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Biomedical subjects

G Zimmermann

Publications and source records attributed to G Zimmermann.

At least 91 records · Page 5Linked to original sources
PubMed1984

[Clinical aspects of pseudomyxoma peritonei].

On the basis of two cases the problems of peritoneal pseudomyxoma (PP) are discussed with respect to pathogenesis, clinical diagnosis and therapy. The abundant quantities of mucus present in the peritoneal cavity in this syndrome originate primarily in ruptured histologically malignant or benign mucous ovarian cystomas or benign mucocele or mucogenic carcinomas of the appendix, respectively. Independent of the histological findings the clinical course and consequently the prognosis of PP basically depends on the amounts of mucus present. Besides extirpation of the primary tumour therapy consists primarily in removing mucus as completely as possible, even in the form of repeated interventions. Additional measures are mainly confined to radiotherapy and cytostatic treatment. Recently new possibilities in preoperative diagnosis and postoperative control have been opened up by ultrasound and computed tomography.

Cystadenoma↗
PubMed1983

The effects of glyceryl trinitrate, isosorbide dinitrate and sodium nitroprusside on haemodynamics, coronary blood flow and myocardial oxygen consumption - an experimental study.

The influences of glyceryl trinitrate, isosorbide dinitrate and sodium nitroprusside intravenously on haemodynamics, coronary circulation and myocardial oxygen consumption were investigated in closed chest dogs (n = 8). In an attempt to simulate heart failure the dogs received blood transfusion (15 ml/kg) in the presence of halothane-induced myocardial depression. All three nitrates reduced the loads for the left ventricle. With isosorbide dinitrate and sodium nitroprusside the preload and pulmonary pressure decreased to a greater extent than with glyceryl trinitrate. The haemodynamic results suggest that sodium nitroprusside is the favourable nitrate in left ventricular failure because it produces a balanced reduction in the ratio of pre- and afterload. Four micrograms/kg X min sodium nitroprusside induced marked coronary dilatation; glyceryl trinitrate had only a slight coronary vasodilating effect. With isosorbide dinitrate the myocardial blood flow remained well adapted to oxygen demand, the coronary vascular resistance did not change. Sodium nitroprusside produced a significant change of the transmural myocardial blood distribution-expressed as the epi/endocardial blood flow ratio. The ratio was increased by sodium nitroprusside, much more than by glyceryl trinitrate or isosorbide dinitrate.

Animals↗
PubMed1983

The Indians have many terms for it: stuttering among the Bannock-Shoshoni.

This report follows by 23 years correspondence between Wendell Johnson and Sven Liljeblad in which Liljeblad pointed out that among North American "nonstuttering" Indians there were Indians who stuttered. He also reported several terms that referred to stuttering. An unpublished study reported by Frank confirmed Liljeblad's claims. Since we must rely on published reports, it is important to get these findings into print for future scholars. Though these findings in no way refute the claimed importance of linguistics and cultural variables as contributing to the development of stuttering, they do call to question evidence supporting the view that stuttering is a diagnosogenic disorder. Historical and sociological issues related to these contradictory findings are similar to those discussed by Freeman.

Culture↗
PubMed1982

Rapid determination of the luteinizing hormone for optimal timing of oocyte recovery.

Accurate prediction of ovulation is absolutely necessary to recover mature oocytes for in vitro fertilization. We have modified a commercially available LH-RIA Kit for blood and urine measurement and used the HI-Gonavis Kit for monitoring the present LH level. Post-menstruation (11th-16th day) laparoscopy or laparotomy was performed to inspect the follicle state and the oocyte quality, respectively. The precise time for harvesting oocytes after the beginning of LH increase is not known. Varying data of other research groups are discussed and some problems are described.

Adult↗
PubMed1982

[Current determination of ovulation time. 1. Rapid LH determination in serum and urine].

Short-term recording of LH rise is a possible approach to ovulation forecast. Hormone values in serum and four-hour urine can be obtained in three and half hours by modification of a commercial radio-immunological LH test. The results were compared with data obtained from the HI Gonavis test. Observable LH rise can be detected between three and six hours earlier by LH serum measurement, as compared to collected urine. Suitable information may be obtained also from LH urine assay, a non-invasive method of ovulation prediction.

Female↗
PubMed1982

[Current determination of ovulation time. 2. Optimization of timing for oocyte recovery].

Knowledge of probable ovulation date is essential to the recovery of pre-ovulatory oocytes for in vitro fertilisation. The authors used a commercially available LH-RIA kit for blood and urine samples together with the HI-Gonavis test for urine assay for high-accuracy determination of luteinising hormone (LH) in the peri-ovulatory cycle phase. Follicle status and oocyte quality were laparoscopically described of seven patients, between the eleventh and 16th days p.m. Optimum timing for oocyte recovery has not even become known by knowledge of LH rise. Different recommendations by other authors are discussed, and reference is made to unanswered problems.

Body Temperature↗
PubMed1981

[Is the intraoperative electrical stimulation test of Burge indispensable in order to ensure complete denervation in selective proximal vagotomy? (author's transl)].

The success of selective proximal vagotomy in the treatment of chronic duodenal ulcer is dependent on complete denervation of the proximal part of the stomach, as well as on the preservation of antral innervation. Inadequate nerve dissection results in therapeutic failure. The most frequent cause of recurrent ulcers is incomplete vagal denervation of the acid-secreting cells. Therefore, it would seem desirable to use an intraoperative test to check completeness of vagotomy, giving the surgeon the possibility of rectifying an inadequate nerve section still at the time of operation. Among several methods the electrical stimulation test described by Burge and Vane has gained general acceptance. However, the question of whether the intraoperative test actually improves the results of vagotomy remains equivocal. In an initial series of 39 vagotomies we ensured completeness of denervation by the electrical stimulation test. In a subsequent series of 44 operations vagotomy was performed without the test. The patients were re-examined one and again two years following operation (clinical evaluation, gastroscopy and/or X-ray examination). The results of this retrospective analysis using the classification of Visick showed no difference between the two series. Hence, we have no reason to suppose that omission of the intraoperative test will result in an increased number of incomplete vagotomies, provided the surgeon has gained his experience in this operative procedure by using the test to check his surgical technique, which thereby becomes standardized. Thereafter, the Burge test becomes dispensible.

Duodenal Ulcer↗
PubMed1981

Articulatory patterns of an adventitiously deaf speaker: implications for the role of auditory information in speech production.

Kinematic analysis of selected articulatory gestures of an adventitiously deaf speaker is reported. High speed cinefluorography and a semiautomated analysis system were used to describe the coordination of lip, jaw, tongue tip, and tongue dorsum. The coordination of voicing and movements also was analyzed. Compared to a speaker with normal hearing, the deaf speaker showed systematic timing differences in the VC (closing) portion of each utterance. Coordination of tongue dorsum with other structures showed obvious deviations. Voice termination was consistently later for the deaf speaker. Speculations about the role of auditory information in the long-term monitoring or calibration of speech gestures are offered.

Adult↗
PubMed1981

[Selective proximal vagotomy with intraoperative monitoring using Burge's test].

Only the test by Burge shows an effective evidence among the intraoperative control methods for testing the completeness of section during selective proximal vagotomy. The postoperative results are discussed in this study. 78 patients of 91 could be controlled endoscopically 3 to 60 months postoperatively. The result of the group with the Burge test (n = 38) does not differ essentially from the group without the Burge test (n = 40). However, the Burge test has a didactic importance certainly for surgeons in the training.

Electric Stimulation↗
PubMed1980

Articulatory behaviors associated with stuttering: a cinefluorographic analysis.

High speed (150 fps) cinefluorographic techniques were used to record articulatory movements during fluent and disfluent speech from four stutterers and control utterances from one normal speaker. Analyses of 11 perceptually disfluent utterances are reported. The results show: (1) interarticulator positions occurring in both perceptually fluent and disfluent utterances of stutterers were unlike those in fluent utterances of a normal speaker; (2) aberrant interarticulator positions preceded repetitive movements and static posturing; (3) consistent interarticulator repositioning which precedes termination of an oscillatory movement or static position often results in: (a) the lowering of the jaw or lip, and or (b) tongue shapes which resemble shapes found in normal speakers' fluent productions or the resting tongue shapes of the stutterer. The systematic repositioning and other patterns found are discussed in terms of possible neuromotor mechanisms involved in disfluency. It is suggested that reflex interactions among the muscles of articulation might account for some of these effects. A brief discussion of theoretical and therapeutic implications is included.

Adult↗