted samples with counts of less than or equal to 100/g incubated at 20 and 25 degrees C, reached counts of 10(3)-10(4)/g after 6-9 h and 3-6 h, respectively. With regard to productivity and selectivity no differences between the media used (mannitol-egg yolk-phenolred-polymyxin-agar according to Mossel, Koopman and Jongerius, and polymyxin-pyruvate-egg yolk-mannitol-bromthymol blue-agar according to Holbrook and Anderson) could be observed.
Congenital bile duct dilatation is an autosomal recessive inherited disease. Pathologically tortuous dilated, dysplastic intrahepatic bile ducts were found. It may be associated with hepatic fibrosis (Grumbach's disease), or without (Caroli's disease). A common additional finding is an infantile polycystic kidney. Three cases are reported and the radiological and sonographic findings are discussed.
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Further applications of the rhomboid-to-W principle are discussed. The use of the flap in areas where other local flaps have not been successful is shown, together with an in-depth discussion of the planning and design of this flap.