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Biomedical subjects

G Theodossiadis

Publications and source records attributed to G Theodossiadis.

At least 37 records · Page 2Linked to original sources

[Recurring vitreous body hemorrhages due to a retinal vessel drawn into the vitreous body cavity].

Six cases of recurrent vitreous hemorrhage are described. The hemorrhage was due to a retinal vessel rupture or injury caused by vitreous traction. The traction was exerted by the detached vitreous and the vessel drawn into its cavity without the simultaneous occurrence of a tear in the retinal area corresponding to the point of traction. The avulsed vessel was usually a small vein in the upper temporal fundus quadrant. The vessel either projected as a hooklet into the vitreous cavity or its peripheral end was found to be floating freely within the cavity after having moved away from the retina. Treatment consisted in laser coagulation alone or in conjunction with an indentation created by fixing a silicon episcleral explant. Recurrent vitreous hemorrhages caused by a retinal vessel drawn into the vitreous cavity after posterior vitreous detachment without a retinal tear have hitherto not been accorded the attention they deserve.

Adult↗

Determination of trace element Ag and Sc concentrations in human cataractous lenses.

For the detection and determination of the trace elements Ag and Sc in mature human cataractous lenses, the methods of neutron activation analysis was used. As regards Ag, attempts made in the past to establish its presence in the cataractous lens had failed, while Sc has not so far been thoroughly investigated. Our study of the two elements was also correlated to the age and sex of the patients with senile cataract. It was found that once senile cataract has fully matured, the determined trace-element concentrations no longer appear to be related to age and/or sex of the patients.

Aged↗

[Treatment of retinal detachment due to macular holes without application of any form of energy].

A new technique for treating retinal detachments due to macular holes avoids the application of any form of energy, cryo- or light-coagulation, or diathermy, to the macula. The only procedure employed involves the fixation of a silastic sponge, 14-17 mm long and 7.5 mm in diameter, to the posterior pole of the sclera in the vertical axis (12-6 o'clock), and suturing it at its extremities after stretching. This provokes an indentation obstructing the macular hole. Anatomical and functional results have been excellent, 17 of the 20 cases treated in this way obtaining useful vision due to avoidance of the perimacular zone.

Humans↗

[Argon laser coagulation in the treatment of active chorioretinitis (author's transl)].

Three cases of active chorioretinitis due to toxoplasmosis, which in the past had shown numerous recurrences, were subjected to argon laser coagulation after the preceding treatment with drugs had proved ineffective. Our procedure with the argon laser beam aimed not only at covering the entire area of the active chorioretinitis, but also at encircling and covering the old focus. In our case 2, in which in one phase of the condition argon laser coverage was confined merely to the active focus, there was a recurrence originating from another point of the same lesion. Argon laser coagulation appears to be effective, given the fact that no recurrence was observed after its application in any of our three cases over a follow-up period ranging from 2-4 years.

Adolescent↗

[Comparative study of virgin silk and polyglachine (Dexon) corneal sutures in rabbits (author's transl)].

An experimental study in rabbits compared corneal reaction to two types of sutures: 8.0 virgin-silk (Ethicon) and 7.0 Dexon (Davis-Geck). Results showed that the 8.0 virgin-silk (Ethicon) gives rise to a scar rapidly than the 7.0 Dexon (Davis-Geck). The degree of inflammation is smaller, the scar more solid and more regular than with 7.0 Dexon (Davis-Geck). In addition, the degree of neovascularisation of the cornea was more dense with the 8.0 virgin-silk (Ethicon) than the 7.0 Dexon (Davis-Geck) sutures.

Animals↗

How do tears drain? Technetium studies.

We examined the tear drainage system of twenty-fiv normal volunteers by scintillography with Technetium Tc 99m (Pertechnetate). We photographed the changes occurring in the lacrimal sac and nasolacrimal duct during closure and opening of the eyelids. Our findings support Jones' views of normal tear drainage. The tracer was concentrated in the lacrimal sac while the lids were closed for 3 minutes and descended into the nasolacrimal duct as soon as they opened.

Eyelids↗

[Clinical and pathologic-anatomical results following the application of a mobile argon-laser beam in aphakic pupillary block glaucoma (author's transl)].

In the last four years we have treated with the mobile argon-laser beam 25 cases of aphakic pupillary block glaucoma (p. b. g.). According to the time of manifestation of the p. b. g. the patients were divided into an "early" and a "late" group. In the "early" group (17 eyes) the glaucoma manifested itself 1--4 days after cataract extraction. In the "late" group (8 eyes) p. b. g. appeared from 4 weeks to 3 years after cataract extraction. In 14 of the 17 cases of the first group we achieved a prompt reformation of the anterior chamber and a considerable decrease of intraocular pressure immediately after laser application. In 3 cases of the first group, where the pupil was under relative or absolute mydriasis before argon-laser treatment, the mobile laser beam failed to produce satisfactory results. In all of the 8 patients of the "late" group a reformation of the anterior chamber was achieved, but in only 4 of them did i. o. pressure normalize owing to extensive anterior synechiae. Laser application left either very slight or no traces at all on the iris. In order to ascertain the actual effect of the laser beam upon the iris, we applied laser under identical conditions in eyes which had no glaucoma but were to undergo enucleation because of choroidal melanoma. The histological examination revealed a slight degree of hyperaemia of the iris as an oedema of the connective tissue, while the iris sphincter did not appear to be affected by laser treatment.

Aged↗

Management of aphakic pupillary block. A new argon-laser approach.

This communication concerns 9 cases of aphakic pupillary block with high intraocular pressure, which were managed successfully by means of a new argon-laser technique. This new approach consisted in the application at the collarette zone of the iris, 1.5 mm from the pupillary border, of a mobile argon-laser beam of variable intensity, ranging from 250 to 500 mW, of constant time (0.5 sec) and of fixed spot size (200 micron m). In some instances the beam was moved parallel and in other cases vertically to the pupillary border in the direction towards the ciliary portion of the iris. This technique ensures maximum retraction of the pupillary border, corresponding to the line of application, coupled with the least possible damage to the iris and a minimum of applications. Simultaneously with the retraction the posterior synechiae of the iris are detached and the outflow of the aqueous trapped in the posterior chamber released.

Cataract Extraction↗

[Changes of the corneal thickness after cataract extration (author's transl)].

A study of changes of the corneal thickness after cataract extraction was carried out on 149 patients. Cataract extraction was performed with partial knife incision or "ab externo" incision. The corneal thickness was measured with a Haag-Streit pachometer prior to cataract extraction and 4 days to 6 months after the operation. The investigation showed that the postoperative increase of the corneal thickness returns as before the operation.

Cataract Extraction↗

Retinal detachment treated by argon laser photocoagulation.

Argon laser photocoagulation was applied 2-3 weeks after implantation of episcleral silicone sponges as a second-step operation in 130 cases of retinal detachment. The chorioretinal scar for the occlusion of the tears was obtained exclusively with this procedure. Argon Laser used in cases with pronounced retinal elevation, i.e. where cryoapplication had proved inadequate or where a choroidal or retinal hemorrhage could be expected following cryoapplication. The advantages and disadvantages of the technique are evaluated with respect to the experience with cryoapplication.

Argon↗

[Treatment and follow-up of retinal tears associated with avulsed overlying retinal vessels (author's transl)].

The present clinical study is based on 17 cases of a specific clinical entity, which is characterised by a retinal break without retinal detachment, the tear being spanned by an avulsed patient retinal vessel invariably adjoining the operculum. The vessel was in the vitreous cavity and formed an arch above the break. All cases began with a sudden decrease or loss of visual acuity due to the rupture of the avulsed vessel and the occurrence of hemorrhages within the vitreous. These hemorrhages recurred in the course of the follow-up of the patients which lasted from 1-8 years. The recurrence of the bleeding was in most instances related to the mobility and the size of the vessel overlying the break. During treatment the cases were divided into two groups, group 1 comprising cases which were subjected only to light-coagulation, whereas in the cases of group 2 scleral buckling was performed in conjunction with cryopexy or light-coagulation. The comparatively best results were achieved in group 2. This condition is rare and amounted to only 1.5% of our total number of cases of retinal tears treated with light-coagulation during the last 8 years.

Aged↗